Results for "cancer"
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Chromosomal rearrangement events are caused by abnormal breaking and rejoining of DNA molecules. They are responsible for many of the cancer related diseases. Detecting the DNA breaki...2341 days ago
Computational Genomics: Applied Comparative Genomics
...genome assembly & comparative genomics, variant identification & analysis, gene expression & regulation, personal genome analysis, and cancer genomics. The grading will be...2332 days ago
Reference-free prediction of rearrangement breakpoint reads
...quencing depth of 100×, it finds ∼88% of the breakpoints correctly with no false-positive reads. Moreover, evaluation on a real prostate cancer dataset shows that the propos...2233 days ago
- Manta calls structural variants (SVs) and indels from mapped paired-end sequencing reads. It is optimized for analysis of germline variation in small sets of individual...
2152 days ago
Platypus: A Haplotype-Based Variant Caller For Next Generation Sequence Data
...datasets as part of the Thousand Genomes and WGS500 projects, and is being used in clinical sequencing trials in the Mainstreaming Cancer Genetics programme. ...2002 days ago
- The consequences of alterations in the DNA of cancer cells and subsequent vulnerabi...s project aims to assign a dependency to every cancer cell in a patient which could.... This knowledge is foundational for precision cancer medicine.
1526 days ago
SVEngine: Allele Specific and Haplotype Aware Structural Variants Simulator
...s (see Manual) or specific variant information as specified in VAR files (see Manual) and NEWICK files for specifying clonal phylogenetic trees in cancer. SVEngine outpus alterred co...1384 days ago
maftools : Summarize, Analyze and Visualize MAF Files
With advances in Cancer Genomics, Mutation Annotation Format (MAF) is be...pted and used to store somatic variants detected. The Cancer Genome Atlas Project has sequenced over 30 different cancers with sample size of each can...1212 days ago
- With advances in Cancer Genomics, Mutation Annotation Format (MAF) is being widely accepted and used to store somatic variants detected. The Cancer Genome Atlas Project has sequenced over 30 different cancers with sample size of each can...
853 days ago
- To convert a VCF into a MAF, each variant must be mapped to only one of all possible gene transcripts/isoforms that it might affect. But even within a single isoform, a...
853 days ago
