Results for "genes"


  • Should you get sequenced? Not all bad genes predict disease

    “What we really don’t know yet is whether the predictive aspects of the genome are going to turn out to be beneficial or potentially harmful” “As we roll out genomic medicine we are fighting against this society-wide misconception that having the bad gene means you’...

    Tags: Sequencing, health, medicine, genes, disease

    1426 days ago

  • RCircos: an R package for Circos 2D track plots

    RCircos package provides a simple and flexible way to make Circos 2D track plots with R and could be easily integrated into other R data processing and graphic manipulation pipelines for presenting large-scale multi-sample genomic research data. It can also serve as a base tool to generate comple...

    Tags: Bioinformatics, NGS, R, Rcircos, Package, Plot, Circle, Genome, Genes, Visualization

    431 days ago

  • BioGPS

    A free extensible and customizable gene annotation portal, a complete resource for learning about gene and protein function.

    Tags: Bioinformatics, BioGPS, Genes, Prediction, Function

    429 days ago

  • clusterProfiler

    statistical analysis and visulization of functional profiles for genes and gene clustersBioconductor version: Release (3.3)This package implements methods to analyze and visualize functional profiles (GO and KEGG) of gene and gene clusters.Author: Guangchuang Yu <guangchuangyu at>...

    Tags: Bioinformatics, clusterProfiler, GO, R, Package, Omics, Genes, Cluster

    404 days ago

  • DarkHorse

    DarkHorse is a bioinformatic method for rapid, automated identification and ranking of phylogenetically atypical proteins on a genome-wide basis. It works by selecting potential ortholog matches from a reference database of amino acid sequences, then using these matches to calculate a lineag...

    Tags: Bioinformatics, HGT, Genes, Horizontal, Transfer, Method, Tools, DarkHorse

    399 days ago


    Gene finding in eukaryotic genomes is notoriously difficult to automate. The task is to design a work flow with a minimal set of tools that would reach state-of-the-art performance across a wide range of species. GeneMark-ET is a gene prediction tool that incorporates RNA-Seq data into unsupervis...

    Tags: Bioinformatics, Analysis, NGS, Braker, Annotation, Genes, Predictions, Genome

    328 days ago

  • GeneBreak

    Development of cancer is driven by somatic alterations, including numerical and structural chromosomal aberrations. Currently, several computational methods are available and are widely applied to detect numerical copy number aberrations (CNAs) of chromosomal segments in tumor genomes. However, t...

    Tags: Bioinformatics, GeneBreak, Chromosome, Genome, NGS, Breakpoints, Genes

    297 days ago

  • HybPiper

    HybPiper was designed for targeted sequence capture, in which DNA sequencing libraries are enriched for gene regions of interest, especially for phylogenetics. HybPiper is a suite of Python scripts that wrap and connect bioinformatics tools in order to extract target sequences from high-throughpu...

    Tags: Bioinformatics, Analysis, NGS, HybPiper, Genome, Network, Capture, Genes

    264 days ago

  • DAGchainer: Computing Chains of Syntenic Genes in Complete Genomes

    The DAGchainer software computes chains of syntenic genes found within complete genome sequences. As input, DAGchainer accepts a list of gene pairs with sequence homology along with their genome coordinates. Using a scoring function which accounts for the distance between neighboring genes on eac...

    Tags: Bioinformatics, DAGchainer, Computing, Chains, Syntenic, Genes, Genomes

    158 days ago

  • Enrichr: a comprehensive gene set enrichment analysis

    Enrichment analysis is a popular method for analyzing gene sets generated by genome-wide experiments. Here we present a significant update to one of the tools in this domain called Enrichr. Enrichr currently contains a large collection of diverse gene set libraries available for analysis and down...

    Tags: Bioinformatics, Analysis, Enrichment, Enrichr, Web, Server, GO, Pathway, Genes, BED, Ontologies, Drug, Cell, Disease

    90 days ago