Sequencing Solutions to World Health
"New technology that quickly, easily and economically reveals the genomes of viruses and pathogens transforms public health and medicine." Source: Life technologiesTags: Sequencing, virus, pathogen, health, medicine
3865 days ago
Should you get sequenced? Not all bad genes predict disease
“What we really don’t know yet is whether the predictive aspects of the genome are going to turn out to be beneficial or potentially harmful” “As we roll out genomic medicine we are fighting against this society-wide misconception that having the bad gene means you’...Tags: Sequencing, health, medicine, genes, disease
3865 days ago
Comparison of Short Read De Novo Alignment Algorithms
Excellent article to introduce different sequencing methods along with tools for de novo assembly of sequencing reads and their relevant references. Title: Comparison of Short Read De Novo Alignment Algorithms Author: Nikhil GopalTags: Sequencing, assembly, de novo assembly, velvet
3873 days ago
Latest paper on comparison of mapping tools
A. Hatem, D. Bozdag, A. E. Toland, U. V. Catalyurek "Benchmarking short sequence mapping tools" BMC Bioinformatics, 14(1):184, 2013. http://bmi.osu.edu/hpc/software/benchmark/ http://bmi.osu.edu/hpc/software/pmap/pmap.html Other similiar papers: http://online.liebertpub.com/doi/pdf/10.1089/cm...Tags: Sequencing, short reads mapping, SNP, GSNAP, BWA, Bowtie, BWA, mrsFAST
3860 days ago
Encode sequencing data freely available to download and use for academic means
In Encode, regulatory elements investigated via DNA hypersensitivity assays, assays of DNA methylation, and chromatin immunoprecipitation (ChIP) of proteins that interact with DNA, including modified histones and transcription factors, followed by sequencing (ChIP-Seq). More information: h...Tags: Encode, UCSC, genome browser, Sequencing, RNA-Seq, Chip-Seq, Epigenomics, Methylation, histone modification, regulatory elements, HMM
3669 days ago
Tags: Sequencing, conifer, genome assembly, plant
3661 days ago
Tags: Sequencing, RNA-Seq
3626 days ago
GraphMap - A highly sensitive and accurate mapper for long, error-prone reads
GraphMap is a novel mapper targeted at aligning long, error-prone third-generation sequencing data.It is designed to handle Oxford Nanopore MinION 1d and 2d reads with very high sensitivity and accuracy, and also presents a significant improvement over the state-of-the-art for PacBio re...Tags: Nanopore, Sequencing, GraphMap, MinION. NGS
3188 days ago
Scaffolding of a bacterial genome using MinION nanopore sequencing
Second generation sequencing has revolutionized genomic studies. However, most genomes contain repeated DNA elements that are longer than the read lengths achievable with typical sequencers, so the genomic order of several generated contigs cannot be easily resolved. A new generation of sequencer...Tags: Nanopore, Sequencing, Technology, NGS
3188 days ago
Tags: Bioinformatics, Cutadapt, NGS, Reads, Fastq, Sequencing
2877 days ago