<![CDATA[BOL: Severus: a somatic structural variation (SV) caller for long reads]]> https://bioinformaticsonline.com/bookmarks/view/44499/severus-a-somatic-structural-variation-sv-caller-for-long-reads? https://bioinformaticsonline.com/bookmarks/view/44499/severus-a-somatic-structural-variation-sv-caller-for-long-reads Sun, 31 Mar 2024 02:41:27 -0500 https://bioinformaticsonline.com/bookmarks/view/44499/severus-a-somatic-structural-variation-sv-caller-for-long-reads <![CDATA[Severus: a somatic structural variation (SV) caller for long reads]]> Severus is a somatic structural variation (SV) caller for long reads (both PacBio and ONT). It is designed for matching tumor/normal analysis, supports multiple tumor samples, and produces accurate and complete somatic and germline calls. Severus takes advantage of long-read phasing and uses the breakpoint graph framework to model complex chromosomal rearrangements.

If you use Severus, please cite https://www.medrxiv.org/content/10.1101/2024.03.22.24304756v1

Address of the bookmark: https://github.com/KolmogorovLab/Severus

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