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  • MetaSim A Sequencing Simulator for Genomics and Metagenomics.

MetaSim A Sequencing Simulator for Genomics and Metagenomics.

http://ab.inf.uni-tuebingen.de/software/metasim/

Our software can be used to generate collections of synthetic reads that reflect the diverse taxonomical composition of typical metagenome data sets. Based on a database of given genomes, the program allows the user to design a metagenome by specifying the number of genomes present at different levels of the NCBI taxonomy, and then to collect reads from the metagenome using a simulation of a number of different sequencing technologies. A population sampler optionally produces evolved sequences based on source genomes and a given evolutionary tree.