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	<title><![CDATA[BOL: Human Complete Genome]]></title>
	<link>https://bioinformaticsonline.com/bookmarks/view/43909/human-complete-genome?</link>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/43909/human-complete-genome</guid>
	<pubDate>Wed, 06 Jul 2022 06:42:55 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/43909/human-complete-genome</link>
	<title><![CDATA[Human Complete Genome]]></title>
	<description><![CDATA[<h1 dir="auto">Telomere-to-telomere consortium</h1>
<p dir="auto">We have sequenced the CHM13hTERT human cell line with a number of technologies. Human genomic DNA was extracted from the cultured cell line. As the DNA is native, modified bases will be preserved. The data includes 30x&nbsp;<a href="https://www.pacb.com/">PacBio</a>&nbsp;<a href="https://www.ncbi.nlm.nih.gov/sra/?term=SRX789768*+CHM13">HiFi</a>, 120x coverage of&nbsp;<a href="https://nanoporetech.com/">Oxford Nanopore</a>, 70x&nbsp;<a href="https://www.pacb.com/">PacBio</a>&nbsp;CLR, 50x&nbsp;<a href="https://www.10xgenomics.com/">10X Genomics</a>, as well as&nbsp;<a href="https://bionanogenomics.com/technology/dls-technology/">BioNano DLS</a>&nbsp;and&nbsp;<a href="https://arimagenomics.com/kit/">Arima Genomics HiC</a>. Most raw data is available from this site, with the exception of the PacBio data which was generated by the University of Washington/PacBio and is available from&nbsp;<a href="https://www.ncbi.nlm.nih.gov/sra?linkname=bioproject_sra_all&amp;from_uid=269593">NCBI SRA</a>.</p>
<p dir="auto">A UCSC browser is available for&nbsp;<a href="https://genome.ucsc.edu/h/GCA_009914755.4">v2.0</a>&nbsp;(as well as legacy&nbsp;<a href="http://genome.ucsc.edu/cgi-bin/hgTracks?genome=t2t-chm13-v1.0&amp;hubUrl=http://t2t.gi.ucsc.edu/chm13/hub/hub.txt">v1.0</a>&nbsp;and&nbsp;<a href="http://genome.ucsc.edu/cgi-bin/hgTracks?genome=t2t-chm13-v1.1&amp;hubUrl=http://t2t.gi.ucsc.edu/chm13/hub/hub.txt">v1.1</a>&nbsp;versions). An interactive dotplot visualization of all genomic repeats is also available from&nbsp;<a href="https://resgen.io/paper-data/T2T-Nurk-et-al-2021/views/t2t-identity-v2">resgen.io</a>. Known issues identified in the assembly are tracked at&nbsp;<a href="https://github.com/marbl/CHM13-issues">CHM13 issues</a>.</p>
<p dir="auto">&nbsp;</p>
<p dir="auto">MORE at&nbsp;https://github.com/marbl/CHM13</p><p>Address of the bookmark: <a href="https://www.science.org/doi/10.1126/science.abj6987" rel="nofollow">https://www.science.org/doi/10.1126/science.abj6987</a></p>]]></description>
	<dc:creator>Shruti Paniwala</dc:creator>
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