<![CDATA[BOL: BioJoker's News]]> https://bioinformaticsonline.com/news/owner/biojoker? https://bioinformaticsonline.com/news/view/40596/igblast-a-popular-ncbi-package-for-classifying-and-analyzing-immunoglobulin-ig-and-t-cell-receptor-tcr-variable-domain-sequences Thu, 23 Jan 2020 11:34:37 -0600 https://bioinformaticsonline.com/news/view/40596/igblast-a-popular-ncbi-package-for-classifying-and-analyzing-immunoglobulin-ig-and-t-cell-receptor-tcr-variable-domain-sequences <![CDATA[IgBLAST: a popular NCBI package for classifying and analyzing immunoglobulin (IG) and T cell receptor (TCR) variable domain sequences]]> NCBI team released a new version of IgBLAST with four new improvements. IgBLAST is a popular NCBI package for classifying and analyzing immunoglobulin (IG) and T cell receptor (TCR) variable domain sequences. Improvements are:

    1. Support for the new FWR4 annotation feature in the AIRR format, both in standard format and in the AIRR alignment format.

    2. The previous “-penalty” parameter was renamed as -V_penalty to be consistent with other IgBLAST penalty options.

    3. Restored constant internal BLAST search parameters for domain annotation (i.e., FWR/CDR) such that this process is not influenced by user parameters.

    4. Corrected FWR/CDR annotations for certain mouse VK and rat VH germline genes. 

IgBLAST 1.15.0 is available for download from the BLAST FTP area. See the the new manual on GitHub for information about setting up and running IgBLAST.

 If you have any questions or concerns, please contact blast-help@ncbi.nlm.nih.gov

 

]]> BioJoker https://bioinformaticsonline.com/news/view/39378/your-turn-this-year Fri, 17 May 2019 03:16:45 -0500 https://bioinformaticsonline.com/news/view/39378/your-turn-this-year <![CDATA[YOUR TURN THIS YEAR?]]> Apply for the Science & SciLifeLab Prize for Young Scientists — an annual prize awarded to early-career scientists. The prize is presented in four categories: Cell and Molecular Biology, Ecology and Environment, Molecular Medicine, and Genomics, Proteomics and Systems Biology.

The winners will have their essays published by Science, win up to USD 30,000 and be invited to Sweden to attend the award ceremony. Get ready for a life-changing moment in your scientific career. 

Application deadline: July 15th, 2019

Eligible entrants must have been awarded their doctoral degree in 2017 or 2018. The winners from each category will compete for the Grand Prize. 

Read more: scienceprize.scilifelab.se
Questions/Inquiries: SciLifeLabPrize@aaas.org

“It has absolutely brought a lot of exposure to me and to my research. I also think it went a long way in helping me to get my current position.”

Allison Cleary, 2015 Grand Prize Winner

“My advice for those thinking about applying for the Science and SciLifeLab Prize is to just go for it! It wasn’t the easiest thing trying to frame my work in a broader context, but in the end, I think it was a very healthy experience. I think everyone could benefit from trying to do that with their work.“

Tim Wang, 2018 Category Winner

“I think it’s really remarkable to have a prize for young researchers because most of the prizes reward people that are established in their fields. And for us, it means a great deal, because we are only launching our careers now, and such a prize is probably going to a be an extreme help.”

Mijo Simunovic, 2017 Category Winner

 

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