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	<title><![CDATA[BOL: mosdepth: fast BAM/CRAM depth calculation for WGS, exome, or targeted sequencing]]></title>
	<link>https://bioinformaticsonline.com/bookmarks/view/40251/mosdepth-fast-bamcram-depth-calculation-for-wgs-exome-or-targeted-sequencing?</link>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/40251/mosdepth-fast-bamcram-depth-calculation-for-wgs-exome-or-targeted-sequencing</guid>
	<pubDate>Wed, 13 Nov 2019 22:20:19 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/40251/mosdepth-fast-bamcram-depth-calculation-for-wgs-exome-or-targeted-sequencing</link>
	<title><![CDATA[mosdepth: fast BAM/CRAM depth calculation for WGS, exome, or targeted sequencing]]></title>
	<description><![CDATA[<p>mosdepth can output:</p>
<p>per-base depth about 2x as fast samtools depth--about 25 minutes of CPU time for a 30X genome.<br>mean per-window depth given a window size--as would be used for CNV calling.<br>the mean per-region given a BED file of regions.<br>a distribution of proportion of bases covered at or above a given threshold for each chromosome and genome-wide.<br>quantized output that merges adjacent bases as long as they fall in the same coverage bins e.g. (10-20)<br>threshold output to indicate how many bases in each region are covered at the given thresholds.<br>A summary of mean depths per chromosome and within specified regions per chromosome.</p><p>Address of the bookmark: <a href="https://github.com/brentp/mosdepth" rel="nofollow">https://github.com/brentp/mosdepth</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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