Results for "cancer"

Tags

  • MAKER

    MAKER is a portable and easily configurable genome annotation pipeline.Its purpose is to allow smaller eukaryotic and prokaryotic genome projects to independently annotate their genomes and to create genome databases. MAKER identifies repeats, aligns ESTs and proteins to a genome, produces ab-ini...

    Tags: Bioinformatics, Computational Biology, Education, Cancer, Research, MAKER, Genome, Annotation, Pipeline, NGS, Assembly

    2972 days ago

  • BUSCO

    Assessing genome assembly and annotation completeness with Benchmarking Universal Single-Copy Orthologs More at http://busco.ezlab.org/

    Tags: Bioinformatics, Computational Biology, Education, Cancer, Research, BUSCO, Genome, Annotation, Pipeline, NGS, Assembly, Orthologs

    2972 days ago

  • RATT

    RATT is software to transfer annotation from a reference (annotated) genome to an unannotated query genome. It was first developed to transfer annotations between different genome assembly versions. However, it can also transfer annotations between strains and even different species, like Plasmo...

    Tags: Bioinformatics, Computational Biology, Education, Cancer, Research, RATT, Genome, Annotation, Pipeline, NGS, Assembly

    2972 days ago

  • COSMIC

    The accurate description and annotation of structural variants can be complex.  This is due to the different resolution that variants are reported from traditional cytogenetic coordinates down to the actual base pair positions. Furthermore, multiple rearrangements in a single area ...

    Tags: Bioinformatics, COSMIC, Chromosome, Cancer, Rearrangement, Breakpoints

    2735 days ago

  • Cancer Dependency Map

    The consequences of alterations in the DNA of cancer cells and subsequent vulnerabilities are not fully understood. This project aims to assign a dependency to every cancer cell in a patient which could be exploited to develop new therapies. This knowledge is foundational for precision cancer med...

    Tags: Cancer, Dependency, Map

    1505 days ago

  • Precision Medicine

    Coupling established clinical–pathological indexes with state-of-the-art molecular profiling to create diagnostic, prognostic, and therapeutic strategies precisely tailored to each patient's requirements — hence the term “Precision medicine”  Source:http://www.nejm.o...

    Tags: PrecisionMedicine, sequencing, genetics, genomics, molecularbiology, nanochips, medicine, cancer

    3869 days ago

  • Manta: rapid detection of structural variants and indels for germline and cancer sequencing applications.

    Manta calls structural variants (SVs) and indels from mapped paired-end sequencing reads. It is optimized for analysis of germline variation in small sets of individuals and somatic variation in tumor/normal sample pairs. Manta discovers, assembles and scores large-scale SVs, medium-sized indels ...

    Tags: Manta, rapid, detection, structural, variants, indels, germline, cancer, sequencing, applications

    2131 days ago

  • InfoGenomeR: Integrative reconstruction of cancer genome karyotypes

    InfoGenomeR is the Integrative Framework for Genome Reconstruction that uses a breakpoint graph to model the connectivity among genomic segments at the genome-wide scale. InfoGenomeR integrates cancer purity and ploidy, total CNAs, allele-specific CNAs, and haplotype information to identify the o...

    Tags: Integrative, reconstruction, cancer, genome, karyotypes, chromosome

    1058 days ago