Tags: Bioinformatics, NGS, Comparative Genomics, Genome, LASTZ
2924 days ago
Ensembl comparative genomics resources
The Ensembl comparative genomics resources are one such reference set that facilitates comprehensive and reproducible analysis of chordate genome data. Ensembl computes pairwise and multiple whole-genome alignments from which large-scale synteny, per-base conservation scores and constrained ele...Tags: Bioinformatics, Computational Biology, Genome, RAD-Seq, NGS, Comparative Genomics, Resources, EnsEMBL
2974 days ago
Smash: An alignment-free method to find and visualise rearrangements between pairs of DNA sequences
Smash is a completely alignment-free method/tool to find and visualise genomic rearrangements. The detection is based on conditional exclusive compression, namely using a FCM (Markov model), of high context order (typically 20). For visualisation, Smash outputs a SVG image, with an ...Tags: Bioinformatics, Visualization, Alignment, Free, NGS, Comparative Genomics
2916 days ago
MEDEA: Comparative Genomic Visualization with Adobe Flash
As the number of sequence and annotated genomes grows larger, the need to understand, compare, and contrast the data becomes increasingly important. Using the power of the human visual system to detect trends and spot outliers is necessary in such large and complex data sets. More at http:/...Tags: Bioinformatics, NGS, Visualization, Chromosome, Comparative genomics
2916 days ago
SATSUMA : Highly sensitive whole-genome synteny alignments.
Satsuma is a whole-genome synteny alignment program. It takes two genomes, computes alignments, and then keeps only the parts that are orthologous, i.e. following the conserved order and orientation of features, such as protein coding genes, non-coding genes, or neutral sequences. Satsuma does no...Tags: Bioinformatics, NGS, Sequence, Alignment, Synteny, Comparative genomics, Genomics
2899 days ago
Tags: Bioinformatics, Musrsaki, Plot, Synteny, Genome, Viewer, Comparative genomics
2759 days ago
Comparative genomics educational material and papers bookmarks
Alignment of the porcine genome against seven other mammalian genomes (Supplementary Information) identified homologous synteny blocks (HSBs). Using porcine HSBs and stringent filtering criteria, 192 pig-specific evolutionary breakpoint regions (EBRs) were located. The number of porcine EBRs is c...Tags: Bioinformatics, Comparative genomics, Genomics, Chromosome, Synteny, Evolution
2719 days ago
Method in Comparative genomics !!
We present methods for the automatic determination of genome correspondence. The algorithms enabled the automatic identification of orthologs for more than 90% of genes and intergenic regions across the four species despite the large number of duplicated genes in the yeast genome. The remaining a...Tags: Bioinformatics, Comparative genomics, Genomics, Chromosome, Analysis, Method, Evolution
2719 days ago
Tags: Bioinformatics, Comparative genomics, Genomics, Structure Variation, SV, NGS
2688 days ago
GenomeRing: alignment visualization based on SuperGenome coordinates
The number of completely sequenced genomes is continuously rising, allowing for comparative analyses of genomic variation. Such analyses are often based on whole-genome alignments to elucidate structural differences arising from insertions, deletions or from rearrangement events. Computational to...Tags: Bioinformatics, Plot, Synteny, Genome, Viewer, Comparative genomics
2649 days ago