<![CDATA[BOL: YASRA: Reference based assembler]]> https://bioinformaticsonline.com/bookmarks/view/31205/yasra-reference-based-assembler? https://bioinformaticsonline.com/bookmarks/view/31205/yasra-reference-based-assembler Wed, 01 Mar 2017 08:32:45 -0600 https://bioinformaticsonline.com/bookmarks/view/31205/yasra-reference-based-assembler <![CDATA[YASRA: Reference based assembler]]> YASRA (Yet Another Short Read Assembler) performs comparative assembly of short reads using a reference genome, which can differ substantially from the genome being sequenced. Mapping reads to reference genomes makes use of LASTZ (Harris et al), a pairwise sequence aligner compatible with BLASTZ. Special scoring sets were derived to improve the performance, both in runtime and quality for 454 and Illumina sequence reads.

YASRA uses LASTZ (http://bx.psu.edu/miller_lab for released version and http://www.bx.psu.edu/~rsharris/lastz/newer for newer version) for aligning the sequences to the reference genome. Please install LASTZ (the newest version on http://www.bx.psu.edu/~rsharris/lastz/newer) and add the LASTZ binary in your executable/binary search path before installing YASRA.

Address of the bookmark: https://github.com/aakrosh/YASRA

]]> Abhimanyu Singh