<![CDATA[BOL: Flye: Fast and accurate de novo assembler for single molecule sequencing reads]]> https://bioinformaticsonline.com/bookmarks/view/36476/flye-fast-and-accurate-de-novo-assembler-for-single-molecule-sequencing-reads? https://bioinformaticsonline.com/bookmarks/view/36476/flye-fast-and-accurate-de-novo-assembler-for-single-molecule-sequencing-reads Fri, 04 May 2018 19:16:22 -0500 https://bioinformaticsonline.com/bookmarks/view/36476/flye-fast-and-accurate-de-novo-assembler-for-single-molecule-sequencing-reads <![CDATA[Flye: Fast and accurate de novo assembler for single molecule sequencing reads]]> Flye is a de novo assembler for long and noisy reads, such as those produced by PacBio and Oxford Nanopore Technologies. The algorithm uses an A-Bruijn graph to find the overlaps between reads and does not require them to be error-corrected. After the initial assembly, Flye performs an extra repeat classification and analysis step to improve the structural accuracy of the resulting sequence. The package also includes a polisher module, which produces the final assembly of high nucleotide-level quality.

Address of the bookmark: https://github.com/fenderglass/Flye

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