<![CDATA[BOL: HumCFS: a database of fragile sites in human chromosomes]]> https://bioinformaticsonline.com/bookmarks/view/39281/humcfs-a-database-of-fragile-sites-in-human-chromosomes? https://bioinformaticsonline.com/bookmarks/view/39281/humcfs-a-database-of-fragile-sites-in-human-chromosomes Sun, 21 Apr 2019 20:17:29 -0500 https://bioinformaticsonline.com/bookmarks/view/39281/humcfs-a-database-of-fragile-sites-in-human-chromosomes <![CDATA[HumCFS: a database of fragile sites in human chromosomes]]> Fragile sites are specific chromosomal region that exhibit an increased frequency of chromosdomal breakge when cells are exposed to replicative stress. Since from the discovery of chromosomal fragile sites/regions (CFS), several line of evidence suggests their involvement in human pathologies and they have been recognized as a preferential site for integration of exogenous oncogenic DNA viruses and hotspots for chromosomal re-arrangement. There is large gap in our knowledge of human CFS region as knowledge about CFS are unequally distributed in literature, which impose a problem in studying these region. In order to address these issues, we develop this platform HumCFS, which provides comprehensive information about experimentally identified CFS at a single source.

https://link.springer.com/epdf/10.1186/s12864-018-5330-5?author_access_token=ICASEpyMAQaxLlKw--fyCG_BpE1tBhCbnbw3BuzI2RMA57KLmXk5bZabRUiDQzRFHXd6hjm4kWSiLV3mU5XVMitqXUwFMSo4x5vbfty0EDQ9PW1sd1h923_TYXkvJ5niSwAyZ7BklJ0ujFAFhcKtjw%3D%3D

Address of the bookmark: https://webs.iiitd.edu.in/raghava/humcfs/

]]> Abhimanyu Singh