<![CDATA[BOL: GAM-NGS: genomic assemblies merger for next generation sequencing]]> https://bioinformaticsonline.com/bookmarks/view/30207/gam-ngs-genomic-assemblies-merger-for-next-generation-sequencing? https://bioinformaticsonline.com/bookmarks/view/30207/gam-ngs-genomic-assemblies-merger-for-next-generation-sequencing Mon, 19 Dec 2016 06:07:05 -0600 https://bioinformaticsonline.com/bookmarks/view/30207/gam-ngs-genomic-assemblies-merger-for-next-generation-sequencing <![CDATA[GAM-NGS: genomic assemblies merger for next generation sequencing]]> GAM-NGS (Genomic Assemblies Merger for Next Generation Sequencing), whose primary goal is to merge two or more assemblies in order to enhance contiguity and correctness of both. GAM-NGS does not rely on global alignment: regions of the two assemblies representing the same genomic locus (called blocks) are identified through reads' alignments and stored in a weightedgraph. The merging phase is carried out with the help of this weighted graph that allows an optimal resolution of local problematic regions.

Address of the bookmark: https://github.com/vice87/gam-ngs

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