Tags: molecular genetics, DNA, protein, mutation, genomics, genetics, epigenetics, molecular evolution
3858 days ago
STRUM: structure-based prediction of protein stability changes upon single-point mutation
STRUM is a method for predicting the fold stability change (ΔΔG) of protein molecules upon single-point nsSNP mutations. STRUM adopts a gradient boosting regression approch to train the Gibbs free-energy changes on a variety of features at different levels of sequence and structure pr...Tags: STRUM, structure-based, prediction, protein, stability, changes, single-point, mutation
2048 days ago
Tags: maftools, maf, format, snp, variant, genome, mutation
855 days ago
Tags: Bioinformatics, DIAL, Mutation, Genome, Reference, Pipeline
2606 days ago