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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/11030?offset=1220</link>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/42570/breeding-insight</guid>
	<pubDate>Wed, 06 Jan 2021 19:49:21 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/42570/breeding-insight</link>
	<title><![CDATA[Breeding Insight]]></title>
	<description><![CDATA[<p><span><span>Breeding Insight&nbsp;at Cornell University will leverage recent improvements in genomics and open source informatics components, and in&nbsp;partnership with small breeding programs, will enable these programs to harness&nbsp;&nbsp;powerful digital tools to accelerate their genetic gains</span></span></p>
<p><span>Breeding Insight is funded by&nbsp;the&nbsp;</span><span><a href="https://www.ars.usda.gov/about-ars/" target="_blank">U.S. Department of Agriculture (USDA) Agricultural Research Service (ARS)</a></span><span>&nbsp;through Cornell University. The USDA ARS delivers scientific solutions to national and global agricultural challenges. As a global leader&nbsp;in agricultural discovery through scientific excellence, ARS is committed to delivering cutting-edge, scientific tools and innovative solutions for American farmers, producers, industry, and communities to support the nourishment and well-being of all people; sustaining our nation&rsquo;s agroecosystems and natural resources; and ensuring the economic competitiveness and excellence of our agriculture.</span></p><p>Address of the bookmark: <a href="https://www.breedinginsight.org/" rel="nofollow">https://www.breedinginsight.org/</a></p>]]></description>
	<dc:creator>BioStar</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/45278/the-day-we-began-reading-the-dna-of-the-world</guid>
	<pubDate>Sat, 05 Sep 2026 01:43:21 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/45278/the-day-we-began-reading-the-dna-of-the-world</link>
	<title><![CDATA[The Day We Began Reading the DNA of the World]]></title>
	<description><![CDATA[<div>Picture waking up and knowing that in one lab, a scientist is reading the DNA of a whale. In another, a team is sequencing a rare plant. Meanwhile, researchers in India are decoding the genomes of different human populations.</div><div>&nbsp;</div><div>Many organisms. Many countries. All share one remarkable goal: to understand the genetic story of life.</div><div>DNA is nature's instruction manual, written with just four letters: A, T, C, and G. For years, scientists could only read small sections of this huge book. Now, new sequencing technology lets us read entire genomes like never before.</div><div>&nbsp;</div><div>One of the most ambitious projects is the Earth BioGenome Project (EBP). Its goal is to create reference genomes for about 1.5 million known eukaryotic species. This project links genome research across continents, species, and scientific fields.</div><div>&nbsp;</div><div>But this story goes beyond just animals and plants.</div><div>&nbsp;</div><div><strong>A New Chapter in Human Genomics</strong></div><div>&nbsp;</div><div>Large human genome projects are changing how we understand our own genetic diversity.</div><div>India's GenomeIndia project has sequenced thousands of people from different populations. This work is uncovering genetic variation that global databases have often missed.</div><div>&nbsp;</div><div>Similar population-scale effSimilar large-scale projects are happening worldwide. The All of Us Research Program in the United States, Europe's 1+ Million Genomes initiative, South Korea's national genomic data program, and projects in Saudi Arabia, Australia, and Singapore are all building huge genomic resources.collect DNA.</div><div>&nbsp;</div><div>The real goal is to link genomes with health, disease, and other biological information. This creates a base for more accurate research and, in time, more personalized medicine.</div><div>&nbsp;</div><div><strong>A Race Against Time</strong></div><div>&nbsp;</div><div>There is also an important twist.</div><div>&nbsp;</div><div>We are sequencing Earth's biodiversity even as many species face growing environmental threats.</div><div>A genome alone cannot save a species, but it does keep important information about its biology, evolution, and genetic diversity. This knowledge helps scientists understand risks, guide conservation, and find traits that could help agriculture or medicine.</div><div>&nbsp;</div><div>Projects like the Darwin Tree of Life, which studies species in Britain and Ireland, and the African BioGenome Project, which is growing genomics work across Africa, are key parts of this worldwide effort.</div><div>&nbsp;</div><div>Projects to Watch</div><ol>
<li>Earth BioGenome Project (EBP) - A global effort to sequence and annotate roughly 1.5 million known eukaryotic species and create a comprehensive reference library of Earth's biodiversity.</li>
<li>Vertebrate Genomes Project (VGP) - Focuses on producing high-quality reference genomes for vertebrate species, providing a major foundation for the wider Tree of Life.</li>
<li>Darwin Tree of Life - A UK and Ireland initiative aiming to sequence approximately 70,000 species, creating a detailed genomic map of regional biodiversity.</li>
<li>African BioGenome Project (AfricaBP) - A pan-African initiative focused on sequencing Africa's biodiversity while strengthening genomics and bioinformatics capacity across the continent.</li>
<li>European Reference Genome Atlas (ERGA) - A European effort to generate high-quality reference genomes for Europe's biodiversity and connect national sequencing efforts.</li>
<li>Canada BioGenome Project - Building reference genomes for Canadian biodiversity, supporting conservation, research and the study of ecosystems.</li>
<li>California Conservation Genomics Project - Uses genomics to understand and protect California's biodiversity and help inform conservation decisions.</li>
<li>Bat1K - An ambitious global effort to sequence the genomes of all known bat species, helping scientists study their evolution, longevity, immunity and unique biology.</li>
<li>Bird 10,000 (B10K) - A global project aiming to create genome resources covering the world's bird diversity and reconstruct avian evolutionary history.</li>
<li>Global Invertebrate Genomics Alliance (GIGA) - Builds genomic resources for the enormous and genetically diverse world of invertebrates.</li>
<li>GenomeIndia - India's national human-genome initiative, designed to capture the country's extraordinary population diversity and create a reference resource for Indian genomics.</li>
<li>All of Us Research Program - A US national research program combining genomic information with health and lifestyle data at population scale.</li>
<li>1+ Million Genomes / Genome of Europe - A European effort to enable secure, cross-border use of genomic and health data and develop genome-scale resources involving more than one million people.</li>
<li>Korea National Integrated Bio Big Data Project - South Korea's large-scale national effort combining genomic and health information from a very large population cohort.</li>
<li>Saudi Genome Program - A national genomics initiative focused on genetic diseases, population genomics and precision medicine in Saudi Arabia.</li>
<li>Australian Genomics / Genomics Health Futures Mission - Australia's growing investment in genomic medicine, rare disease research and population-scale health genomics.</li>
</ol><div><strong>The Library of Life</strong></div><div>&nbsp;</div><div>The fuThe future of genomics is not just about sequencing one genome at a time. Now, it is about creating a worldwide network of genomes&mdash;human and non-human, individual and species&mdash;linked by powerful databases and advanced computational tools.ine a library without shelves.</div><div>&nbsp;</div><div>In this library, the books are genomes. The pages are made of DNA. Scientists and machines are the readers. And this library is still being written. Each genome sequenced today adds a new page to the story of life and helps us better understand our place in it.</div>]]></description>
	<dc:creator>Jitendra Narayan</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/17924/software-developed-in-pevsner-lab</guid>
	<pubDate>Mon, 06 Oct 2014 12:41:26 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/17924/software-developed-in-pevsner-lab</link>
	<title><![CDATA[Software developed in pevsner lab]]></title>
	<description><![CDATA[<div>
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<p><a href="http://pevsnerlab.kennedykrieger.org/dragon.htm">DRAGON</a>: Database Referencing of Array Genes Online</p>
<p><a href="http://pevsnerlab.kennedykrieger.org/php/node/96">SNOMAD</a>: Standardization and Normalization of Microarray Data</p>
<p><a href="http://pevsnerlab.kennedykrieger.org/php/node/70">SNPduo</a>: SNP Analysis Between Two Individuals</p>
<p><a href="http://pevsnerlab.kennedykrieger.org/php/node/71">SNPtrio</a>: Analyzing and Visualizing and Inheritance Patterns in Trios</p>
<p><a href="http://pevsnerlab.kennedykrieger.org/php/node/64">SNPscan</a>: Data Analysis and Visualization of SNP Data</p>
<p><a href="http://pevsnerlab.kennedykrieger.org/php/node/64">pediSNP</a>: Analyze SNP Data From a Pedigree of Two Generations</p>
<p><a href="http://pevsnerlab.kennedykrieger.org/php/node/73">kcoeff</a>: Calculate Cotterman Coefficients of SNP Genotype Data</p>
<p><a href="http://pevsnerlab.kennedykrieger.org/php/node/113">triPOD:</a> Detects chromosomal abnormalities in parent-child trio-based microarray data</p>
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</div><p>Address of the bookmark: <a href="http://pevsnerlab.kennedykrieger.org/php/?q=software" rel="nofollow">http://pevsnerlab.kennedykrieger.org/php/?q=software</a></p>]]></description>
	<dc:creator>Robert M Willioms</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/44661/lovis4u-locus-visualisation-tool-for-comparative-genomics</guid>
	<pubDate>Tue, 17 Sep 2024 02:30:57 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/44661/lovis4u-locus-visualisation-tool-for-comparative-genomics</link>
	<title><![CDATA[LoVis4u: Locus Visualisation tool for comparative genomics]]></title>
	<description><![CDATA[<p dir="auto"><a href="https://github.com/art-egorov/lovis4u/blob/main/docs/img/lovis4u_logo.png" target="_blank"><img src="https://github.com/art-egorov/lovis4u/raw/main/docs/img/lovis4u_logo.png" alt="image" width="300" style="border: 0px; border: 0px;"></a></p>
<div dir="auto">
<h2 dir="auto">Description</h2>
<a href="https://github.com/art-egorov/lovis4u#description"></a></div>
<p dir="auto"><span>LoVis4u</span>&nbsp;is a bioinformatics tool for&nbsp;<span>Lo</span>ci&nbsp;<span>Vis</span>ualisation.</p>
<p dir="auto"><span>LoVis4u, a command-line tool and Python API designed for highly customizable and fast visualisation of multiple genomic loci. LoVis4u generates vector images in PDF format based on annotation data from GenBank or GFF files. It is capable of visualising entire genomes of bacteriophages as well as plasmids and user-defined regions of longer prokaryotic genomes. Additionally, LoVis4u offers optional data processing steps to identify and highlight accessory and core genes in input sequences.</span></p>
<p dir="auto">https://art-egorov.github.io/lovis4u/</p>
<p dir="auto">&nbsp;</p><p>Address of the bookmark: <a href="https://github.com/art-egorov/lovis4u" rel="nofollow">https://github.com/art-egorov/lovis4u</a></p>]]></description>
	<dc:creator>LEGE</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/43101/luigi-a-python-package-that-helps-you-build-complex-pipelines-of-batch-jobs</guid>
	<pubDate>Thu, 24 Jun 2021 05:43:31 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/43101/luigi-a-python-package-that-helps-you-build-complex-pipelines-of-batch-jobs</link>
	<title><![CDATA[Luigi: a Python package that helps you build complex pipelines of batch jobs.]]></title>
	<description><![CDATA[<p>Luigi is a Python (3.6, 3.7, 3.8, 3.9 tested) package that helps you build complex pipelines of batch jobs. It handles dependency resolution, workflow management, visualization, handling failures, command line integration, and much more.</p>
<p>Run <code>pip install luigi</code> to install the latest stable version from <a href="https://pypi.python.org/pypi/luigi">PyPI</a>. <a href="https://luigi.readthedocs.io/en/stable/">Documentation for the latest release</a> is hosted on readthedocs.</p>
<p>Run <code>pip install luigi[toml]</code> to install Luigi with <a href="https://luigi.readthedocs.io/en/stable/configuration.html">TOML-based configs</a> support.</p><p>Address of the bookmark: <a href="https://github.com/spotify/luigi" rel="nofollow">https://github.com/spotify/luigi</a></p>]]></description>
	<dc:creator>Neel</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/120/user</guid>
	<pubDate>Wed, 10 Jul 2013 14:41:49 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/120/user</link>
	<title><![CDATA[useR!]]></title>
	<description><![CDATA[<p><span>The R project actively supports two conference series, organized regularly by members from the R community: useR! - providing a forum to the R user community - and DSC - a platform for developers of statistical software.</span></p><p><span>Recently useR! conference have been organized&nbsp;<span>University of Castilla-La Mancha, Albacete, Spain.</span></span></p><p><a href="http://www.edii.uclm.es/~useR-2013//">http://www.edii.uclm.es/~useR-2013//</a></p><p>&nbsp;</p>]]></description>
	<dc:creator>Jitendra Narayan</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/5894/rna-seq-data-pathway-and-gene-set-analysis-workflows</guid>
	<pubDate>Fri, 25 Oct 2013 08:00:48 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/5894/rna-seq-data-pathway-and-gene-set-analysis-workflows</link>
	<title><![CDATA[RNA-Seq Data Pathway and Gene-set Analysis Workflows]]></title>
	<description><![CDATA[<p>It describe the GAGE (Luo et al., 2009) /Pahview (Luo and Brouwer, 2013) workflows on&nbsp;RNA-Seq data pathway analysis and gene-set analysis.&nbsp;<span>The gage package (2.12.0) now includes a new tutorial, &ldquo;RNA-Seq Data Pathway and Gene-set Analysis Workflows&ldquo;.</span></p><p>First cover a full workflow from preparation, reads counting, data preprocessing, gene set test, to pathway visualization in about 40 lines of codes. The same workflow can be used for GO analysis or other types of gene set analysis too. We also describe joint workflows, i.e. to do gene-level analysis using one of the major RNA-Seq analysis tools, DEseq/DEseq2, edgeR, limma and Cufflinks, and feed the results into GAGE/Pahview for pathway analysis or visualization. All these workflows are implemented in R/Bioconductor.</p><p>The work ows cover the most common situations and issues for RNA-Seq data pathway analysis. Issues like&nbsp;data quality assessment are relevant for data analysis in general yet out the scope of this tutorial. Although we&nbsp;focus on RNA-Seq data here, but pathway analysis work ow remains similar for microarray, particularly step&nbsp;3-4 would be the same. Please check gage and pathview vigenttes for details.</p><p>Note: You need to update to current release versions of R(3.0.2)/ Bioconductor(2.13) to use all the features.&nbsp;</p><p>Reference:&nbsp;</p><p>Please check it out:<br /><a href="http://bioconductor.org/packages/release/bioc/html/gage.html">http://bioconductor.org/packages/release/bioc/html/gage.html</a><br /><a href="http://bioconductor.org/packages/release/bioc/vignettes/gage/inst/doc/RNA-seqWorkflow.pdf">http://bioconductor.org/packages/release/bioc/vignettes/gage/inst/doc/RNA-seqWorkflow.pdf</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/33592/circular-plots-in-r</guid>
	<pubDate>Mon, 19 Jun 2017 06:20:27 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/33592/circular-plots-in-r</link>
	<title><![CDATA[Circular plots in R]]></title>
	<description><![CDATA[<div>
<p><strong>Circular plots</strong>&nbsp;are useful to represent complicated informations. They are used in 2 specific cases: when you have long axis and numerous categories, and when you want to show relationships between elements. The&nbsp;<a href="http://circos.ca/images/samples/" target="_blank">circos gallery</a>&nbsp;displays several examples of circular plots, what gives a nice overview of the possibilities. Circos is the most famous</p>
</div>
<div>
<p>tool to create circular plots. Thanks to&nbsp;<a href="https://www.linkedin.com/in/zuguanggu" target="_blank">Zuguang Gu</a>, the&nbsp;<a href="https://cran.r-project.org/web/packages/circlize/vignettes/circlize.pdf" target="_blank">Circlize library</a>&nbsp;makes the circos functions available in R! It implements low-level graphic functions for adding common graphics in a circular layout. This page aims to learn you how to use the library, so I strongly advise to read the graphics in the proposed order!</p>
<p><img src="http://www.r-graph-gallery.com/wp-content/uploads/2016/03/122_Circlize_package.png" width="480" height="480" alt="image" style="border: 0px;"></p>
</div>
<p>http://www.r-graph-gallery.com/portfolio/circular-plot/</p><p>Address of the bookmark: <a href="http://www.r-graph-gallery.com/portfolio/circular-plot/" rel="nofollow">http://www.r-graph-gallery.com/portfolio/circular-plot/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/34396/pore-an-r-package-for-the-visualization-and-analysis-of-nanopore-sequencing-data</guid>
	<pubDate>Thu, 23 Nov 2017 09:55:57 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/34396/pore-an-r-package-for-the-visualization-and-analysis-of-nanopore-sequencing-data</link>
	<title><![CDATA[poRe: an R package for the visualization and analysis of nanopore sequencing data]]></title>
	<description><![CDATA[<p><strong>Motivation:</strong>&nbsp;The Oxford Nanopore MinION device represents a unique sequencing technology. As a mobile sequencing device powered by the USB port of a laptop, the MinION has huge potential applications. To enable these applications, the bioinformatics community will need to design and build a suite of tools specifically for MinION data.</p>
<p><strong>Results:</strong>&nbsp;Here we present poRe, a package for R that enables users to manipulate, organize, summarize and visualize MinION nanopore sequencing data. As a package for R, poRe has been tested on Windows, Linux and MacOSX. Crucially, the Windows version allows users to analyse MinION data on the Windows laptop attached to the device.</p>
<p><strong>Availability and implementation:</strong>&nbsp;poRe is released as a package for R at&nbsp;<a href="http://sourceforge.net/projects/rpore/" target="">http://sourceforge.net/projects/rpore/</a>&nbsp;. A tutorial and further information are available at&nbsp;<a href="https://sourceforge.net/p/rpore/wiki/Home/" target="">https://sourceforge.net/p/rpore/wiki/Home/</a></p>
<p><strong>Contact:</strong><a href="mailto:mick.watson@roslin.ed.ac.uk" target="">mick.watson@roslin.ed.ac.uk</a></p><p>Address of the bookmark: <a href="https://academic.oup.com/bioinformatics/article/31/1/114/2365693" rel="nofollow">https://academic.oup.com/bioinformatics/article/31/1/114/2365693</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/35437/dupradar-package</guid>
	<pubDate>Sun, 04 Feb 2018 14:28:57 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/35437/dupradar-package</link>
	<title><![CDATA[dupRadar package]]></title>
	<description><![CDATA[<p><span>The&nbsp;</span><em>dupRadar</em><span>&nbsp;package gives an insight into the duplication problem by graphically relating the gene expression level and the duplication rate present on it. Thus, failed experiments can be easily identified at a glance</span></p><p>Address of the bookmark: <a href="https://bioconductor.org/packages/3.7/bioc/vignettes/dupRadar/inst/doc/dupRadar.html" rel="nofollow">https://bioconductor.org/packages/3.7/bioc/vignettes/dupRadar/inst/doc/dupRadar.html</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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