<![CDATA[BOL: LACHESIS: Genome Assembly with Hi-C-based Contact Probability Maps (LACHESIS)]]> https://bioinformaticsonline.com/bookmarks/view/36592/lachesis-genome-assembly-with-hi-c-based-contact-probability-maps-lachesis? https://bioinformaticsonline.com/bookmarks/view/36592/lachesis-genome-assembly-with-hi-c-based-contact-probability-maps-lachesis Mon, 14 May 2018 04:26:30 -0500 https://bioinformaticsonline.com/bookmarks/view/36592/lachesis-genome-assembly-with-hi-c-based-contact-probability-maps-lachesis <![CDATA[LACHESIS: Genome Assembly with Hi-C-based Contact Probability Maps (LACHESIS)]]> LACHESIS is method that exploits contact probability map data (e.g. from Hi-C) for chromosome-scale de novo genome assembly.

Further information about LACHESIS, including source code, documentation and a user's guide are available at: http://shendurelab.github.io/LACHESIS.

Manuscript describing LACHESIS was published as: Burton JN#, Adey A, Patwardhan RP, Qiu R, Kitzman JO, Shendure J#. Chromosome-scale scaffolding of de novo genome assemblies based on chromatin interactions. Nature Biotechnology 2013 Dec;31(12):1119-25. doi: 10.1038/nbt.272. PubMed PMID: 24185095.

 

http://shendurelab.github.io/LACHESIS/

Address of the bookmark: http://shendurelab.github.io/LACHESIS/

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