<![CDATA[BOL: EXCAVATOR2tool]]> https://bioinformaticsonline.com/bookmarks/view/30002/excavator2tool? https://bioinformaticsonline.com/bookmarks/view/30002/excavator2tool Wed, 30 Nov 2016 04:09:19 -0600 https://bioinformaticsonline.com/bookmarks/view/30002/excavator2tool <![CDATA[EXCAVATOR2tool]]> EXCAVATOR2 is a collection of bash, R and Fortran scripts and codes that analyses Whole Exome Sequencing (WES) data to identify CNVs. EXCAVATOR2 enhances the identification of all genomic CNVs, both overlapping and non-overlapping targeted exons by integrating the analysis of In-targets and Off- targets reads. Specifically, it improves the precision of calling CNVs overlapping targeted exons from WES data and enlarges the spectrum of detectable CNVs to off-target events.
EXCAVATOR2 can be effectively employed for the identification of CNVs in small as well as large-scale re-sequencing population and cancer studies. Lastly, it’s of particular interest that all WES experiments can be re-analysed using our method with the beneficial effect to identify novelCNVs in extra-exonic regions by having the full-genome CN profile.

Address of the bookmark: https://sourceforge.net/projects/excavator2tool/

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