Results for "Genome"

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  • Bandage: interactive visualization of de novo genome assemblies

    Bandage (a Bioinformatics Application for Navigating De novo Assembly Graphs Easily) is a tool for visualizing assembly graphs with connections. Users can zoom in to specific areas of the graph and interact with it by moving nodes, adding labels, changing colors and extracting sequ...

    Tags: Bandage, interactive, visualization, de novo, genome, assemblies

    13 days ago

  • COPE: an accurate k-mer-based pair-end reads connection tool to facilitate genome assembly

    An efficient tool called Connecting Overlapped Pair-End (COPE) reads, to connect overlapping pair-end reads using k-mer frequencies. We evaluated our tool on 30× simulated pair-end reads from Arabidopsis thaliana with 1% base error. COPE connected over 99% of reads with 98.8% accuracy, whic...

    Tags: COPE, accurate, k-mer, pair-end, reads, connection, tool, genome, assembly

    12 days ago

  • Why are de Bruijn #graphs useful for #genome #assembly? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531759/

    Tags: graphs, genome, assembly

    10 days ago

  • jobTree based python wrapper to run the genome simulation tool suite Evolver

    evolverSimControl (eSC) can be used to simulate multi-chromosome genome evolution on an arbitrary phylogeny (Newick format). In addition to simply running evolver, eSC also automatically creates statistical summaries of the simulation as it runs including text and image files. Also...

    Tags: jobTree, python, wrapper, genome, simulation, tool, suite, Evolver

    9 days ago

  • kSNP3.0: SNP detection and phylogenetic analysis of genomes without genome alignment or reference genome

    Sept. 20, 2017 Version 3.1 released. Major upgrade. Version 3.1 fixes the problems with SNP annotation that arose when NCBI discontinued use of GI numbers. Please read carefully the Preface (page 3) and the File of annotated genomes section (pages 9-10) in the version 3.1 User Guide. Thanks to To...

    Tags: kSNP3.0, SNP, detection, phylogenetic, analysis, genomes, alignment, reference, genome

    9 days ago

  • Mugsy: multiple whole genome alignment tool

    Mugsy is a multiple whole genome aligner. Mugsy uses Nucmer for pairwise alignment, a custom graph based segmentation procedure for identifying collinear regions, and the segment-based progressive multiple alignment strategy from Seqan::TCoffee. Mugsy accepts draft genomes in the form of multi-FA...

    Tags: Mugsy, multiple, whole, genome, alignment, tool

    9 days ago

  • Tools for bacterial whole genome annotation

    RAST – Web tool (upload contigs), uses the subsystems in the SEED database and provides detailed annotation and pathway analysis. Takes several hours per genome but I think this is the best way to get a high quality annotation (if you have only a few genomes to annotate). Pr...

    Tags: Tools, bacterial, whole, genome, annotation, prokaryotic, genes

    24 hours ago

  • Mash: fast genome and metagenome distance estimation using MinHash

    Mash is normally distributed as a dependency-free binary for Linux or OSX (see https://github.com/marbl/Mash/releases). This source distribution is intended for other operating systems or for development. Mash requires c++11 to build, which is available in and GCC >= 4.8 and OSX >= 10....

    Tags: Mash, fast, genome, metagenome, distance, estimation, MinHash

    5 days ago

  • Regular Expression Cheat Sheet

    The Regular Expression are the sole of Perl language, and for bioinformatician it is just a magical stick to resolve gingatic string data. We did not find any good and user friendly regular expression cheat sheet, hence write our own cheat sheet. The Regular Expressions Cheat Sheet, a quick ...

    Tags: Cheat Sheets, Perl, Regular Expressions, Genome, Strings

    1622 days ago

  • Is reference genome necessary for gene expression study in transcriptome sequencing or for variant discovery in genome sequencing?

    Like in case of plant genomes where nature of genome is too complex and huge in size to accomplish complete de novo assembly by current sequencing technology. What would be alternate solution? Can we live in reference free world?

    Tags: Sequencing, RNA, DNA, Genome

    1614 days ago