<![CDATA[BOL: HapSolo: An optimization approach for removing secondary haplotigs during diploid genome assembly and scaffolding.]]> https://bioinformaticsonline.com/bookmarks/view/42267/hapsolo-an-optimization-approach-for-removing-secondary-haplotigs-during-diploid-genome-assembly-and-scaffolding? https://bioinformaticsonline.com/bookmarks/view/42267/hapsolo-an-optimization-approach-for-removing-secondary-haplotigs-during-diploid-genome-assembly-and-scaffolding Mon, 26 Oct 2020 21:23:36 -0500 https://bioinformaticsonline.com/bookmarks/view/42267/hapsolo-an-optimization-approach-for-removing-secondary-haplotigs-during-diploid-genome-assembly-and-scaffolding <![CDATA[HapSolo: An optimization approach for removing secondary haplotigs during diploid genome assembly and scaffolding.]]> Despite marked recent improvements in long-read sequencing technology, the assembly of diploid genomes remains a difficult task. A major obstacle is distinguishing between alternative contigs that represent highly heterozygous regions. If primary and secondary contigs are not properly identified, the primary assembly will overrepresent both the size and complexity of the genome, which complicates downstream analysis such as scaffolding.

More at https://github.com/esolares/HapSolo

Address of the bookmark: https://github.com/esolares/HapSolo

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