BOL: All site questions

What is Big-O Notation ?

Surabhi Chaudhary — Mon, 25 Aug 2014 16:50:06 -0500

Hi All,

I am currectly focusing on algorithmic section of computational biology. I came across Big-O Notation in a research paper which made my head hurt. I google it but unable to understand it. I appreciate any help to get rid of my confusion. Any practical examples and a proper explanation of this would really help.

Thanks

A script to convert Ensembl, Unigene, Uniprot and RefSeq IDs to Symbol IDs

Neel — Sun, 10 Aug 2014 13:53:01 -0500

Hello, I am looking for a program/function that converts different sources of IDs to Symbol IDs. The script in R will be an added advantage ...

Thanks

How to install and work with local blast??

Nandhini devi — Fri, 08 Aug 2014 06:14:46 -0500

Hi! I have downloaded the latest version of blast+ from the FTP site. I know upto changing the directory and it came to bin.. How can i run the sequences? I read user manual but i cant understood.. help me

Is there any quick way to replace an existing substring with a new substring in a string?

Suleman Khan — Thu, 07 Aug 2014 17:23:01 -0500

I am currently using a s/// regex like this: $str =~ s/$find/$replace/g;

Looking for some other quicker way for the same.

Thanks

Can anyone tell me the clear procedure for new or novel miRNA identification in animal??

Nandhini devi — Thu, 07 Aug 2014 04:13:43 -0500

Hi!

Currently i am working in miRNA identification based on EST of particular animal.. i did blastn search against the EST to identify the homologous of mature miRNA.. Next step is blastx to remove the protein coding sequences. How can i select the non-coding transcripts or EST's from those results? On what criteria i have to select?? Then I want to know how to select the range of precursors and mature miRNA? Based on secondary structure means how they find the mature miRNA? I read many articles but i am still not clear how to find those.. If anyone know plz help me..

Thanks,

Nandhini

What are the differences between Bioinformatics and Computational Biology?

Ashwin Mishra — Wed, 23 Jul 2014 08:43:57 -0500

I have visited many websites but still unable to clearly distinguish them.

What are the best known workflow or tutorial for SNP calling?

Neel — Sat, 12 Jul 2014 15:39:52 -0500

What does the overlapping criteria in epiexplorer mean , and can i predict if the expression would be affected after uploading the data and knowing the overlap %.?

heba — Sun, 22 Jun 2014 03:43:08 -0500

How can I convert .pdb/smiles/.mol files into .mae format?

pinke — Fri, 20 Jun 2014 07:42:51 -0500

How can I convert .pdb/smiles/.mol files into .mae format by using schrodinger software in windows OS (2009 version). I tried to do it with open bable, but im unable to find .mae format in openbable. please somebody help me.

thank you

Can you please recommend me some tutorial for NGS data analysis?

Alok Prajapati — Fri, 20 Jun 2014 02:57:56 -0500

Hi Bioinformatician,

I am newbie bioinformatician interested in knowing something more about next generation sequencing (NGS) and learn to interpret the data obtained from these technologies. In particular I want to know what kind of analyses is possible to perform on these data and what kind of tools can be used to achieve results. Other needs:

Where can I find information or a tutorial?

Does anyone know where I could start?

Any good book, website, tutorial are welcome?

Thanks for your time.

Thanks