Check out the changes they made.

They added the cleanup-blastdb-volumes.py script to remove unused BLAST database volumes. Read the documentation here.

They also switched the protocol from ftp to https to access BLAST databases for increased performance and reliability when downloading data from the NCBI with the update_blastdb.pl script.

And fixed a few bugs related to downloading data from the NCBI, and mt_mode crashing blastn and blastx.

Check out the release notes.

Download BLAST+ 2.14.1

Questions or comments? Please write the BLAST help desk.

More info and download: https://blast.ncbi.nlm.nih.gov/doc/blast-news/2023-BLAST-News.html

GenBank release 257.0 (8/15/2023) is now available on the NCBI FTP site. This release has 25.10 trillion bases and 3.69 billion records.

The current release has:

• 246,119,175 traditional records containing 2,112,058,517,945 base pairs of sequence data
• 2,631,493,489 WGS records containing 22,294,446,104,543 base pairs of sequence data
• 686,271,945 bulk-oriented TSA records containing 646,176,166,908 base pairs of sequence data
• 124,421,006 bulk-oriented TLS records containing 48,289,699,026 base pairs of sequence data