Results for "DNA"


  • Molecular Genetics Lecture

    "Robert Sapolsky makes interdisciplinary connections between behavioral biology and molecular genetic influences. He relates protein synthesis and point mutations to microevolutionary change, and discusses conflicting theories of gradualism and punctuated equilibrium and the influence of epigenet...

    Tags: molecular genetics, DNA, protein, mutation, genomics, genetics, epigenetics, molecular evolution

    1611 days ago

  • methylKit

    methylKit is an R package for DNA methylation analysis and annotation from high-throughput bisulfite sequencing. The package is designed to deal with sequencing data from RRBS and its variants, but also target-capture methods such as Agilent SureSelect methyl-seq. In addition, methylKit can deal ...

    Tags: Bioinformatics, methylKit, Methylation, DNA, Analysis, Genome, NGS, Sequence

    631 days ago


    The automated reconstruction of genome sequences in ancient genome analysis is a multifaceted process. EAGER encompasses both state-of-the-art tools for each step as well as new complementary tools tailored for ancient DNA data within a single integrated solution in an easily accessible format. ...

    Tags: Bioinformatics, Ancient, EAGER, Genome, DNA, Sequence, NGS

    441 days ago

  • FSA: Fast Statistical Alignment

    FSA is a probabilistic multiple sequence alignment algorithm which uses a "distance-based" approach to aligning homologous protein, RNA or DNA sequences. Much as distance-based phylogenetic reconstruction methods like Neighbor-Joining build a phylogeny using only pairwise divergence estimates, FS...

    Tags: Bioinformatics, FSA, Fast, Statistical, Alignment, DNA, Sequence

    383 days ago

  • DnaSP v5: a software for comprehensive analysis of DNA polymorphism data

    DnaSP is a software package for a comprehensive analysis of DNA polymorphism data. Version 5 implements a number of new features and analytical methods allowing extensive DNA polymorphism analyses on large datasets. Among other features, the newly implemented methods allow for: (i) analyses on mu...

    Tags: Bioinformatics, DnaSP, Software, Analysis, DNA, Polymorphism

    383 days ago


    DIAMOND is a sequence aligner for protein and translated DNA searches and functions as a drop-in replacement for the NCBI BLAST software tools. It is suitable for protein-protein search as well as DNA-protein search on short reads and longer sequences including contigs and assemblies, providing a...

    Tags: Bioinformatics, Alignment, DIAMOND, BLAST, DNA, Protein

    303 days ago

  • Tetra-Nucleotide Analysis

    A tetra-nucleotide is a fragment of DNA sequence with 4 bases (e.g. AGTC or TTGG). Pride et al. (2003) showed that the frequency of tetra-nucleotides in bacterial genomes contain useful, albeit weak, phylogenetic signals. Even though tetra-nucleotide analysis (TNA) utilizes the informat...

    Tags: Bioinformatics, Tetra-Nucleotide, Analysis, Frequency, DNA, Phylogeny, Algorithms

    296 days ago


    Chromosomal rearrangement events are caused by abnormal breaking and rejoining of DNA molecules. They are responsible for many of the cancer related diseases. Detecting the DNA breaking and repairing mechanism, therefore, may offer vital clues about the pathologic causes and diagnostic/therapeuti...

    Tags: Chromosomal, rearrangement, events, abnormal, breaking, DNA, SLIDESORT-BPR

    96 days ago

  • ACANA: An accurate and consistent alignment tool for DNA sequences

    ACANA is an accurate and consistent alignment tool for DNA sequences. ACANA is specifically designed for aligning sequences that share only some moderately conserved regions and/or have a high frequency of long insertions or deletions. It attempts to combine the best of local and global alignment...

    Tags: ACANA, accurate, alignment, tool, DNA, sequences

    80 days ago

  • SMASH: An alignment-free tool to find and visualise rearrangements between pairs of DNA sequences

    SMASH is a completely alignment-free method to find and visualise rearrangements between pairs of DNA sequences. The detection is based on relative compression, namely using a FCM, also known as Markov model, of high context order (typically 20). The method has been approached with a tool (a...

    Tags: SMASH, alignment-free, tool, find, visualise, rearrangements, pairs, DNA, sequences

    65 days ago