...pen-source and available for free download.
PIRS: PIRS (short for Profile-based Illumina pair-end Reads Simulator) is a short read simulator that uses a profile-based approach to generate sy...
...stical-programming-languages-to-study-for-a-bioinformatician
You can also found several other material at http://bioinformaticsonline.com/groups/profile/93/r-and-bioconductor