<![CDATA[BOL: A-allele of SLC24A5 gene is found to be responsible for variation in skin color of South-East Asians and Europeans]]> https://bioinformaticsonline.com/news/view/6302/a-allele-of-slc24a5-gene-is-found-to-be-responsible-for-variation-in-skin-color-of-south-east-asians-and-europeans? https://bioinformaticsonline.com/news/view/6302/a-allele-of-slc24a5-gene-is-found-to-be-responsible-for-variation-in-skin-color-of-south-east-asians-and-europeans Tue, 12 Nov 2013 21:02:27 -0600 https://bioinformaticsonline.com/news/view/6302/a-allele-of-slc24a5-gene-is-found-to-be-responsible-for-variation-in-skin-color-of-south-east-asians-and-europeans <![CDATA[A-allele of SLC24A5 gene is found to be responsible for variation in skin color of South-East Asians and Europeans]]> Key finding:

  1. rs1426654 SNP of SLC24A5 gene is decider of skin pigmentation variation in South Asia
  2. rs1426654-A allele is widely spread throughout the Indian subcontinent 
  3. Skin pigmentation is also account by the combination of processes like selection and demographic history of populations affected by their language and origin
  4. Sign of positive selection in Europeans, Middle East, Pakistan, Central Asia and North India but not in South India
  5. In European , A-allele is almost reached to fixation

Paper:

http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1003912

]]> Rahul Agarwal