The Story of You: ENCODE and the human genome
Ever since a monk called Mendel started breeding pea plants we've been learning about our genomes. In 1953, Watson, Crick and Franklin described the structure of the molecule that makes up our genomes: the DNA double helix. Then, in 2001, scientists wrote down the entire 3-billion letter code con...Tags: ENCODE, Genome, Non-coding DNA, DNA, Animation
3896 days ago
Tags: bioinformatics, genomics, metagenomics, phylogeny, gene expression, cancer, marine genomics, ENCODE, conference
3886 days ago
MIT Computational Biology Group
My research group consists primarily of computer science graduate students and postdocs with expertise in algorithms, statistical inferences and machine learning, and sharing a passion for understanding fundamental biological problems. We work in a highly interdisciplinary environment at the i...Tags: Bioinformatics, Computational Biology, Genomics, RNAseq, NGS, Chromatin, RNA, Manolis Kellis, Chromosome, ENCODE
3415 days ago
MAGIC: A tool for predicting transcription factors and cofactors driving gene sets using ENCODE data
The algorithm presented herein, Mining Algorithm for GenetIc Controllers (MAGIC), uses ENCODE ChIP-seq data to look for statistical enrichment of TFs and cofactors in gene bodies and flanking regions in gene lists without an a priori binary classification of genes as...Tags: MAGIC, tool, predicting, transcription, factors, cofactors, driving, gene, sets, ENCODE, data
1245 days ago
Tags: ENCODE, Project, Genome, Reference, Data, Ftp, Download, Human
952 days ago
Encode sequencing data freely available to download and use for academic means
In Encode, regulatory elements investigated via DNA hypersensitivity assays, assays of DNA methylation, and chromatin immunoprecipitation (ChIP) of proteins that interact with DNA, including modified histones and transcription factors, followed by sequencing (ChIP-Seq). More information: h...Tags: Encode, UCSC, genome browser, Sequencing, RNA-Seq, Chip-Seq, Epigenomics, Methylation, histone modification, regulatory elements, HMM
3695 days ago
Prof. Dr. rer. nat. Jeanette Erdmann's Lab
Her prestigious lab working on Integrative and Experimental genomics to understand the underlying mechanism thats able to define an inherited predisposition of coronary artery disease (CAD) and myocardial infarction (MI) via GWAS, different Sequencing technologies and Functional genomics. Her la...Tags: Cardiovascular disease, GWAS, Exome Sequencing, non-coding SNPs, Encode, Epigenome
2320 days ago