<![CDATA[BOL: SVEngine: Allele Specific and Haplotype Aware Structural Variants Simulator]]> https://bioinformaticsonline.com/bookmarks/view/41941/svengine-allele-specific-and-haplotype-aware-structural-variants-simulator? https://bioinformaticsonline.com/bookmarks/view/41941/svengine-allele-specific-and-haplotype-aware-structural-variants-simulator Sat, 04 Jul 2020 05:52:34 -0500 https://bioinformaticsonline.com/bookmarks/view/41941/svengine-allele-specific-and-haplotype-aware-structural-variants-simulator <![CDATA[SVEngine: Allele Specific and Haplotype Aware Structural Variants Simulator]]> SVEngine (Structural Variants Engine)

  • SVEngine is a multi-purpose and self-contained simulator for whole genome scale spike-in of thousands of SV events of various types in both single-sample and matched sample scenarios.
  • SVEngine takes as input reference contigs in FASTA files, variant meta distribution as specified in META files (see Manual) or specific variant information as specified in VAR files (see Manual) and NEWICK files for specifying clonal phylogenetic trees in cancer.
  • SVEngine outpus alterred contigs in FASTA files, spiked-in variants in VAR files (see Manual), simulated short read in FASTQ files and aligned short reads in BAM files.

 

Address of the bookmark: https://bitbucket.org/charade/svengine/src/master/

]]> Jit https://bioinformaticsonline.com/bookmarks/view/41941/svengine-allele-specific-and-haplotype-aware-structural-variants-simulator#item-annotation-3861 Sat, 04 Jul 2020 06:01:14 -0500 https://bioinformaticsonline.com/bookmarks/view/41941/svengine-allele-specific-and-haplotype-aware-structural-variants-simulator#item-annotation-3861 <![CDATA[Comment by Jit]]> Another nice simulation tool

https://bioinformaticsonline.com/bookmarks/view/40302/simug-a-general-purpose-genome-simulator

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