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  • 5700 year-old human genome !

    ...wer was a female, most likely with dark skin, dark brown hair and blue eyes. https://www.nature.com/articles/s41467-019-13549-9 Artistic reconstruction. (Tom Björklund) More a...

    1583 days ago

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  • Sidow Lab

    We study mechanisms of cancer evolution by using state-of-the-art genomic approaches at the bench and in analysis. Accurate genome reconstruction is our other major area of interest. We a...

    1960 days ago

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  • DeCoSTAR - Detection of Co-evolution

    DeCoSTAR is a software which aims at reconstructing ancestral gene or genome organizations, in the form of sets of neighborhood relations -adjacencies- between pairs of ancestral genes or gene domains.Ancestral genes or domains are deduced from reconciled gene trees in a context of birth, speciat...

    Tags: Bioinformatics, DeCoSTAR, Detection, Co-evolution, Reconstruction, Ancestral, Gene, Genome

    2563 days ago

  • CAR: Reconstructing Contiguous Regions of an Ancestral Genome

    We describe a new method for predicting the ancestral order and orientation of those intervals from their observed adjacencies in modern species. We combine the results from this method with data from chromosome painting experiments to produce a map of an early mammalian genome that accounts fo...

    Tags: Reconstruction, Contiguous, Regions, Ancestral, Genome, Bioinformatics, CAR

    2529 days ago

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