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MetaPred2CS

https://github.com/martinjvickers/MetaPred2CS

MetaPred2CS Web server is a meta-predictor based on Support Vector Machine (SVM) that combines 6 individual sequence based protein-protein interaction prediction methods to predict prokaryotic two-component system protein-protein interactions (PPIs). The methods implemented in MetaPred2CS are 2 co-evolutionary methods: in-silico two hybrid (i2h) and mirror tree (MT) methods and 4 genomics context based methods: phylogenetic profiling (PP)gene fusion (GF)gene neighbourhood (GN) and and gene operon methods (GO).

 http://metapred2cs.ibers.aber.ac.uk/