Results for "Breakpoint"
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The laboratory is focused on the discovery and analysis of structural variation (SVs) from genomic sequence data. As part of the 1000 Genomes Project and other endeavors, we have helped produce initial fine-scale maps using a variety of SV discovery approaches including: (i) paired-end mapping (o...Tags: Bioinformatics, Gene, Epigenomics, Structure Variation, Deletion, Breakpoint, Chromosome
2980 days ago
- Destruct is a tool for joint prediction of rearrangement breakpoints from single or multiple tumour samples. More at https://bitbucket.org/dranew/destruct
Tags: Bioinformatics, Computational Biology, destruct, Rearrangement, Breakpoint
2975 days ago
MGRA: Breakpoint graphs and ancestral genome reconstructions
MGRA (Multiple Genome Rearrangements and Ancestors) is a tool for reconstruction of ancestor genomes and evolutionary history of extant genomes. It takes as an input a set of genomes represented as sequences of genes (or synteny blocks) and produces such sequences for ancestral genomes at the in...Tags: MGRA, Breakpoint, graphs, ancestral, genome, reconstructions
2464 days ago
Reference-free prediction of rearrangement breakpoint reads
lideSort-BPR ( b reak p oint r eads) is based on a fast algorithm for all-against-all comparisons of short reads and theoretical analyses of the number of neighboring reads. When applied to a dataset with a sequencing depth of 100×, it finds ∼88% of the bre...Tags: Reference-free, prediction, rearrangement, breakpoint, reads
2238 days ago
- Breakpointer is a fast tool for locating sequence breakpoints from the alignment of single end reads (SE) produced by next generation sequencing (NGS). It adopts a heuristic method in searching for local mapping signatures created by insertion/deletions (indels) or more complex structural variant...
Tags: Breakpointer, local, mapping, artifacts, support, sequence, breakpoint, discovery, single-end, reads
2142 days ago
Chromosome breakpoint - a breakup to remember
Chromosome breakpoint refers to the physical location where a chromosome is broken and rearranged. Chromosome breakage can occur spontaneously or be induced by environmental factors such as radiation, chemicals, or viruses. The rearrangement of genetic material resulting from ...Tags: chromosome, breakpoint, evolution
413 days ago
