<![CDATA[BOL: QuartataWeb: user-friendly server developed for polypharmacological and chemogenomics analyses.]]> https://bioinformaticsonline.com/bookmarks/view/41504/quartataweb-user-friendly-server-developed-for-polypharmacological-and-chemogenomics-analyses? https://bioinformaticsonline.com/bookmarks/view/41504/quartataweb-user-friendly-server-developed-for-polypharmacological-and-chemogenomics-analyses Wed, 01 Apr 2020 10:30:52 -0500 https://bioinformaticsonline.com/bookmarks/view/41504/quartataweb-user-friendly-server-developed-for-polypharmacological-and-chemogenomics-analyses <![CDATA[QuartataWeb: user-friendly server developed for polypharmacological and chemogenomics analyses.]]> Data on protein-drug and protein-chemical interactions are rapidly accumulating in databases such as DrugBank and STITCH. These data usually reflect observed interactions, while the lack of data for a given protein-drug/chemical pair does not necessarily mean the lack of interaction. Indeed, recent studies, both computational and experimental, highlighted the promiscuity of both proteins and small molecules: many drugs have side effects i.e. they target proteins other than those known in public databases; and many proteins bind chemicals other than those known, opening the way to design repurposable drugs, new chemicals, or polypharmacological treatments.

https://academic.oup.com/bioinformatics/advance-article/doi/10.1093/bioinformatics/btaa210/5813333

Address of the bookmark: http://quartata.csb.pitt.edu/

]]> Neel