<![CDATA[BOL: Darwin-WGA: A Co-processor Provides Increased Sensitivity in Whole Genome Alignments with High Speedup]]> https://bioinformaticsonline.com/bookmarks/view/39250/darwin-wga-a-co-processor-provides-increased-sensitivity-in-whole-genome-alignments-with-high-speedup? https://bioinformaticsonline.com/bookmarks/view/39250/darwin-wga-a-co-processor-provides-increased-sensitivity-in-whole-genome-alignments-with-high-speedup Sat, 13 Apr 2019 08:55:31 -0500 https://bioinformaticsonline.com/bookmarks/view/39250/darwin-wga-a-co-processor-provides-increased-sensitivity-in-whole-genome-alignments-with-high-speedup <![CDATA[Darwin-WGA: A Co-processor Provides Increased Sensitivity in Whole Genome Alignments with High Speedup]]> Darwin-WGA, is the first hardware accelerator for whole genome alignment and accelerates the gapped filtering stage. Darwin-WGA also employs GACT-X, a novel algorithm used in the extension stage to align arbitrarily long genome sequences using a small on-chip memory, that provides better quality alignments at 2× improvement in memory and speed over the previously published GACT algorithm. Implemented on an FPGA, Darwin-WGA provides up to 24× improvement (performance/$) in WGA over iso-sensitive software.

https://stanford.edu/~yatisht/pubs/darwin-wga.pdf

Address of the bookmark: https://github.com/gsneha26/Darwin-WGA

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