Tags: Magic-BLAST, mapping, next-generation, RNA, DNA, sequencing, whole, genome, transcriptome.
2304 days ago
bpRNA: large-scale automated annotation and analysis of RNA secondary structure
bpRNA, a novel annotation tool capable of parsing RNA structures, including complex pseudoknot-containing RNAs, to yield an objective, precise, compact, unambiguous, easily-interpretable description of all loops, stems, and pseudoknots, along with the positions, sequence, and flanking base pairs ...Tags: bpRNA, large-scale, automated, annotation, analysis, RNA, secondary, structure
2157 days ago
P_RNA_scaffolder: a fast and accurate genome scaffolder using paired-end RNA-sequencing reads
P_RNA_scaffolder is a novel scaffolding tool using Pair-end RNA-seq to scaffold genome fragments. The method is suitable for most genomes. The program could utilize Illumina Paired-end RNA-sequencing reads from target speciesies. Our method provides another practical alternative to existing mate-...Tags: P_RNA_scaffolder, fast, accurate, genome, scaffolder, paired-end, RNA, sequencing, reads, scaffold
2050 days ago
iRNAD: a computational tool for identifying D modification sites in RNA sequence
iRNAD, for identifying D modification sites in RNA sequence. In this predictor, the RNA samples derived from five species were encoded by nucleotide chemical property and nucleotide density. Support vector machine was utilized to perform the classification. http://lin-group.cn/server/iRNAD...Tags: iRNAD, computational, tool, identifying, modification, sites, RNA, sequence
1799 days ago
The El-Sherif Group, Chair of Developmental Biology, Department of Biology - PhD Position
El-Sherif lab studies how genes are regulated to mediate patterning in Development. We use live and super-resolution imaging in addition to computational modeling to understand transcription dynamics at the single-cell level in three model systems: the fruit fly Drosophila melanogaster, the beetl...Tags: imaging, modeling, microfluidics, single-cell, DNA, RNA, microscopy
1551 days ago
iSeqQC: a tool for expression-based quality control in RNA sequencing
iSeqQC, an expression-based QC tool that detects outliers either produced due to variable laboratory conditions or due to dissimilarity within a phenotypic group. iSeqQC implements various statistical approaches including unsupervised clustering, agglomerative hierarchical clustering and correlat...Tags: iSeqQC, tool, expression-based, quality, control, RNA, sequencing
1523 days ago
Curated set of ribosomal RNA (rRNA) reference sequences (targeted loci) with verifiable organism
MCBI have a curated set of ribosomal RNA (rRNA) reference sequences (targeted loci) with verifiable organism sources and current names. This set is critical for correctly identifying and classifying prokaryotic (bacteria and archaea) and fungal samples. To provide easy access to these sequences, ...Tags: Curated, ribosomal, RNA, rRNA, reference, sequences, targeted, loci, verifiable, organism, 16S, 18S, 28S, ribosomal, RNA
1516 days ago
HNADOCK: a nucleic acid docking server for modeling RNA/DNA–RNA/DNA 3D complex structures
The HNADOCK server is to predict the binding complex structure between two nucleic acid molecules through a hierarchical docking algorihtm of an FFT-based global search strategy and an intrinsic scoring function for nucleic acid interactions. Users are required to provide the three-dimensional (3...Tags: HNADOCK, nucleic, acid, docking, server, modeling, RNA, DNA–RNA, DNA, 3D, complex, structures
1413 days ago