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  • AIRVF: a filtering toolbox for precise variant calling in Ion Torrent sequencing

AIRVF: a filtering toolbox for precise variant calling in Ion Torrent sequencing

https://sourceforge.net/projects/airvf/

AIRVF that works on flowgram, raw and mapped reads and called variants to reduce artifact-driven false variant calls. Tests on sequencing data of standard reference material showed up to ∼98% reduction of false variants when combined to conventional public pipelines and ∼48% to the in-house commercial solution, with a minimal loss of sensitivity

The program with a detailed manual is available at https://sourceforge.net/projects/airvf/