Results for "rearrangement"
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This software is designed to identify both simple and complex rearrangements from paired-end sequencing data. Users could ran it easily by just alling SVelter.py with proper parameters. It's also possible to ran it on multiple cores by calling different sub-functions separately. More a...Tags: Bioinformatics, Computational Biology, Svelter, Rearrangement
2971 days ago
- Destruct is a tool for joint prediction of rearrangement breakpoints from single or multiple tumour samples. More at https://bitbucket.org/dranew/destruct
Tags: Bioinformatics, Computational Biology, destruct, Rearrangement, Breakpoint
2971 days ago
- The accurate description and annotation of structural variants can be complex. This is due to the different resolution that variants are reported from traditional cytogenetic coordinates down to the actual base pair positions. Furthermore, multiple rearrangements in a single area ...
Tags: Bioinformatics, COSMIC, Chromosome, Cancer, Rearrangement, Breakpoints
2757 days ago
- Visualization has played an extremely important role in the current genomic revolution to inspect and understand variants, expression patterns, evolutionary changes, and a number of other relationships. However, most of the information in read-to-reference or genome-genome alignments is lost for ...
Tags: Bioinformatics, Analysis, NGS, Visualization, Genome, Rearrangement, Ribbon
2737 days ago
- Mauve is a system for constructing multiple genome alignments in the presence of large-scale evolutionary events such as rearrangement and inversion. Multiple genome alignments provide a basis for research into comparative genomics and the study of genome-wide evolutionary dynamics. Mauve has be...
Tags: Bioinformatics, Rearrangement, Mauve, Tool, Alignment
1955 days ago
Synteny and Rearrangement Identifier (SyRI)
SyRI is a comprehensive tool for predicting genomic differences between related genomes using whole-genome assemblies (WGA). The assemblies are aligned using whole-genome alignment tools, and these alignments are then used as input to SyRI. SyRI identifies syntenic path (longest set of co-linear ...Tags: Synteny, Rearrangement, Identifier, SyRI, Genome, Comparative, Genomics
1445 days ago
GRIDSS: the Genomic Rearrangement IDentification Software Suite
GRIDSS is a module software suite containing tools useful for the detection of genomic rearrangements. GRIDSS includes a genome-wide break-end assembler, as well as a structural variation caller for Illumina sequencing data. GRIDSS calls variants based on alignment-guided positional de Bruijn gra...Tags: GRIDSS, Genomic, Rearrangement, IDentification, Software, Suite
1433 days ago
- Chromosomal rearrangement events are caused by abnormal breaking and rejoining of DNA molecules. They are responsible for many of the cancer related diseases. Detecting the DNA breaking and repairing mechanism, therefore, may offer vital clues about the pathologic causes and diagnostic/therapeuti...
Tags: Chromosomal, rearrangement, events, abnormal, breaking, DNA, SLIDESORT-BPR
2342 days ago
SVfinder: Tool for detecting genomic rearrangement form DNA-seq data
SVfinder provides genome-wide detection of structural variants from next generation paired-end sequencing reads.Tags: SVfinder, Tool, detecting, genomic, rearrangement, DNA-seq
2318 days ago
Reference-free prediction of rearrangement breakpoint reads
lideSort-BPR ( b reak p oint r eads) is based on a fast algorithm for all-against-all comparisons of short reads and theoretical analyses of the number of neighboring reads. When applied to a dataset with a sequencing depth of 100×, it finds ∼88% of the bre...Tags: Reference-free, prediction, rearrangement, breakpoint, reads
2234 days ago
