CNIDARIA: fast, reference-free phylogenomic clustering
Motivation: Identification of biological specimens is a major requirement for a range of applications. Reference-free methods analyse unprocessed sequencing data without relying on prior knowledge, but these do not scale to arbitrarily large genomes and arbitrarily large phylogenetic distances. ...Tags: Bioinformatics, CNIDARIA, Fast, Reference-free, Phylogenomic, Clustering, NGS
2863 days ago
FSA: Fast Statistical Alignment
FSA is a probabilistic multiple sequence alignment algorithm which uses a "distance-based" approach to aligning homologous protein, RNA or DNA sequences. Much as distance-based phylogenetic reconstruction methods like Neighbor-Joining build a phylogeny using only pairwise divergence estimates, FS...Tags: Bioinformatics, FSA, Fast, Statistical, Alignment, DNA, Sequence
2629 days ago
FOGSAA: Fast Optimal Global Sequence Alignment Algorithm
Sequence alignment algorithms are widely used to infer similarirty and the point of differences between pair of sequences. FOGSAA is a fast Global alignment algorithm. It is basically a branch and bound approach which starts branch expansion in a greedy way taking the symbols from the given pair ...Tags: FOGSAA, Fast, Optimal, Global, Sequence, Alignment, Algorithm
2323 days ago
lordFAST: sensitive and Fast Alignment Search Tool for LOng noisy Read sequencing Data
lordFAST is a sensitive tool for mapping long reads with high error rates. lordFAST is specially designed for aligning reads from PacBio sequencing technology but provides the user the ability to change alignment parameters depending on the reads and application. lordFAST, a novel long-read mapp...Tags: lordFAST, sensitive, Fast, Alignment, Search, Tool, LOng, noisy, Read, sequencing, Data
1970 days ago
Flye: Fast and accurate de novo assembler for single molecule sequencing reads
Flye is a de novo assembler for single molecule sequencing reads, such as those produced by PacBio and Oxford Nanopore Technologies. It is designed for a wide range of datasets, from small bacterial projects to large mammalian-scale assemblies. The package represents a complete pipeline: it takes...Tags: Flye, Fast, accurate, de novo, assembler, single, molecule, sequencing, reads, ngs, assembly
1843 days ago
RaGOO: Fast Reference-Guided Scaffolding of Genome Assembly Contigs
Alonge M, Soyk S, Ramakrishnan S, Wang X, Goodwin S, Sedlazeck FJ, Lippman ZB, Schatz MC: Fast and accurate reference-guided scaffolding of draft genomes. bioRxiv 2019. RaGOO is a tool for coalescing genome assembly contigs into pseudochromosomes via minimap2 alignments to a close...Tags: RaGOO, Fast, Reference-Guided, Scaffolding, Genome, Assembly, Contigs
1828 days ago
Flye: Fast and accurate de novo assembler for single molecule sequencing reads
Flye is a de novo assembler for single molecule sequencing reads, such as those produced by PacBio and Oxford Nanopore Technologies. It is designed for a wide range of datasets, from small bacterial projects to large mammalian-scale assemblies. The package represents a complete pipeline: it takes...Tags: Fast, accurate, de novo, assembler, single, molecule, sequencing, reads
1749 days ago
RaGOO: Fast Reference-Guided Scaffolding of Genome Assembly Contigs
Alonge M, Soyk S, Ramakrishnan S, Wang X, Goodwin S, Sedlazeck FJ, Lippman ZB, Schatz MC: Fast and accurate reference-guided scaffolding of draft genomes. bioRxiv 2019. RaGOO is a tool for coalescing genome assembly contigs into pseudochromosomes via minimap2 alignments to a close...Tags: RaGOO, Fast, Reference, Guided, Scaffolding, Genome, Assembly, Contigs, NGS
1636 days ago
CLARK: Fast, accurate and versatile sequence classification system
CLARK, a method based on a supervised sequence classification using discriminative k-mers. Considering two distinct specific classification problems (see the article for details), namely (1) the taxonomic classification of metagenomic reads to known bacterial genomes, and (2) the assignment ...Tags: CLARK, Fast, accurate, versatile, sequence, classification, system, bacteria
1525 days ago
DADA2: Fast and accurate sample inference from amplicon data with single-nucleotide resolution
The DADA2 tutorial goes through a typical workflow for paired end Illumina Miseq data: raw amplicon sequencing data is processed into the table of exact amplicon sequence variants (ASVs) present in each sample. The DADA2 Workflow on Big Data goes through workflow op...Tags: DADA2, Fast, accurate, sample, inference, amplicon, data, single-nucleotide, resolution
1255 days ago