Results for "DNA"
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"Robert Sapolsky makes interdisciplinary connections between behavioral biology and molecular genetic influences. He relates protein synthesis and point mutations to microevolutionary change, and discusses conflicting theories of gradualism and punctuated equilibrium and the influence of epigenet...Tags: molecular genetics, DNA, protein, mutation, genomics, genetics, epigenetics, molecular evolution
3863 days ago
Nucl2Vec: Local alignment of DNA sequences using Distributed Vector Representation
We demonstrate a novel approach forlocal alignment of DNA reads with respect to reference genome.For this process we have used Skip-gram model for creatingencoding(Nucl2Vec) and k-nearest neighbor for the alignment.With our new approach we have reduced computation cost forlocal alignment , while ...Tags: Nucl2Vec, Local, alignment, DNA, sequences, Distributed, Vector, Representation
1136 days ago
- methylKit is an R package for DNA methylation analysis and annotation from high-throughput bisulfite sequencing. The package is designed to deal with sequencing data from RRBS and its variants, but also target-capture methods such as Agilent SureSelect methyl-seq. In addition, methylKit can deal ...
Tags: Bioinformatics, methylKit, Methylation, DNA, Analysis, Genome, NGS, Sequence
2883 days ago
- The automated reconstruction of genome sequences in ancient genome analysis is a multifaceted process. EAGER encompasses both state-of-the-art tools for each step as well as new complementary tools tailored for ancient DNA data within a single integrated solution in an easily accessible format. ...
Tags: Bioinformatics, Ancient, EAGER, Genome, DNA, Sequence, NGS
2692 days ago
FSA: Fast Statistical Alignment
FSA is a probabilistic multiple sequence alignment algorithm which uses a "distance-based" approach to aligning homologous protein, RNA or DNA sequences. Much as distance-based phylogenetic reconstruction methods like Neighbor-Joining build a phylogeny using only pairwise divergence estimates, FS...Tags: Bioinformatics, FSA, Fast, Statistical, Alignment, DNA, Sequence
2635 days ago
DnaSP v5: a software for comprehensive analysis of DNA polymorphism data
DnaSP is a software package for a comprehensive analysis of DNA polymorphism data. Version 5 implements a number of new features and analytical methods allowing extensive DNA polymorphism analyses on large datasets. Among other features, the newly implemented methods allow for: (i) analyses on mu...Tags: Bioinformatics, DnaSP, Software, Analysis, DNA, Polymorphism
2635 days ago
- DIAMOND is a sequence aligner for protein and translated DNA searches and functions as a drop-in replacement for the NCBI BLAST software tools. It is suitable for protein-protein search as well as DNA-protein search on short reads and longer sequences including contigs and assemblies, providing a...
Tags: Bioinformatics, Alignment, DIAMOND, BLAST, DNA, Protein
2555 days ago
- A tetra-nucleotide is a fragment of DNA sequence with 4 bases (e.g. AGTC or TTGG). Pride et al. (2003) showed that the frequency of tetra-nucleotides in bacterial genomes contain useful, albeit weak, phylogenetic signals. Even though tetra-nucleotide analysis (TNA) utilizes the informat...
Tags: Bioinformatics, Tetra-Nucleotide, Analysis, Frequency, DNA, Phylogeny, Algorithms
2548 days ago
- Chromosomal rearrangement events are caused by abnormal breaking and rejoining of DNA molecules. They are responsible for many of the cancer related diseases. Detecting the DNA breaking and repairing mechanism, therefore, may offer vital clues about the pathologic causes and diagnostic/therapeuti...
Tags: Chromosomal, rearrangement, events, abnormal, breaking, DNA, SLIDESORT-BPR
2348 days ago
ACANA: An accurate and consistent alignment tool for DNA sequences
ACANA is an accurate and consistent alignment tool for DNA sequences. ACANA is specifically designed for aligning sequences that share only some moderately conserved regions and/or have a high frequency of long insertions or deletions. It attempts to combine the best of local and global alignment...Tags: ACANA, accurate, alignment, tool, DNA, sequences
2332 days ago
