Tags: Bioinformatics, Computational Biology, Genome, Stability, Replication, Chromosome, Cancer, Oxford
3461 days ago
STRUM: structure-based prediction of protein stability changes upon single-point mutation
STRUM is a method for predicting the fold stability change (ΔΔG) of protein molecules upon single-point nsSNP mutations. STRUM adopts a gradient boosting regression approch to train the Gibbs free-energy changes on a variety of features at different levels of sequence and structure pr...Tags: STRUM, structure-based, prediction, protein, stability, changes, single-point, mutation
2016 days ago