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<channel>
	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/10925?offset=1200</link>
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	<description><![CDATA[]]></description>
	
	<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/43431/code-golf</guid>
	<pubDate>Wed, 06 Oct 2021 04:17:29 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/43431/code-golf</link>
	<title><![CDATA[Code Golf]]></title>
	<description><![CDATA[<p>Code Golf is a game designed to let you show off your code-fu by solving problems in the least number of characters.</p>
<p>Since this is your first time here, I suggest starting with something simple like&nbsp;<a href="https://code.golf/fizz-buzz">Fizz Buzz</a>.</p><p>Address of the bookmark: <a href="https://code.golf/" rel="nofollow">https://code.golf/</a></p>]]></description>
	<dc:creator>Abhi</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/44633/learn-python-with-example</guid>
	<pubDate>Tue, 06 Aug 2024 23:51:51 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/44633/learn-python-with-example</link>
	<title><![CDATA[Learn python with example]]></title>
	<description><![CDATA[<div><div><div><p>There are over 21 unique&nbsp;Python project&nbsp;walkthroughs in this content that range from beginner to advanced. See below for the timestamps for these projects:</p><p><span>00:00:00 | How To Navigate These Projects</span><br /><span>---</span><br /><span>00:01:46 | #1 - Quiz Game (Easy)</span><br /><span>Code:&nbsp;</span><a href="https://morioh.com/redirect?id=65b0752318cf2dc4d28010e1&amp;own=5ff684ea1a53c42123416f96&amp;l=https%3A%2F%2Fgithub.com%2Ftechwithtim%2F5-Python-Projects-For-Beginners%2Fblob%2Fmain%2Fquiz_game.py" target="_blank">https://github.com/techwithtim/5-Python-Projects-For-Beginners/blob/main/quiz_game.py</a><span>&nbsp;</span><br /><span>---</span><br /><span>00:22:00 | #2 - Number Guessing Game (Easy)</span><br /><span>Code:&nbsp;</span><a href="https://morioh.com/redirect?id=65b0752318cf2dc4d28010e1&amp;own=5ff684ea1a53c42123416f96&amp;l=https%3A%2F%2Fgithub.com%2Ftechwithtim%2F5-Python-Projects-For-Beginners%2Fblob%2Fmain%2Fnumber_guesser.py" target="_blank">https://github.com/techwithtim/5-Python-Projects-For-Beginners/blob/main/number_guesser.py</a><span>&nbsp;</span><br /><span>---</span><br /><span>00:39:49 | #3 - Rock, Paper, Scissors (Easy)</span><br /><span>Code:&nbsp;</span><a href="https://morioh.com/redirect?id=65b0752318cf2dc4d28010e1&amp;own=5ff684ea1a53c42123416f96&amp;l=https%3A%2F%2Fgithub.com%2Ftechwithtim%2F5-Python-Projects-For-Beginners%2Fblob%2Fmain%2Frock_paper_scissors.py" target="_blank">https://github.com/techwithtim/5-Python-Projects-For-Beginners/blob/main/rock_paper_scissors.py</a><span>&nbsp;</span><br /><span>---</span><br /><span>00:54:40 | #4 - Choose Your Own Adventure Game (Easy)</span><br /><span>Code:&nbsp;</span><a href="https://morioh.com/redirect?id=65b0752318cf2dc4d28010e1&amp;own=5ff684ea1a53c42123416f96&amp;l=https%3A%2F%2Fgithub.com%2Ftechwithtim%2F5-Python-Projects-For-Beginners%2Fblob%2Fmain%2Fchoose_your_own_adventure.py" target="_blank">https://github.com/techwithtim/5-Python-Projects-For-Beginners/blob/main/choose_your_own_adventure.py</a><span>&nbsp;</span><br /><span>---</span><br /><span>01:06:47 | #5 - Password Manager (Medium)</span><br /><span>Code:&nbsp;</span><a href="https://morioh.com/redirect?id=65b0752318cf2dc4d28010e1&amp;own=5ff684ea1a53c42123416f96&amp;l=https%3A%2F%2Fgithub.com%2Ftechwithtim%2F5-Python-Projects-For-Beginners%2F" target="_blank">https://github.com/techwithtim/5-Python-Projects-For-Beginners/</a><span>&nbsp;</span><br /><span>Fernet Cryptography Documentation:&nbsp;</span><a href="https://morioh.com/redirect?id=65b0752318cf2dc4d28010e1&amp;own=5ff684ea1a53c42123416f96&amp;l=https%3A%2F%2Fcryptography.io%2Fen%2Flatest%2Ffernet%2F" target="_blank">https://cryptography.io/en/latest/fernet/</a><span>&nbsp;</span><br /><span>---</span><br /><span>01:37:37 | #6 - PIG (Medium)</span><br /><span>Code:&nbsp;</span><a href="https://morioh.com/redirect?id=65b0752318cf2dc4d28010e1&amp;own=5ff684ea1a53c42123416f96&amp;l=https%3A%2F%2Fgithub.com%2Ftechwithtim%2F3-Mini-Python-Projects%2Fblob%2Fmain%2Fproject1.py" target="_blank">https://github.com/techwithtim/3-Mini-Python-Projects/blob/main/project1.py</a><span>&nbsp;</span><br /><span>---</span><br /><span>01:59:07 | #7 - Madlibs Generator (Medium)</span><br /><span>Code:&nbsp;</span><a href="https://morioh.com/redirect?id=65b0752318cf2dc4d28010e1&amp;own=5ff684ea1a53c42123416f96&amp;l=https%3A%2F%2Fgithub.com%2Ftechwithtim%2F3-Mini-Python-Projects%2Fblob%2Fmain%2Fproject2.py" target="_blank">https://github.com/techwithtim/3-Mini-Python-Projects/blob/main/project2.py</a><span>&nbsp;</span><br /><span>---</span><br /><span>02:15:04 | #8 - Timed Math Challenge (Medium)</span><br /><span>Code:&nbsp;</span><a href="https://morioh.com/redirect?id=65b0752318cf2dc4d28010e1&amp;own=5ff684ea1a53c42123416f96&amp;l=https%3A%2F%2Fgithub.com%2Ftechwithtim%2F3-Mini-Python-Projects%2Fblob%2Fmain%2Fproject3.py" target="_blank">https://github.com/techwithtim/3-Mini-Python-Projects/blob/main/project3.py</a><span>&nbsp;</span><br /><span>---</span><br /><span>02:28:02 | #9 - Slot Machine (Medium)</span><br /><span>Code:&nbsp;</span><a href="https://morioh.com/redirect?id=65b0752318cf2dc4d28010e1&amp;own=5ff684ea1a53c42123416f96&amp;l=https%3A%2F%2Fgithub.com%2Ftechwithtim%2FPython-Slot-Machine" target="_blank">https://github.com/techwithtim/Python-Slot-Machine</a><span>&nbsp;</span><br /><span>---</span><br /><span>03:20:43 | #10 - Turtle Racing (Medium)</span><br /><span>Code:&nbsp;</span><a href="https://morioh.com/redirect?id=65b0752318cf2dc4d28010e1&amp;own=5ff684ea1a53c42123416f96&amp;l=https%3A%2F%2Fgithub.com%2Ftechwithtim%2FTurtle-Racing-V2" target="_blank">https://github.com/techwithtim/Turtle-Racing-V2</a><span>&nbsp;</span><br /><span>Turtle Docs:&nbsp;</span><a href="https://morioh.com/redirect?id=65b0752318cf2dc4d28010e1&amp;own=5ff684ea1a53c42123416f96&amp;l=https%3A%2F%2Fdocs.python.org%2F3%2Flibrary%2Fturtle.html" target="_blank">https://docs.python.org/3/library/turtle.html</a><span>&nbsp;</span><br /><span>---</span><br /><span>04:13:09 | #11 - WPM Typing Test (Medium)</span><br /><span>Code:&nbsp;</span><a href="https://morioh.com/redirect?id=65b0752318cf2dc4d28010e1&amp;own=5ff684ea1a53c42123416f96&amp;l=https%3A%2F%2Fgithub.com%2Ftechwithtim%2FWPM_Typing_Test" target="_blank">https://github.com/techwithtim/WPM_Typing_Test</a><span>&nbsp;</span><br /><span>Curses Docs:&nbsp;</span><a href="https://morioh.com/redirect?id=65b0752318cf2dc4d28010e1&amp;own=5ff684ea1a53c42123416f96&amp;l=https%3A%2F%2Fdocs.python.org%2F3%2Fhowto%2Fcurses.html" target="_blank">https://docs.python.org/3/howto/curses.html</a><span>&nbsp;</span><br /><span>05:09:43 | #12 - Alarm Clock (Easy)</span><br /><span>Python Project Idea Blog:&nbsp;</span><a href="https://morioh.com/redirect?id=65b0752318cf2dc4d28010e1&amp;own=5ff684ea1a53c42123416f96&amp;l=https%3A%2F%2Fhackr.io%2Fblog%2Fpython-projects" target="_blank">https://hackr.io/blog/python-projects</a><span>&nbsp;</span><br /><span>Sound Effects:&nbsp;</span><a href="https://morioh.com/redirect?id=65b0752318cf2dc4d28010e1&amp;own=5ff684ea1a53c42123416f96&amp;l=https%3A%2F%2Fwww.fesliyanstudios.com%2Froyalty-free-sound-effects-download%2Falarm-203" target="_blank">https://www.fesliyanstudios.com/royalty-free-sound-effects-download/alarm-203</a><span>&nbsp;</span><br /><span>---</span><br /><span>05:22:07 | #13 - Password Generator (Easy)</span><br /><span>Python Project Idea Blog:&nbsp;</span><a href="https://morioh.com/redirect?id=65b0752318cf2dc4d28010e1&amp;own=5ff684ea1a53c42123416f96&amp;l=https%3A%2F%2Fhackr.io%2Fblog%2Fpython-projects" target="_blank">https://hackr.io/blog/python-projects</a><span>&nbsp;</span><br /><span>---</span><br /><span>05:39:16 | #14 - Shortest Path Finder (Advanced)</span><br /><span>Code:&nbsp;</span><a href="https://morioh.com/redirect?id=65b0752318cf2dc4d28010e1&amp;own=5ff684ea1a53c42123416f96&amp;l=https%3A%2F%2Fgithub.com%2Ftechwithtim%2F3-Mini-Python-Projects-For-Intermediates%2Fblob%2Fmain%2Fpath-finder.py" target="_blank">https://github.com/techwithtim/3-Mini-Python-Projects-For-Intermediates/blob/main/path-finder.py</a><span>&nbsp;</span><br /><span>---</span><br /><span>06:14:53 | #15 - NBA Stats &amp; Current Scores (Medium)</span><br /><span>Code:&nbsp;</span><a href="https://morioh.com/redirect?id=65b0752318cf2dc4d28010e1&amp;own=5ff684ea1a53c42123416f96&amp;l=https%3A%2F%2Fgithub.com%2Ftechwithtim%2F3-Mini-Python-Projects-For-Intermediates%2Fblob%2Fmain%2Fnba-scores.py" target="_blank">https://github.com/techwithtim/3-Mini-Python-Projects-For-Intermediates/blob/main/nba-scores.py</a><span>&nbsp;</span><br /><span>---</span><br /><span>06:38:22 | #16 - Currency Converter (Medium)</span><br /><span>Code:&nbsp;</span><a href="https://morioh.com/redirect?id=65b0752318cf2dc4d28010e1&amp;own=5ff684ea1a53c42123416f96&amp;l=https%3A%2F%2Fgithub.com%2Ftechwithtim%2F3-Mini-Python-Projects-For-Intermediates%2Fblob%2Fmain%2Fcurrency-converter.py" target="_blank">https://github.com/techwithtim/3-Mini-Python-Projects-For-Intermediates/blob/main/currency-converter.py</a><span>&nbsp;</span><br /><span>API: https://free.currencyconverterapi.com/</span><br /><span>---</span><br /><span>06:58:51 | #17 - YouTube Video Downloader (Medium)</span><br /><span>Code: &nbsp;</span><a href="https://morioh.com/redirect?id=65b0752318cf2dc4d28010e1&amp;own=5ff684ea1a53c42123416f96&amp;l=https%3A%2F%2Fgithub.com%2Ftechwithtim%2FPython-Beginner-Automation-Projects%2Fblob%2Fmain%2Fyoutube.py" target="_blank">https://github.com/techwithtim/Python-Beginner-Automation-Projects/blob/main/youtube.py</a><span>&nbsp;</span><br /><span>---</span><br /><span>07:09:50 | #18 - Automated File Backup (Medium)</span><br /><span>Code:&nbsp;</span><a href="https://morioh.com/redirect?id=65b0752318cf2dc4d28010e1&amp;own=5ff684ea1a53c42123416f96&amp;l=https%3A%2F%2Fgithub.com%2Ftechwithtim%2FPython-Beginner-Automation-Projects%2Fblob%2Fmain%2Fbackup.py" target="_blank">https://github.com/techwithtim/Python-Beginner-Automation-Projects/blob/main/backup.py</a><span>&nbsp;</span><br /><span>---</span><br /><span>07:21:18 | #19 - Mastermind/4 Color Match (Advanced)</span><br /><span>---</span><br /><span>07:48:20 | #20 - Aim Trainer (Advanced)</span><br /><span>Code:&nbsp;</span><a href="https://morioh.com/redirect?id=65b0752318cf2dc4d28010e1&amp;own=5ff684ea1a53c42123416f96&amp;l=https%3A%2F%2Fgithub.com%2Ftechwithtim%2FPython-Aim-Trainer" target="_blank">https://github.com/techwithtim/Python-Aim-Trainer</a><span>&nbsp;</span><br /><span>---</span><br /><span>08:39:20 | #21 - Advanced Python Scripting (Advanced)</span><br /><span>Code:&nbsp;</span><a href="https://morioh.com/redirect?id=65b0752318cf2dc4d28010e1&amp;own=5ff684ea1a53c42123416f96&amp;l=https%3A%2F%2Fgithub.com%2Ftechwithtim%2FPython-Scripting-Project" target="_blank">https://github.com/techwithtim/Python-Scripting-Project</a><span>&nbsp;</span></p></div></div></div>]]></description>
	<dc:creator>BioStar</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/44648/modern-statistics-with-r</guid>
	<pubDate>Thu, 22 Aug 2024 04:44:06 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/44648/modern-statistics-with-r</link>
	<title><![CDATA[Modern Statistics with R]]></title>
	<description><![CDATA[<p>This is the online version of the second edition of&nbsp;<em>Modern Statistics with R</em>. It is free to use, and always will be.&nbsp;<a href="https://www.routledge.com/Modern-Statistics-with-R-From-Wrangling-and-Exploring-Data-to-Inference-and-Predictive-Modelling/Thulin/p/book/9781032512440">Printed copies</a>&nbsp;are available from CRC Press.</p>
<p><span>Live&nbsp;<a href="https://statistikakademin.se/in-english-r/">online courses on statistics with R</a></span>&nbsp;based on this book, led by the author, are offered regularly; see&nbsp;<a href="https://statistikakademin.se/in-english-r/">this page</a>&nbsp;for more information and dates.</p>
<p>The past decades have transformed the world of statistical data analysis, with new methods, new types of data, and new computational tools. The aim of&nbsp;<em>Modern Statistics with R</em>&nbsp;is to introduce you to key parts of the modern statistical toolkit. It teaches you:</p>
<ul>
<li><span>Data wrangling</span>&nbsp;- importing, formatting, reshaping, merging, and filtering data in R.</li>
<li><span>Exploratory data analysis</span>&nbsp;- using visualisations and multivariate techniques to explore datasets.</li>
<li><span>Statistical inference</span>&nbsp;- modern methods for testing hypotheses and computing confidence intervals.</li>
<li><span>Predictive modelling</span>&nbsp;- regression models and machine learning methods for prediction, classification, and forecasting.</li>
<li><span>Simulation</span>&nbsp;- using simulation techniques for sample size computations and evaluations of statistical methods.</li>
<li><span>Ethics in statistics</span>&nbsp;- ethical issues and good statistical practice.</li>
<li><span>R programming</span>&nbsp;- writing code that is fast, readable, and (hopefully!) free from bugs.</li>
</ul>
<p>The book includes plenty of examples and more than 200 exercises with worked solutions.&nbsp;<a href="http://www.modernstatisticswithr.com/data.zip">The datasets used for the examples and the exercises can be downloaded here.</a></p><p>Address of the bookmark: <a href="https://www.modernstatisticswithr.com/" rel="nofollow">https://www.modernstatisticswithr.com/</a></p>]]></description>
	<dc:creator>LEGE</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/38563/hecil-a-hybrid-error-correction-algorithm-for-long-reads-with-iterative-learning</guid>
	<pubDate>Tue, 01 Jan 2019 12:01:00 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/38563/hecil-a-hybrid-error-correction-algorithm-for-long-reads-with-iterative-learning</link>
	<title><![CDATA[HECIL: A Hybrid Error Correction Algorithm for Long Reads with Iterative Learning]]></title>
	<description><![CDATA[<p><span>HECIL&mdash;Hybrid Error Correction with Iterative Learning&mdash;a hybrid error correction framework that determines a correction policy for erroneous long reads, based on optimal combinations of decision weights obtained from short read alignments.&nbsp;</span></p>
<p><span><span>HECIL&rsquo;s core algorithm by introducing an iterative learning paradigm that enhances the correction policy at each iteration by incorporating knowledge gathered from previous iterations via data-driven confidence metrics assigned to prior corrections.</span></span></p><p>Address of the bookmark: <a href="https://github.com/NDBL/HECIL" rel="nofollow">https://github.com/NDBL/HECIL</a></p>]]></description>
	<dc:creator>Abhimanyu Singh</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/36849/glean-an-unsupervised-learning-system-to-integrate-disparate-sources-of-gene-structure-evidence</guid>
	<pubDate>Sat, 02 Jun 2018 07:38:33 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/36849/glean-an-unsupervised-learning-system-to-integrate-disparate-sources-of-gene-structure-evidence</link>
	<title><![CDATA[GLEAN: an unsupervised learning system to integrate disparate sources of gene structure evidence]]></title>
	<description><![CDATA[<p><span>GLEAN is an unsupervised learning system to integrate disparate sources of gene structure evidence (gene model predictions, EST/protein genomic sequence alignments, SAGE/peptide tags, etc) to produce a consensus gene prediction, without prior training.</span></p><p>Address of the bookmark: <a href="https://sourceforge.net/projects/glean-gene/" rel="nofollow">https://sourceforge.net/projects/glean-gene/</a></p>]]></description>
	<dc:creator>Poonam Mahapatra</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/43831/ten-quick-tips-for-deep-learning-in-biology</guid>
	<pubDate>Fri, 25 Mar 2022 18:35:12 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/43831/ten-quick-tips-for-deep-learning-in-biology</link>
	<title><![CDATA[Ten quick tips for deep learning in biology]]></title>
	<description><![CDATA[<p><span>By taking a comprehensive and careful approach to deep learning based on critical thinking about research questions, planning to maintain rigor, and discerning how work might have far-reaching consequences with ethical dimensions, the life science community can advance reproducible, interpretable, and high-quality science that is enriching and beneficial for both scientists and society.</span></p><p>Address of the bookmark: <a href="https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1009803" rel="nofollow">https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1009803</a></p>]]></description>
	<dc:creator>Neel</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/33976/goldgenomes-online-database</guid>
	<pubDate>Wed, 26 Jul 2017 07:49:29 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/33976/goldgenomes-online-database</link>
	<title><![CDATA[GOLD:Genomes Online Database]]></title>
	<description><![CDATA[<p><span>GOLD</span><span>:Genomes Online Database, is a World Wide Web resource for comprehensive access to information regarding genome and metagenome sequencing projects, and their associated metadata, around the world.</span></p>
<p>https://gold.jgi.doe.gov/</p><p>Address of the bookmark: <a href="https://gold.jgi.doe.gov/" rel="nofollow">https://gold.jgi.doe.gov/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/923/phylogenetic-for-bioinformatics</guid>
	<pubDate>Tue, 16 Jul 2013 03:50:30 -0500</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/923/phylogenetic-for-bioinformatics</link>
	<title><![CDATA[Phylogenetic for Bioinformatics]]></title>
	<description><![CDATA[<p>Biologists estimate that there are about 5 to 100 million species of organisms living on Earth today. Evidence from morphological, biochemical, and gene sequence data suggests that all organisms on Earth are genetically related, and the genealogical relationships of living things can be represented by a vast evolutionary tree, the Tree of Life. The Tree of Life then represents the phylogeny of organisms, i. e., the history of organismal lineages as they change through time.<br />Every living organism contains DNA, RNA, and proteins. Closely related organisms generally have a high degree of agreement in the molecular structure of these substances, while the molecules of organisms distantly related usually show a pattern of dissimilarity. Molecular phylogeny uses such data to build a "relationship tree" that shows the probable evolution of various organisms. Not until recent decades, however, has it been possible to isolate and identify these molecular structures.&nbsp;<br />phylogenetics is the study of evolutionary relatedness among various groups of organisms (for example, species or populations), which is discovered through molecular sequencing data and morphological data matrices. In other word, Phylogenetics, the science of phylogeny, is one part of the larger field of systematics, which also includes taxonomy. Taxonomy is the science of naming and classifying the diversity of organisms Molecular phylogeny is the use of the structure of molecules to gain information on an organism's evolutionary relationships. The result of a molecular phylogenetic analysis is expressed in a so-called phylogenetic tree.</p><p>The evolutionary connections between organisms are represented graphically through phylogenetic trees. Due to the fact that evolution takes place over long periods of time that cannot be observed directly, biologists must reconstruct phylogenies by inferring the evolutionary relationships among present-day organisms.&nbsp;<br />Application of the techniques that make this possible can be seen in the very limited field of human genetics, such as the ever more popular use of genetic testing to determine a child's paternity, as well as the emergence of a new branch of criminal forensics focused on genetic evidence.<br />The effect on traditional scientific classification schemes in the biological sciences has been dramatic as well. Work that was once immensely labor- and materials-intensive can now be done quickly and easily, leading to yet another source of information becoming available for systematic and taxonomic appraisal. This particular kind of data has become so popular that taxonomical schemes based solely on molecular data may be encountered. Proponents even claim that taxonomy was previously based on morphology alone, which of course is utter fable.<br /><br /><strong>For additional information on phylogenetics, see list of Phylogenetics Resources on the Internet.</strong></p><p>Phylogeny and Reconstructing Phylogenetic Trees:&nbsp;<a href="http://aleph0.clarku.edu/~djoyce/java/Phyltree/cover.html"></a><a href="http://aleph0.clarku.edu/~djoyce/java/Phyltree/cover.html">http://aleph0.clarku.edu/~djoyce/java/Phyltree/cover.html</a><br />the CBRG and Department of Statistics Phylogeny tutorial:&nbsp;<a href="http://www.compbio.ox.ac.uk/tutorials/phylogeny/"></a><a href="http://www.compbio.ox.ac.uk/tutorials/phylogeny/">http://www.compbio.ox.ac.uk/tutorials/phylogeny/</a><br />TUTORIAL: PHYLOGENETIC ANALYSIS USING PARSIMONY:<a href="http://home.cc.umanitoba.ca/~psgendb/GDE/phylogeny/parsimony/phylip.parsimony.html"></a><a href="http://home.cc.umanitoba.ca/~psgendb/GDE/phylogeny/parsimony/phylip.parsimony.html">http://home.cc.umanitoba.ca/~psgendb/GDE/phylogeny/parsimony/phylip.parsimony.html</a></p><p>PHYLIP:&nbsp;<a href="http://www.umanitoba.ca/afs/plant_science/psgendb/doc/Phylip/main.html"></a><a href="http://www.umanitoba.ca/afs/plant_science/psgendb/doc/Phylip/main.html">http://www.umanitoba.ca/afs/plant_science/psgendb/doc/Phylip/main.html</a><br />An Introduction to Molecular Phylogeny:&nbsp;<a href="http://bibiserv.techfak.uni-bielefeld.de/gcb04/tutorials/hoef-emden/GCB04Tut.pdf"></a><a href="http://bibiserv.techfak.uni-bielefeld.de/gcb04/tutorials/hoef-emden/GCB04Tut.pdf">http://bibiserv.techfak.uni-bielefeld.de/gcb04/tutorials/hoef-emden/GCB04Tut.pdf</a></p><p>How to make a phylogenetic tree:&nbsp;<a href="http://www.hiv.lanl.gov/content/sequence/TUTORIALS/TREE_TUTORIAL/Tree"></a><a href="http://www.hiv.lanl.gov/content/sequence/TUTORIALS/TREE_TUTORIAL/Tree">http://www.hiv.lanl.gov/content/sequence/TUTORIALS/TREE_TUTORIAL/Tree</a>tutorial.html<br />Phylogenetic Trees:&nbsp;<a href="http://cnx.org/content/m11052/latest/"></a><a href="http://cnx.org/content/m11052/latest/">http://cnx.org/content/m11052/latest/</a><br />Phylogeny by Ron Shamir:&nbsp;<a href="http://www.cs.tau.ac.il/~rshamir/algmb/01/scribe08/lec08.pdf"></a><a href="http://www.cs.tau.ac.il/~rshamir/algmb/01/scribe08/lec08.pdf">http://www.cs.tau.ac.il/~rshamir/algmb/01/scribe08/lec08.pdf</a><br />Introduction to Phylogeny:&nbsp;<a href="http://www.utm.edu/departments/cens/biology/rirwin/391/391Phylog.htm"></a><a href="http://www.utm.edu/departments/cens/biology/rirwin/391/391Phylog.htm">http://www.utm.edu/departments/cens/biology/rirwin/391/391Phylog.htm</a><br />Lecturer notes on Phylogeny:&nbsp;<a href="http://www.sbc.su.se/~bens/course_material/phylocourse1/lecture2.pdf"></a><a href="http://www.sbc.su.se/~bens/course_material/phylocourse1/lecture2.pdf">http://www.sbc.su.se/~bens/course_material/phylocourse1/lecture2.pdf</a><br />Principles and Practice of Phylogenetic Systematics:<a href="http://www.faculty.biol.ttu.edu/Strauss/Phylogenetics/LectureNotes.htm"></a><a href="http://www.faculty.biol.ttu.edu/Strauss/Phylogenetics/LectureNotes.htm">http://www.faculty.biol.ttu.edu/Strauss/Phylogenetics/LectureNotes.htm</a></p><p>Inferring phylogenetic trees:&nbsp;<a href="http://www.cis.hut.fi/Opinnot/T-61.6070/slides2008/pres_6070.pdf"></a><a href="http://www.cis.hut.fi/Opinnot/T-61.6070/slides2008/pres_6070.pdf">http://www.cis.hut.fi/Opinnot/T-61.6070/slides2008/pres_6070.pdf</a></p><p><strong>Lecture Notes</strong></p><p>Chapter 1 - The Diversity, Classification, and Evolution of Vertebrates:<a href="http://academic.emporia.edu/mooredwi/nathist/chap1.htm"></a><a href="http://academic.emporia.edu/mooredwi/nathist/chap1.htm">http://academic.emporia.edu/mooredwi/nathist/chap1.htm</a></p><p>Algorithms for Phylogenetic Reconstructions:<a href="http://lectures.molgen.mpg.de/Algorithmische_Bioinformatik_WS0405/phylogeny_script.pdf"></a><a href="http://lectures.molgen.mpg.de/Algorithmische_Bioinformatik_WS0405/phylogeny_script.pdf">http://lectures.molgen.mpg.de/Algorithmische_Bioinformatik_WS0405/phylogeny_script.pdf</a></p><p>Phylogeny.fr is a free, simple to use web service dedicated to reconstructing and analysing phylogenetic relationships between molecular sequences. Phylogeny.fr runs and connects various bioinformatics programs to reconstruct a robust phylogenetic tree from a set of sequences. For more detail :&nbsp;<a href="http://www.phylogeny.fr/version2_cgi/index.cgi"></a><a href="http://www.phylogeny.fr/version2_cgi/index.cgi">http://www.phylogeny.fr/version2_cgi/index.cgi</a></p><p>A Brief Tutorial on Phylogenetics<br /><a href="http://bioss.ac.uk/~dirk/talks/tutorial_phylogenetics.pdf"></a><a href="http://bioss.ac.uk/~dirk/talks/tutorial_phylogenetics.pdf">http://bioss.ac.uk/~dirk/talks/tutorial_phylogenetics.pdf</a></p><p>A Brief Tutorial on Phylogenetics Human Rabbit Chicken<br /><a href="http://bioss.ac.uk/~dirk/talks/psnup_tutorial_phylogenetics.pdf"></a><a href="http://bioss.ac.uk/~dirk/talks/psnup_tutorial_phylogenetics.pdf">http://bioss.ac.uk/~dirk/talks/psnup_tutorial_phylogenetics.pdf</a></p><p>Phylogenetic Tree Computation Tutorial Overview<br /><a href="http://pga.lbl.gov/Workshop/April2002/lectures/Olken.pdf"></a><a href="http://pga.lbl.gov/Workshop/April2002/lectures/Olken.pdf">http://pga.lbl.gov/Workshop/April2002/lectures/Olken.pdf</a></p><p>MrBayes: A program for the Bayesian inference of phylogeny<br /><a href="http://golab.unl.edu/teaching/SBseminar/manual.pdf"></a><a href="http://golab.unl.edu/teaching/SBseminar/manual.pdf">http://golab.unl.edu/teaching/SBseminar/manual.pdf</a></p><p><strong>Web sites providing software for the construction of phylogenetic trees</strong></p><ul>
<li><a href="http://www.mbio.ncsu.edu/BioEdit/bioedit.html">BioEdit</a></li>
</ul><ul>
<li><a href="http://www.dinofish.com/">Coelocanth-Fish Out of Time</a></li>
</ul><ul>
<li><a href="http://cbrg.inf.ethz.ch/">Computational Biochemistry Research Group</a></li>
</ul><ul>
<li><a href="http://www.geocities.com/RainForest/Vines/8695/software.html">Digital Taxonomy</a></li>
</ul><ul>
<li><a href="http://www.cladistics.org/education/hennig86.html">Hennig 86</a></li>
</ul><ul>
<li><a href="http://www.bioinformaticssolutions.com/">Hyperclean</a>&nbsp;from Bioinformatics Solutions, Inc.</li>
</ul><ul>
<li><a href="http://www.mun.ca/biology/scarr/Directory.html">Memorial University of Newfoundland</a></li>
</ul><ul>
<li><a href="http://morphbank.ebc.uu.se/mrbayes/">Mr. Bayes</a></li>
</ul><ul>
<li><a href="http://www.cladistics.com/about_nona.htm">NONA</a></li>
</ul><ul>
<li><a href="http://evolve.zoo.ox.ac.uk/">Oxford University Evolutionary Biology Group</a></li>
</ul><ul>
<li><a href="http://flatpebble.nceas.ucsb.edu/public/">Paleobiology Database</a></li>
</ul><ul>
<li><a href="http://paup.csit.fsu.edu/index.html">PAUP</a></li>
</ul><ul>
<li><a href="http://evolution.genetics.washington.edu/phylip.html">Phylip Homepage</a></li>
</ul><ul>
<li><a href="http://research.amnh.org/scicomp/projects/poy.php">Poy</a></li>
</ul><ul>
<li><a href="http://www.sinauer.com/">Sinauer Associates</a></li>
</ul><ul>
<li><a href="http://www.cladistics.org/downloads/webtnt.html">TNT</a>-Tree Analysis Using New Technology</li>
</ul><ul>
<li><a href="http://www.treebase.org/treebase/index.html">Tree Base</a></li>
</ul><ul>
<li><a href="http://www.treefinder.de/">Treefinder</a></li>
</ul><ul>
<li><a href="http://www.tree-puzzle.de/">Tree-Puzzle</a></li>
</ul><ul>
<li><a href="http://taxonomy.zoology.gla.ac.uk/rod/treeview.html">Tree View</a>-Taxonomy and Systematics Group at Glasgow</li>
</ul><ul>
<li><a href="http://evolution.genetics.washington.edu/phylip/software.html">Washington University</a>-List of Phylogeny Software</li>
</ul>]]></description>
	<dc:creator>Jitendra Narayan</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/12883/breaking-chromosomes-to-study-cancer</guid>
	<pubDate>Fri, 18 Jul 2014 05:42:09 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/12883/breaking-chromosomes-to-study-cancer</link>
	<title><![CDATA[Breaking chromosomes to study cancer !!!]]></title>
	<description><![CDATA[<p>Chromosomes are present in every cell of our body and they contain the information the body needs to develop and function properly. This information is carried in genes that are arranged along the chromosomes. There are usually 46 chromosomes in every cell. These chromosomes come in pairs, one from our mother and one from our father. The chromosomes can be sorted into 23 pairs by looking at them down a microscope.</p><p>Most people who have a balanced translocation have the right amount of chromosome material but it has been rearranged in some way. This may happen if two chromosomes swap pieces (a reciprocal translocation). In other cases two whole chromosomes may become stuck together (a Robertsonian translocation). This page describes what happens when someone has a reciprocal translocation. <br /><br />Reciprocal chromosomal translocations occur following double-strand breaks (DSBs) in DNA when a section of one chromosome is exchanged with that of another, non-homologous chromosome. These exchanges may produce a dysfunctional fusion gene that disrupts cell growth and survival pathways, such as the translocations seen in leukemia and childhood sarcomas. <br /><br />Chromosomal translocations have been well studied in cancer cell lines which are associated with two types of cancer, acute myeloid leukemia and Ewing's sarcoma, but determining how they contribute to cancer development is complicated by additional mutations and altered gene expression profiles in these cultured cells. Now, Juan Carlos Ramirez, head of the Viral Vector Facility at the Fundacion Centro Nacional de Investigaciones Cardiovasculares (CNIC) and his colleagues Raul Torres at CNIC and Sandra Rodriguez-Peralez at the Spanish National Cancer Center (CNIO) in Madrid, Spain have used a new genome editing tool, CRISPR-Cas9, to induce chromosomal translocations for the first time in a human cell line and in primary cells. The study's authors conclude by stating that the use of this technology will allow for the clarification of how and why chromosomal translocation occurs, which without doubt will allow new anti-cancer therapeutic strategies to be tackled.</p><p>Using RNA-Guided Endonuclease (RGEN) technology or CRISPR/Cas9 genome engineering technology, CNIO and CNIC researchers have shown that it is possible to obtain such chromosomal translocations. The CRISPR-Cas9 system is extremely simple to introduce a cut at the desired locus, easier to design, and cheaper than many other systems. Using the CRISPR-Cas9 system, Ramirez and his colleagues reproduced the translocations observed in Ewing&rsquo;s Sarcoma (ES) and Acute Myeloid Leukemia (AML) patient cell lines in HEK293 cells and also generated the ES translocation in human mesenchymal stem cells and the AML translocation in umbilical cord blood cells.</p><p>By focusing on chromosomal translocation without the confounding characteristics of established cell lines, these new cells lines should help answer the fundamental question of what causes a cell to become cancerous. Ramirez and his team now look forward to modeling other chromosome translocations in a variety of cell types.</p><p>Reference:</p><p>http://en.wikipedia.org/wiki/Chromosomal_translocation</p><p>http://www.nature.com/ncomms/2014/140603/ncomms4964/abs/ncomms4964.html<br /><br /></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/3965/ruby-and-bioruby-tutorials</guid>
	<pubDate>Mon, 26 Aug 2013 17:18:28 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/3965/ruby-and-bioruby-tutorials</link>
	<title><![CDATA[Ruby and BioRuby Tutorials]]></title>
	<description><![CDATA[<p>Collections of Ruby and BioRuby learning materials.</p>
<p>BioRuby paper link :&nbsp;<a href="http://bioinformatics.oxfordjournals.org/content/26/20/2617.abstract">http://bioinformatics.oxfordjournals.org/content/26/20/2617.abstract</a></p><p>Address of the bookmark: <a href="http://www.codeschool.com/paths/ruby" rel="nofollow">http://www.codeschool.com/paths/ruby</a></p>]]></description>
	<dc:creator>Jitendra Narayan</dc:creator>
</item>

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