<![CDATA[BOL: All site questions]]> https://bioinformaticsonline.com/answers/?offset=140 https://bioinformaticsonline.com/answers/view/22346/how-does-the-3d-genome-technology-works Wed, 20 May 2015 14:48:17 -0500 https://bioinformaticsonline.com/answers/view/22346/how-does-the-3d-genome-technology-works <![CDATA[How does the 3D genome technology works?]]> There are many techniques available to enquire about the oganization of the nucleus. I am keenly interested to know the basic machanism behind it. I mean how does it works?

]]> Rahul Nayak https://bioinformaticsonline.com/answers/view/21917/tel-me-any-software-which-draw-ligand-and-gives-output-in-the-pdb-format Mon, 06 Apr 2015 05:33:26 -0500 https://bioinformaticsonline.com/answers/view/21917/tel-me-any-software-which-draw-ligand-and-gives-output-in-the-pdb-format <![CDATA[Tel me any software which draw ligand and gives output in the PDB format ?]]> PDB Ligand is reqiured for flexible protein docking 

]]> Tayyba Kamran https://bioinformaticsonline.com/answers/view/21909/is-there-any-article-related-to-3d-structure-prediction-of-any-enzyme-of-protein-by-abinitio-methods-using-swiss-model-cph-or-other-servers-like-geno3d Sat, 04 Apr 2015 06:05:46 -0500 https://bioinformaticsonline.com/answers/view/21909/is-there-any-article-related-to-3d-structure-prediction-of-any-enzyme-of-protein-by-abinitio-methods-using-swiss-model-cph-or-other-servers-like-geno3d <![CDATA[is there any article related to 3D structure prediction of any enzyme of protein by abinitio methods using swiss model, CPH, or other servers like Geno3D]]> Nadia Baig https://bioinformaticsonline.com/answers/view/21713/what-are-some-important-proteins-whose-3d-structure-is-not-predicted-yet Wed, 18 Mar 2015 13:04:59 -0500 https://bioinformaticsonline.com/answers/view/21713/what-are-some-important-proteins-whose-3d-structure-is-not-predicted-yet <![CDATA[What are some important proteins whose 3D structure is not predicted yet??]]> Nadia Baig https://bioinformaticsonline.com/answers/view/21669/manual-pharmacophore-designing Fri, 13 Mar 2015 21:06:32 -0500 https://bioinformaticsonline.com/answers/view/21669/manual-pharmacophore-designing <![CDATA[manual pharmacophore designing]]> Can we design a pharmacophore model manually ? please some one help me...thank you

]]> pinke https://bioinformaticsonline.com/answers/view/21455/how-can-i-downlod-microarray-time-series-data-in-spreed-sheet Fri, 27 Feb 2015 01:04:12 -0600 https://bioinformaticsonline.com/answers/view/21455/how-can-i-downlod-microarray-time-series-data-in-spreed-sheet <![CDATA[How can I downlod microarray time series data in spreed sheet?]]> I need some help plz!!
I am a Newbie in this area, and I wanna apply to microarray univarate & multivarite time series.

thanx in advance

]]> Randa https://bioinformaticsonline.com/answers/view/21359/learn-r-by-yourself Thu, 19 Feb 2015 19:37:48 -0600 https://bioinformaticsonline.com/answers/view/21359/learn-r-by-yourself <![CDATA[Learn R by yourself?]]> Hi. I m a new to R and biostatistics. Do you think is possible to learn R by yourself? Can you recommend me some book or same web site for that? Thank you very much!

]]> Manshi Raghubanshi https://bioinformaticsonline.com/answers/view/21183/is-it-possible-to-find-out-the-site-of-expressed-protein-with-the-use-of-respective-gene-sequence Thu, 12 Feb 2015 05:40:09 -0600 https://bioinformaticsonline.com/answers/view/21183/is-it-possible-to-find-out-the-site-of-expressed-protein-with-the-use-of-respective-gene-sequence <![CDATA[Is it possible to find out the site of expressed protein with the use of respective gene sequence?]]> Is it possible to find out the site of expressed protein with the use of respective gene sequence? Could we able to detect the signal peptide or signal sequence coding region from gene sequence or mRNA sequence?Is there any database or source where we can find signal peptide sequence and there projected location for attached protein with respect to different organisms?

A signal peptide (sometimes referred to as signal sequence, targeting signals, localization signals, localization sequence, transit peptides leader sequence or leader peptide) is a short (5-30 amino acids long) peptide present at the N-terminus of the majority of newly synthesized proteins that are destined towards the secretory pathway.These proteins include those that reside either inside certain organelles (the endoplasmic reticulum, golgi or endosomes), secreted from the cell, or inserted into most cellular membranes. Although most type I membrane-bound proteins have signal peptides, the majority of type II and multi-spanning membrane-bound proteins are targeted to the secretory pathway by their first transmembrane domain, which biochemically resembles a signal sequence except that it is not cleaved.In vertebrates, the region of the mRNA that codes for the signal peptide (i.e. the signal sequence coding region, or SSCR) can function as an RNA element with specific activities.

But I need information or data related to all the organisms(i.e.prokaryotic and eukaryotic)signal peptides and their predicted location.Or it will detect the signal sequence coding region from given gene sequence to predict the location of expressed protein.

]]> Swapnil Bhalke https://bioinformaticsonline.com/answers/view/21023/could-someone-suggest-a-tutorial-or-a-book-for-the-ngs-analysis Fri, 06 Feb 2015 04:32:41 -0600 https://bioinformaticsonline.com/answers/view/21023/could-someone-suggest-a-tutorial-or-a-book-for-the-ngs-analysis <![CDATA[Could someone suggest a tutorial or a book for the NGS analysis?]]> Archana Choudhary https://bioinformaticsonline.com/answers/view/20671/bioinformatics-study-partner Thu, 29 Jan 2015 11:44:12 -0600 https://bioinformaticsonline.com/answers/view/20671/bioinformatics-study-partner <![CDATA[bioinformatics study partner]]> need a bioinformatics study partner for discussing and working on different areas in the field , my details : 

email : karimse07@yahoo.com

skype : karimse07

anyone interested ? 

]]> karimse07