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LAST
LAST
Bulbul
@bulbul
Public
By
Bulbul
2646 days ago
Bioinformatics
Chromosome
Genome
NGS
Align
Compare
Similarity
http://last.cbrc.jp/
LAST can:
Handle
big
sequence data, e.g:
Compare two vertebrate genomes
Align billions of DNA reads to a genome
Indicate the
reliability
of each aligned column.
Use sequence quality data
properly
.
Compare DNA to proteins, with frameshifts.
Compare PSSMs to sequences
Calculate the likelihood of chance similarities between random sequences.
Do split and spliced alignment.
Train
alignment parameters for unusual kinds of sequence (e.g. nanopore).
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