Results for "gene"
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The bakers yeast, Saccharomyces cerevisiae is an ideal model organism to understand mechanisms of meiotic chromosome segregation. In S. cerevisiae and in mammals, the majority of meiotic crossovers are formed through a highly conserved MSH4p-MSH5p, MLH1p-MLH3p dependent pathway. We are interested...Tags: Bioinformatics, CrossOver, Recombination, Gene, Function, Genome, NGS, Sequences, CNV, Selection
2970 days ago
- TheLab seek to understand the genetic factors contributing to genomic variation and phenotypic diversity. To this end, we employ molecular and bioinformatic tools to study evolutionary processes at the level of populations, both experimental and natural, and genomes. Our research interests enco...
Tags: Bioinformatics, Duplication, Genome, Gene, Function, Population, NGS, Sequences, CNV, Selection
2980 days ago
- A major focus of our lab is understanding the effects of genetic variation on molecular phenotypes and human disease. We develop methods for integrating diverse functional genomic datasets of transcription, chromatin modifications, regulator binding, and their changes across multiple conditions t...
Tags: Variation and Disease, Genome Interpretation, Long non-coding RNAs, microRNAs, Gene, Epigenomics, Regulatory Motifs, Bio Networks, Evolution, Phylogenomics, Algorithms, Geometry/Vision, Robotics/AI.
3005 days ago
- The laboratory is focused on the discovery and analysis of structural variation (SVs) from genomic sequence data. As part of the 1000 Genomes Project and other endeavors, we have helped produce initial fine-scale maps using a variety of SV discovery approaches including: (i) paired-end mapping (o...
Tags: Bioinformatics, Gene, Epigenomics, Structure Variation, Deletion, Breakpoint, Chromosome
2981 days ago
- Horizontal gene transfer (HGT), the transfer of genetic material between organisms, is crucial for genetic innovation and the evolution of genome architecture. Existing HGT detection algorithms rely on a strong phylogenetic signal distinguishing the transferred sequence from ancestral (vertically...
Tags: Bioinformatics, NearHGT, Horizontal, Gene, Transfer, Haifa
2863 days ago
GeneValidator - Identify problems with predicted genes
GeneValidator helps in identifing problems with gene predictions and provide useful information extracted from analysing orthologs in BLAST databases. The results produced can be used by biocurators and researchers who need accurate gene predictions. If you would like to use GeneValidator on a f...Tags: Bioinformatics, Analysis, NGS, Gene, Prediction, GeneValidator, Genome
2798 days ago
- In this exercise, a previously annotated gene will be used to measure the accuracy of different gene finding approaches. GRAIL, GENSCAN, geneid, FGENESH, GenomeScan, GrailEXP and GENEWISE will be used to annotate the sequence. Both search by signal, content and homology (protein and cDNA seq...
Tags: Bioinformatics, Analysis, NGS, Gene, Prediction, Finding, Genome
2797 days ago
- Collections of few handy tools for bioinformatician http://molbiol-tools.ca/Convert.htm
Tags: Bioinformatics, Analysis, NGS, Tools, Gene, Genome, Format
2795 days ago
Prodigal (Prokaryotic Dynamic Programming Genefinding Algorithm)
Prodigal (Prokaryotic Dynamic Programming Genefinding Algorithm) is a microbial (bacterial and archaeal) gene finding program developed at Oak Ridge National Laboratory and the University of Tennessee. Key features of Prodigal include: Speed: Prodigal is an extremely fast gene r...Tags: Bioinformatics, Analysis, Gene, Prediction, Tool, Prodigal, Mathod
2673 days ago
DeCoSTAR - Detection of Co-evolution
DeCoSTAR is a software which aims at reconstructing ancestral gene or genome organizations, in the form of sets of neighborhood relations -adjacencies- between pairs of ancestral genes or gene domains.Ancestral genes or domains are deduced from reconciled gene trees in a context of birth, speciat...Tags: Bioinformatics, DeCoSTAR, Detection, Co-evolution, Reconstruction, Ancestral, Gene, Genome
2567 days ago
