Results for "horizontal"

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  • DarkHorse

    DarkHorse is a bioinformatic method for rapid, automated identification and ranking of phylogenetically atypical proteins on a genome-wide basis. It works by selecting potential ortholog matches from a reference database of amino acid sequences, then using these matches to calculate a lineag...

    Tags: Bioinformatics, HGT, Genes, Horizontal, Transfer, Method, Tools, DarkHorse

    2858 days ago

  • NearHGT

    Horizontal gene transfer (HGT), the transfer of genetic material between organisms, is crucial for genetic innovation and the evolution of genome architecture. Existing HGT detection algorithms rely on a strong phylogenetic signal distinguishing the transferred sequence from ancestral (vertically...

    Tags: Bioinformatics, NearHGT, Horizontal, Gene, Transfer, Haifa

    2858 days ago

  • Alien_Hunter : prediction of putative Horizontal Gene Transfer (HGT) events

    Alien_hunter is an application for the prediction of putative Horizontal Gene Transfer (HGT) events with the implementation of Interpolated Variable Order Motifs (IVOMs). An IVOM approach exploits compositional biases using variable order motif distributions and captures more reliably the local ...

    Tags: prediction, putative, Horizontal, Gene, Transfer, HGT, events, Alien, Hunter, Alien_hunter

    2293 days ago

  • HGT-Finder: A New Tool for Horizontal Gene Transfer Finding and Application to Aspergillus genomes

    HGT-Finder: (i) can be used for HGT detection in both prokaryotes and eukaryotes, (ii) can report a statistical P value for each gene to indicate how likely it is to be horizontally transferred, and (iii) is fully automated (requires minimal human intervention), as well as very ea...

    Tags: HGT-Finder, Tool, Horizontal, Gene, Transfer, Finding, Application, Aspergillus, genomes

    2284 days ago

  • alienness : Rapid Detection of Candidate Horizontal Gene Transfers across the Tree of Life

    Horizontal gene transfer (HGT) is the transmission of genes between organisms by other means than parental to offspring inheritance. While it is prevalent in prokaryotes, HGT is less frequent in eukaryotes and particularly in Metazoa. Here, we propose Alienness, a taxonomy-aware web application a...

    Tags: alienness, Rapid, Detection, Candidate, Horizontal, Gene, Transfers, Tree, Life

    2229 days ago

  • GeneMates: an R package for Detecting Horizontal Gene Co-transfer between Bacteria Using Gene-gene Associations Controlled for Population Structure

    GeneMates is an R package implementing a network approach to identify horizontal gene co-transfer (HGcoT) between bacteria using whole-genome sequencing (WGS) data. It is particularly useful for investigating intra-species HGcoT, where presence-absence status of acquired genes is usually confound...

    Tags: GeneMates, R, package, Horizontal, Gene, Co-transfer, Bacteria, Associations, Population, Structure

    1503 days ago

  • DarkHorse: a method for genome-wide prediction of horizontal gene transfer

    A new approach to rapid, genome-wide identification and ranking of horizontal transfer candidate proteins is presented. The method is quantitative, reproducible, and computationally undemanding. It can be combined with genomic signature and/or phylogenetic tree-building procedures to improve accu...

    Tags: DarkHorse, method, genome-wide, prediction, horizontal, gene, transfer, HGT

    2492 days ago

  • Bioinformatics tools to detect horizontal gene transfer (HGT) in genomes

    Horizontal gene transfer (HGT), the “non-sexual movement of genetic material between two organisms” , is relatively common in prokaryotes and single-celled eukaryotes, but a number of factors combine to make it far rarer in multicellular eukaryotes. In order for a eukaryotic spec...

    Tags: Tools, detect, horizontal, gene, transfer, HGT, genomes

    834 days ago

  • EuGI: a novel resource for studying genomic islands to facilitate horizontal gene transfer detection in eukaryotes

    SWGIS v2.0 along with the EuGI database, which houses GIs identified in 66 different eukaryotic species, and the EuGI web-resource, provide the first comprehensive resource for studying HGT in eukaryotes. https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-018-4724-8

    Tags: EuGI, novel, genomic, islands, facilitate, horizontal, gene, transfer, detection, eukaryotes, tools

    2168 days ago

  • HGTector: an automated method facilitating genome-wide discovery of putative horizontal gene transfers

    A computational pipeline for genome-wide detection of putative horizontal gene transfer (HGT) events based on sequence homology search hit distribution statistics Authors: Qiyun Zhu (qiyunzhu@gmail.com), Katharina Dittmar (katharinad@gmail.com) Affiliation: Department of Biological Sciences, Un...

    Tags: HGTector, automated, method, facilitating, genome-wide, discovery, putative, horizontal, gene, transfers

    1914 days ago