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<channel>
	<title><![CDATA[BOL: All site bookmarks]]></title>
	<link>https://bioinformaticsonline.com/bookmarks/all?offset=500</link>
	<atom:link href="https://bioinformaticsonline.com/bookmarks/all?offset=500" rel="self" type="application/rss+xml" />
	<description><![CDATA[]]></description>
	
	<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/39200/omtools-a-software-package-for-visualizing-and-processing-optical-mapping-data</guid>
	<pubDate>Fri, 29 Mar 2019 01:21:54 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/39200/omtools-a-software-package-for-visualizing-and-processing-optical-mapping-data</link>
	<title><![CDATA[OMTools: a software package for visualizing and processing optical mapping data]]></title>
	<description><![CDATA[<p><span>OMTools, an efficient and intuitive data processing and visualization suite to handle and explore large-scale optical mapping profiles. OMTools includes modules for visualization (OMView), data processing and simulation. These modules together form an accessible and convenient pipeline for optical mapping analyses.</span></p>
<p><span><a href="https://github.com/TF-Chan-Lab/OMTools">https://github.com/TF-Chan-Lab/OMTools</a></span></p><p>Address of the bookmark: <a href="https://github.com/TF-Chan-Lab/OMTools" rel="nofollow">https://github.com/TF-Chan-Lab/OMTools</a></p>]]></description>
	<dc:creator>BioJoker</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/39190/chipulate-a-python3-framework-to-simulate-read-counts-in-a-chip-seq-experiment</guid>
	<pubDate>Mon, 25 Mar 2019 12:46:47 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/39190/chipulate-a-python3-framework-to-simulate-read-counts-in-a-chip-seq-experiment</link>
	<title><![CDATA[ChIPulate: A Python3 framework to simulate read counts in a ChIP-seq experiment]]></title>
	<description><![CDATA[<p><span style="color: #202020; font-size: 13px; font-style: normal; font-weight: 400; text-align: start; background-color: #ffffff; float: none;">ChIP-seq simulation pipeline, ChIPulate, we assess the impact of various biological and experimental sources of variation on several outcomes of a ChIP-seq experiment, viz., the recoverability of the TF binding motif, accuracy of TF-DNA binding detection, the sensitivity of inferred TF-DNA binding strength, and number of replicates needed to confidently infer binding strength.<span> <br></span></span></p><p>Address of the bookmark: <a href="https://github.com/vishakad/chipulate" rel="nofollow">https://github.com/vishakad/chipulate</a></p>]]></description>
	<dc:creator>Abhimanyu Singh</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/39187/distruct-a-program-for-the-graphical-display-of-population-structure</guid>
	<pubDate>Mon, 25 Mar 2019 03:33:44 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/39187/distruct-a-program-for-the-graphical-display-of-population-structure</link>
	<title><![CDATA[DISTRUCT: a program for the graphical display of population structure]]></title>
	<description><![CDATA[<p><em>distruct</em><span>&nbsp;is a program that can be used to graphically display results produced by the genetic clustering program&nbsp;</span><em><a href="http://pritch.bsd.uchicago.edu/">structure</a></em><span>&nbsp;or by other similar programs. The figures produced by&nbsp;</span><em>distruct</em><span>display individual membership coefficients in the same form as used in&nbsp;</span><a href="https://rosenberglab.stanford.edu/papers/popstruct.pdf">"Genetic structure of human populations"&nbsp;<em>Science</em>&nbsp;298: 2381-2385 (2002)</a><span>. Various options enable the user to control left-to-right printing order of populations, bottom-to-top printing order of clusers, colors, and other graphical details. [</span><a href="https://rosenberglab.stanford.edu/distructExample.html">Example</a><span>]</span></p>
<p>[<a href="https://rosenberglab.stanford.edu/distructForms/distructRegistration.html">Download software package (includes the manual)</a>] (you will be directed first to a registration page and we would very much appreciate if you register)&nbsp;<br>[<a href="https://rosenberglab.stanford.edu/software/distructManual.pdf">Download manual</a>]&nbsp;<br>[<a href="https://rosenberglab.stanford.edu/papers/distructNote.pdf">Download software note from&nbsp;<em>Molecular Ecology Notes</em>&nbsp;4: 137-138 (2004)</a>]</p>
<p>To use the UNIX versions, unzip and untar the files in an appropriate directory using</p>
<pre>gunzip filename.tar.gz; tar xvf filename.tar</pre>
<p><span>where "filename.tar.gz" is the downloaded file. Winzip will unzip the Windows version. Run the program by typing</span></p>
<pre>./distruct</pre>
<p><span>in UNIX or</span></p>
<pre>distruct</pre>
<p><span>from a Dos prompt in Windows. It will produce a figure using the data that are represented in the Central/South Asia&nbsp;</span><em>K=5</em><span>&nbsp;plot in&nbsp;</span><em>Science</em><span>&nbsp;298: 2381-2385 (2002).</span></p>
<p>Please send comments or problems with&nbsp;<em>distruct</em>&nbsp;to Noah Rosenberg.</p>
<h4><em>October 15, 2014 &mdash; Users of Distruct may also find&nbsp;<a href="https://rosenberglab.stanford.edu/clumpp.html">CLUMPP</a>&nbsp;and&nbsp;<a href="http://clumpak.tau.ac.il/">CLUMPAK</a>&nbsp;of interest.</em></h4><p>Address of the bookmark: <a href="https://rosenberglab.stanford.edu/distruct.html" rel="nofollow">https://rosenberglab.stanford.edu/distruct.html</a></p>]]></description>
	<dc:creator>Abhimanyu Singh</dc:creator>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/39114/plumberan-r-package-that-converts-your-existing-r-code-to-a-web-api</guid>
	<pubDate>Wed, 13 Mar 2019 19:20:10 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/39114/plumberan-r-package-that-converts-your-existing-r-code-to-a-web-api</link>
	<title><![CDATA[plumber:An R package that converts your existing R code to a web API]]></title>
	<description><![CDATA[<p>plumber allows you to create a REST API by merely decorating your existing R source code with special comments. Take a look at an example.</p>
<pre><code><span># plumber.R
</span><span>
</span><span>#* Echo back the input
#* @param msg The message to echo
#* @get /echo
</span><span>function</span><span>(</span><span>msg</span><span>=</span><span>""</span><span>){</span><span>
  </span><span>list</span><span>(</span><span>msg</span><span> </span><span>=</span><span> </span><span>paste0</span><span>(</span><span>"The message is: '"</span><span>,</span><span> </span><span>msg</span><span>,</span><span> </span><span>"'"</span><span>))</span><span>
</span><span>}</span><span>

</span><span>#* Plot a histogram
#* @png
#* @get /plot
</span><span>function</span><span>(){</span><span>
  </span><span>rand</span><span> </span><span>&lt;-</span><span> </span><span>rnorm</span><span>(</span><span>100</span><span>)</span><span>
  </span><span>hist</span><span>(</span><span>rand</span><span>)</span><span>
</span><span>}</span><span>

</span><span>#* Return the sum of two numbers
#* @param a The first number to add
#* @param b The second number to add
#* @post /sum
</span><span>function</span><span>(</span><span>a</span><span>,</span><span> </span><span>b</span><span>){</span><span>
  </span><span>as.numeric</span><span>(</span><span>a</span><span>)</span><span> </span><span>+</span><span> </span><span>as.numeric</span><span>(</span><span>b</span><span>)</span><span>
</span><span>}</span></code></pre><p>Address of the bookmark: <a href="https://www.rplumber.io/" rel="nofollow">https://www.rplumber.io/</a></p>]]></description>
	<dc:creator>BioJoker</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/39104/hipstr-haplotype-inference-and-phasing-for-short-tandem-repeats</guid>
	<pubDate>Thu, 07 Mar 2019 21:13:06 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/39104/hipstr-haplotype-inference-and-phasing-for-short-tandem-repeats</link>
	<title><![CDATA[HipSTR: Haplotype inference and phasing for Short Tandem Repeats]]></title>
	<description><![CDATA[<p><span>HipSTR</span>&nbsp;was specifically developed to deal with these errors in the hopes of obtaining more robust STR genotypes. In particular, it accomplishes this by:</p>
<ol>
<li>Learning locus-specific PCR stutter models using an&nbsp;<a href="http://en.wikipedia.org/wiki/Expectation-maximization_algorithm">EM algorithm</a></li>
<li>Mining candidate STR alleles from population-scale sequencing data</li>
<li>Employing a specialized hidden Markov model to align reads to candidate alleles while accounting for STR artifacts</li>
<li>Utilizing phased SNP haplotypes to genotype and phase STRs</li>
</ol><p>Address of the bookmark: <a href="https://github.com/tfwillems/HipSTR" rel="nofollow">https://github.com/tfwillems/HipSTR</a></p>]]></description>
	<dc:creator>BioJoker</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/39098/sda-long-read-sequence-and-assembly-of-segmental-duplications</guid>
	<pubDate>Tue, 05 Mar 2019 10:00:57 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/39098/sda-long-read-sequence-and-assembly-of-segmental-duplications</link>
	<title><![CDATA[SDA: Long-read sequence and assembly of segmental duplications]]></title>
	<description><![CDATA[<p><span><span>Segmental Duplication Assembler (SDA; https://github.com/mvollger/SDA) constructs graphs in which paralogous sequence variants define the nodes and long-read sequences provide attraction and repulsion edges, enabling the partition and assembly of long reads corresponding to distinct paralogs.<br></span></span></p>
<p><span><span>https://github.com/mvollger/SDA</span></span></p><p>Address of the bookmark: <a href="https://www.nature.com/articles/s41592-018-0236-3" rel="nofollow">https://www.nature.com/articles/s41592-018-0236-3</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/39039/dotplotly-generate-an-interactive-dot-plot-from-mummer-or-minimap-alignments</guid>
	<pubDate>Thu, 21 Feb 2019 10:22:17 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/39039/dotplotly-generate-an-interactive-dot-plot-from-mummer-or-minimap-alignments</link>
	<title><![CDATA[dotPlotly: Generate an interactive dot plot from mummer or minimap alignments]]></title>
	<description><![CDATA[<p>Create an interactive dot plot from mummer output OR PAF format</p>
<p>R script that makes a plotly interactive and/or static (png/pdf) dot plot.</p>
<p><a href="https://tom-poorten.shinyapps.io/dotplotly_shiny/">Shiny app available for testing</a></p><p>Address of the bookmark: <a href="https://github.com/tpoorten/dotPlotly" rel="nofollow">https://github.com/tpoorten/dotPlotly</a></p>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/39019/iq-tree-efficient-software-for-phylogenomic-inference</guid>
	<pubDate>Mon, 18 Feb 2019 04:25:11 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/39019/iq-tree-efficient-software-for-phylogenomic-inference</link>
	<title><![CDATA[IQ-TREE: Efficient software for phylogenomic inference]]></title>
	<description><![CDATA[<p><span>A fast and effective stochastic algorithm to infer phylogenetic trees by maximum likelihood.&nbsp;</span><em>IQ-TREE compares favorably to RAxML and PhyML</em><span>&nbsp;in terms of likelihoods with similar computing time</span></p>
<p><span><span>IQ-TREE found higher likelihoods between 62.2% and 87.1% of the studied alignments, thus efficiently exploring the tree-space. If we use the IQ-TREE stopping rule, RAxML and PhyML are faster in 75.7% and 47.1% of the DNA alignments and 42.2% and 100% of the protein alignments, respectively. However, the range of obtaining higher likelihoods with IQ-TREE improves to 73.3&ndash;97.1%. IQ-TREE is freely available at&nbsp;</span><a href="http://www.cibiv.at/software/iqtree" target="">http://www.cibiv.at/software/iqtree</a></span></p><p>Address of the bookmark: <a href="http://www.iqtree.org/" rel="nofollow">http://www.iqtree.org/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/39017/macse-multiple-alignment-of-coding-sequences-accounting-for-frameshifts-and-stop-codons</guid>
	<pubDate>Mon, 18 Feb 2019 04:21:50 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/39017/macse-multiple-alignment-of-coding-sequences-accounting-for-frameshifts-and-stop-codons</link>
	<title><![CDATA[MACSE: Multiple Alignment of Coding SEquences Accounting for Frameshifts and Stop Codons]]></title>
	<description><![CDATA[<p>MACSE aligns coding NT sequences with respect to their AA translation while allowing NT sequences to contain multiple frameshifts and/or stop codons. MACSE is hence the first automatic solution to align protein-coding gene datasets containing non-functional sequences (pseudogenes) without disrupting the underlying codon structure. It has also proved useful in detecting undocumented frameshifts in public database sequences and in aligning next-generation sequencing reads/contigs against a reference coding sequence.</p>
<p>For further details about the underlying algorithm see the original publication:<br><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0022594" target="_new">MACSE: Multiple Alignment of Coding SEquences accounting for frameshifts and stop codons.<br>Vincent Ranwez, S&eacute;bastien Harispe, Fr&eacute;d&eacute;ric Delsuc, Emmanuel JP Douzery<br>PLoS One 2011, 6(9): e22594</a>.</p><p>Address of the bookmark: <a href="https://bioweb.supagro.inra.fr/macse/index.php?menu=releases" rel="nofollow">https://bioweb.supagro.inra.fr/macse/index.php?menu=releases</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/38908/busca-an-integrative-web-server-to-predict-subcellular-localization-of-proteins</guid>
	<pubDate>Thu, 07 Feb 2019 14:08:11 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/38908/busca-an-integrative-web-server-to-predict-subcellular-localization-of-proteins</link>
	<title><![CDATA[BUSCA: an integrative web server to predict subcellular localization of proteins]]></title>
	<description><![CDATA[<p><span>BUSCA (Bologna Unified Subcellular Component Annotator) is a web-server for predicting protein subcellular localization. BUSCA integrates different tools to predict localization-related protein features (DeepSig, TPpred3, PredGPI and ENSEMBLE3.0) as well as tools for discriminating subcellular localization of both globular and membrane proteins (BaCelLo, MemLoci and SChloro).</span></p><p>Address of the bookmark: <a href="http://busca.biocomp.unibo.it/" rel="nofollow">http://busca.biocomp.unibo.it/</a></p>]]></description>
	<dc:creator>BioStar</dc:creator>
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