BOL: Related items

Microscope

Jitendra Narayan — Fri, 04 Mar 2016 05:26:31 -0600

Microscope Platform user documentation.

The MicroScope platform is available at this URL:

https://www.genoscope.cns.fr/agc/microscope

Address of the bookmark: http://microscope.readthedocs.org/en/latest/index.html

Heap: a highly sensitive and accurate SNP detection tool for low-coverage high-throughput sequencing data

Jit — Thu, 19 Apr 2018 08:06:03 -0500

Heap, that enables robustly sensitive and accurate calling of SNPs, particularly with a low coverage NGS data, which must be aligned to the reference genome sequences in advance. To reduce false positive SNPs, Heap determines genotypes and calls SNPs at each site except for sites at the both end of reads or containing a minor allele supported by only one read. Performance comparison with existing tools showed that Heap achieved the highest F-scores with low coverage (7X) restriction-site associated DNA sequencing reads of sorghum and rice individuals. This will facilitate cost-effective GWAS and GP studies in this NGS era. Code and documentation of Heap are freely available from https://github.com/meiji-bioinf/heap and our web site (http://bioinf.mind.meiji.ac.jp/lab/en/tools.html).

Address of the bookmark: https://github.com/meiji-bioinf/heap

PostDoc at IISER -TVM

Fri, 26 Feb 2016 03:53:05 -0600

Postdoctoral Fellowship/ Research Associateship

Eligibility : M Phil / Phd

Location : Thiruvananthapuram

Last Date : 30 Apr 2016

Hiring Process : Face to Face Interview
IISER -TVM

The Postdoctoral Fellowship/Research Associateship is a full-time, contractual position for highly qualified young scientists to carry out research at CCMS, IISER-TVM.

Research areas at the Centre

Quantum Chemistry/ Computational Fluid Dynamics/Condensed Matter Physics (Theory)/Genomics/Genetics/Gravitational Waves

Qualifications: PhD in Bioinformatics / Biophysics / Physics / Astrophysics / Chemistry / Mathematics / Engineering (Mechanical/Aerospace) Those who are in the final stages of their Ph.D. thesis submission are also eligible to apply. However, those candidates must have submitted the thesis at the time of the interview.

Experience: Applicants should have at least three peer reviewed publications and relevant experience in the research area they are applying for.

No. of positions: 5

Age limit: 35 yrs or below. A relaxation of 5 yrs will be applicable to candidates belonging to SC/ST/OBC and women candidates

Salary: The Fellowship carries a remuneration of INR Rs. 5,18,000 - Rs. 5,76,000 per annum (including HRA). The postdoctoral fellowship may not be held concurrently with any other national or international fellowships. It is also not transferable to any other fellowship
How to apply

Applications should reach the Head, CCMS, IISER Thiruvananthapuram,CET Campus, Engineering College PO,Thiruvananthapuram 695016 on or before April 30, 2016 by e-mail to ccms@iisertvm.ac.in by mentioning the research area name in the subject line.

More at http://www.iisertvm.ac.in/openings/read_opening/150.phpx

Manta: rapid detection of structural variants and indels for germline and cancer sequencing applications.

Jit — Mon, 28 May 2018 09:41:39 -0500

Manta calls structural variants (SVs) and indels from mapped paired-end sequencing reads. It is optimized for analysis of germline variation in small sets of individuals and somatic variation in tumor/normal sample pairs. Manta discovers, assembles and scores large-scale SVs, medium-sized indels and large insertions within a single efficient workflow.

Address of the bookmark: https://github.com/Illumina/manta

NextSV: a meta-caller for structural variants from low-coverage long-read sequencing data

Jit — Mon, 06 Aug 2018 17:24:53 -0500

NextSV, a meta SV caller and a computational pipeline to perform SV calling from low coverage long-read sequencing data. NextSV integrates three aligners and three SV callers and generates two integrated call sets (sensitive/stringent) for different analysis purpose. The output of NextSV is in ANNOVAR-compatible bed format. Users can easily perform downstream annotation using ANNOVAR and disease gene discovery using Phenolyzer.

Address of the bookmark: https://github.com/Nextomics/NextSV

Indexcov: fast coverage quality control for whole-genome sequencing

Jit — Wed, 29 Aug 2018 09:20:46 -0500

indexcov, an efficient estimator of whole-genome sequencing coverage to rapidly identify samples with aberrant coverage profiles, reveal large-scale chromosomal anomalies, recognize potential batch effects, and infer the sex of a sample. Indexcov is available at https://github.com/brentp/goleft under the MIT license.

Address of the bookmark: https://github.com/brentp/goleft

lordFAST: sensitive and Fast Alignment Search Tool for LOng noisy Read sequencing Data

BioJoker — Tue, 27 Nov 2018 04:43:57 -0600

lordFAST is a sensitive tool for mapping long reads with high error rates. lordFAST is specially designed for aligning reads from PacBio sequencing technology but provides the user the ability to change alignment parameters depending on the reads and application.

lordFAST, a novel long-read mapper that is specifically designed to align reads generated by PacBio and potentially other SMS technologies to a reference. lordFAST not only has higher sensitivity than the available alternatives, it is also among the fastest and has a very low memory footprint.

Address of the bookmark: https://github.com/vpc-ccg/lordfast

flo

Jitendra Narayan — Wed, 10 Feb 2016 10:52:32 -0600

flo - same species annotations lift over pipeline

Lift over is the process of transferring annotations from one genome assembly to another. Usually lift over is done because there is a new, improved genome assembly for the species and good quality annotations (maybe manually curated or experimentally verified) are available on the old assembly.

The idea is simple: align the new assembly with the old one (e.g., with BLAT), process the alignment data to define how a coordinate or coordinate range on the old assembly should be transformed to the new assembly (e.g., as a chain file), transform the coordinates (e.g., with liftOver).

https://github.com/wurmlab/flo

Address of the bookmark: https://github.com/wurmlab/flo

Flye: Fast and accurate de novo assembler for single molecule sequencing reads

Rahul Nayak — Sat, 06 Jul 2019 03:48:22 -0500

Flye is a de novo assembler for single molecule sequencing reads, such as those produced by PacBio and Oxford Nanopore Technologies. It is designed for a wide range of datasets, from small bacterial projects to large mammalian-scale assemblies. The package represents a complete pipeline: it takes raw PB / ONT reads as input and outputs polished contigs. Flye also includes a special mode for metagenome assembly.

Address of the bookmark: https://github.com/fenderglass/Flye

Project Assistant/ JRF at North Eastern Hill University

Fri, 12 Feb 2016 09:23:01 -0600

Project Assistant/ JRF

Eligibility : ME/M.Tech, Any Graduate, MSc

Location : Shillong

Last Date : 23 Feb 2016

Hiring Process : Face to Face Interview
North Eastern Hill University

Project Assistant/ JRF Jobs recruitment in North Eastern Hill University on temporary basis

Project Title : "Next Generation Sequencing (NGS)-based de novo assembly of expressed transcripts and genome information of Orchids in North-East India"

Project Assistant

No. of Post : 01

Qualifications : Graduation

Desirable : Experience of working in a Life Science/Plant Biotechnology lab. and familiarity with computers and field work viz. collection of samples.

JRF

No. of Post : 01

Qualifications : M.Tech/M.Sc in Life Sciences/Botany/Biotechnology/ Bioinformatics;

Desirable : Aptitude for Bioinformatics and Computer Programming/ Next generation sequencing data analysis
How to apply

The applications through email bicnehu@gmail.com or post must reach the Dr. Devendra Kumar Biswal, Co-Principal Investigator (Co-PI) within 15 days from the date of publication of this advertisement.

More at http://www.nehu.ac.in/Advertisements/projectVacancy.php