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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/11399?offset=1080</link>
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	<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/26356/spines</guid>
	<pubDate>Tue, 09 Feb 2016 05:07:15 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/26356/spines</link>
	<title><![CDATA[Spines]]></title>
	<description><![CDATA[<div id="content-header">
<h1>Spines</h1>
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<div id="node-1301">
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<div>
<p><a href="http://www.broadinstitute.org/ftp/distribution/software/spines/"><em>Spines</em></a> is a collection of software tools, developed and used by the Vertebrate Genome Biology Group at the Broad Institute. It provides basic data structures for efficient data manipulation (mostly genomic sequences, alignments, variation etc.), as well as specialized tool sets for various analyses. It also features three sequence alignment packages: <em>Satsuma,</em> a highly parallelized program for high-sensitivity, genome-wide synteny; <em>Papaya,</em> an all-purpose alignment tool for less diverged sequences; and <em>SLAP,</em> a context-sensitive local aligner for diverged sequences with large gaps.</p>
<p>Access <em>Spines</em> <a href="http://www.broadinstitute.org/ftp/distribution/software/spines/">here</a>.</p>
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</div>
</div>
<p>http://www.broadinstitute.org/science/programs/genome-biology/spines</p><p>Address of the bookmark: <a href="http://www.broadinstitute.org/science/programs/genome-biology/spines" rel="nofollow">http://www.broadinstitute.org/science/programs/genome-biology/spines</a></p>]]></description>
	<dc:creator>Jitendra Narayan</dc:creator>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/26380/hicdat</guid>
	<pubDate>Fri, 12 Feb 2016 05:23:44 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/26380/hicdat</link>
	<title><![CDATA[HiCdat]]></title>
	<description><![CDATA[<p>HiCdat: a fast and easy-to-use Hi-C data analysis tool</p>
<p>HiCdat is easy-to-use and provides solutions starting from aligned reads up to in-depth analyses. Importantly, HiCdat is focussed on the analysis of larger structural features of chromosomes, their correlation to genomic and epigenomic features, and on comparative studies. It uses simple input and output formats and can therefore easily be integrated into existing workflows or combined with alternative tools.</p>
<p>More at http://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-015-0678-x</p><p>Address of the bookmark: <a href="https://github.com/MWSchmid/HiCdat" rel="nofollow">https://github.com/MWSchmid/HiCdat</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/26409/ucsc-genome-browser-and-blat-software</guid>
	<pubDate>Thu, 18 Feb 2016 03:18:57 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/26409/ucsc-genome-browser-and-blat-software</link>
	<title><![CDATA[UCSC Genome Browser and Blat software !]]></title>
	<description><![CDATA[<p>This directory contains Genome Browser and Blat application binaries built for standalone <br>command-line use on various supported Linux and UNIX platforms. To determine which set of binaries <br>to download, type "uname -a" on the command line to display your machine type. In most cases the <br>usage statement for the application can be viewed by running the binary with no arguments. <br><br>The UCSC Genome Browser and Blat software are free for academic, nonprofit, and personal use. A <br>license is required for commercial download and installation of these binaries, with the exception <br>of items built from the following source code directories, which are freely available for all uses:<br><br>&nbsp;- kent/src/utils (includes big* tools)<br>&nbsp;- kent/src/lib<br>&nbsp;- kent/src/hg/autoSql<br>&nbsp;- kent/src/hg/autoXml<br><br>For information about commercial licensing of the Genome Browser software, see <br>http://genome.ucsc.edu/license/. The Blat and In-Silico PCR software may be commercially<br>licensed through Kent Informatics (http://www.kentinformatics.com).</p>
<p>More at http://hgdownload.cse.ucsc.edu/admin/exe/</p><p>Address of the bookmark: <a href="http://hgdownload.cse.ucsc.edu/admin/exe/" rel="nofollow">http://hgdownload.cse.ucsc.edu/admin/exe/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/26456/the-mills-lab</guid>
  <pubDate>Wed, 24 Feb 2016 16:18:38 -0600</pubDate>
  <link></link>
  <title><![CDATA[The Mills lab]]></title>
  <description><![CDATA[
<p>The laboratory is focused on the discovery and analysis of structural variation (SVs) from genomic sequence data. As part of the 1000 Genomes Project and other endeavors, we have helped produce initial fine-scale maps using a variety of SV discovery approaches including: (i) paired-end mapping (or read pair analysis) based on abnormally mapped pairs of clone ends; (ii) read-depth analysis, which detects deletions and duplications through analysis of the read depth-of-coverage; (iii) split read analysis, which detects SVs by evaluating gapped sequence alignments; and (iv) sequence assembly, which enables the discovery of novel (non-reference) sequence insertions.</p>

<p>http://millslab.org/research.html</p>
]]></description>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/26919/pear-a-fast-and-accurate-illumina-paired-end-read-merger</guid>
	<pubDate>Wed, 06 Apr 2016 13:27:23 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/26919/pear-a-fast-and-accurate-illumina-paired-end-read-merger</link>
	<title><![CDATA[PEAR: a fast and accurate Illumina Paired-End reAd mergeR]]></title>
	<description><![CDATA[<p><strong>PEAR</strong>&nbsp;is an ultrafast, memory-efficient and highly accurate pair-end read merger. It is fully parallelized and can run with as low as just a few kilobytes of memory.</p>
<p>PEAR evaluates all possible paired-end read overlaps and without requiring the target fragment size as input. In addition, it implements a statistical test for minimizing false-positive results. Together with a highly optimized implementation, it can merge millions of paired end reads within a couple of minutes on a standard desktop computer.</p>
<p>More at&nbsp;http://www.exelixis-lab.org/web/software/pear</p>
<p>Paper:&nbsp;http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933873/</p><p>Address of the bookmark: <a href="http://www.exelixis-lab.org/web/software/pear" rel="nofollow">http://www.exelixis-lab.org/web/software/pear</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/27211/srbioinformatics-analyst-ngs-ocimumbio</guid>
  <pubDate>Mon, 02 May 2016 04:41:22 -0500</pubDate>
  <link></link>
  <title><![CDATA[Sr.Bioinformatics Analyst (NGS) @ OcimumBio]]></title>
  <description><![CDATA[
<p>Sr.Bioinformatics Analyst (NGS)</p>

<p>Experience Required: 3-5 years of experience<br />No of Positions : Multiple<br />Qualifications: Candidates with minimum qualification as M.Sc Bioinformatics with 3-5  years of experience in Life sciences R&amp;D or Pharma Industry.<br />Ph.D candidates with research experience in Bioinformatics with publications in International journal and minimum 2 years of  industry experience in clinical genomics will be preferred for this position.</p>

<p>Requirement:</p>

<p>1.  Must have basic understanding of molecular biology and Genomics.<br />2. Experience in application development or must have expertise in programming using either of Perl/Python.<br />3.  Experience in statistical programming using R/Bioconductor/Matlab.<br />4. Strong concept in statistical and mathematical modelling.<br />5.  Experience in designing and developing the bioinformatics pipeline.<br />6.  Must have minimum 2+ years of hands on experience in NSG data analysis such as RNA-Seq,Exome-Seq ,Chip-Seq and downstream analysis.<br />7. Knowledge in WGS ,WES, Targeted re-sequencing,GWAS and population genomics will be preferred.<br />8. Must have experience working on opensource software/Framework and commercial software for NGS data analysis and reporting.<br />9. Should be aware of handling big data and guiding team members on multiple projects simultaneously.<br />More at http://www.ocimumbio.com/careers1/<br />10. Should have experience coordinating with different groups of clinical research scientist for various project requirements.<br />11. Ability to work as team as well as independently with minimal support.</p>
]]></description>
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<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/27240/bioinformatics-tutor-at-pgimer</guid>
  <pubDate>Wed, 04 May 2016 08:40:26 -0500</pubDate>
  <link></link>
  <title><![CDATA[Bioinformatics Tutor at PGIMER]]></title>
  <description><![CDATA[
<p>Postgraduate Institute of Medical Education and Research (PGIMER) - Chandigarh, Chandigarh<br />₹9,300 - ₹34,800 a month<br />Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh invites Online Applications for recruitment of following Group 'A', 'B' and 'C' posts. The closing date for submission of online applications is up to 12th May 2016.</p>

<p>No of Vacancies: 01<br />Pay Scale: Rs. 9300-34800 + Grade Pay Rs. 4600/-</p>

<p>Educational Qualification and Experience: (From Recognized University / Institute) M.Sc. in Biotechnology, Molecular Biology, Human Genomics / Biochemistry / Biophysics.</p>

<p>Age Limit: 18-50 years</p>

<p>Please see Detailed Advertisement Link for full info: https://drive.google.com/file/d/0Bz3xO6e_7OeeZllINnRyWlN5UFE/view</p>
]]></description>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/27291/summer-internship-positions-at-dupont</guid>
  <pubDate>Wed, 11 May 2016 08:05:54 -0500</pubDate>
  <link></link>
  <title><![CDATA[Summer internship positions at DuPont]]></title>
  <description><![CDATA[
<p>DuPont Industrial Biosciences has several summer internship positions<br />for undergrads available. We are looking for driven and creative interns<br />to conduct research in the following areas:</p>

<p>· Enzyme immobilization supports for select enzyme systems.</p>

<p>· New tools for microbial strain and genome engineering using<br />state-of-the-art methodologies.</p>

<p>· Rapid high throughput assays to screen microorganisms from various<br />sources for enzymatic activities of interest.</p>

<p>· High throughput combinatorial approaches to the formulation of growth<br />media in support of microbial enrichments, strain isolations and growth<br />optimization.</p>

<p>· Meta-transcriptomics for the discovery of new enzymes.</p>

<p>· Strain adaptation techniques in defined chemostat environments for<br />microbial strain development.</p>

<p>The internships are based at the Experimental Station R&amp;D Center in<br />Wilmington, DE.</p>

<p>If interested, apply fast!</p>

<p>For more information and to apply, go to:</p>

<p>http://careers.dupont.com/jobsearch/job-details/industrial-biosciences-summer-internship/008549W-10/</p>
]]></description>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/27321/slurm-basics</guid>
	<pubDate>Fri, 13 May 2016 04:42:24 -0500</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/27321/slurm-basics</link>
	<title><![CDATA[SLURM basics !]]></title>
	<description><![CDATA[<p><a href="http://bioinformaticsonline.com/bookmarks/view/27238/slurm" target="_blank">SLURM</a> is a queue management system and stands for Simple Linux Utility for Resource Management. SLURM was developed at the Lawrence Livermore National Lab and currently runs some of the largest compute clusters in the world.</p><p>SLURM is similar in many ways to most other queue systems. You write a batch script then submit it to the queue manager. The queue manager then schedules your job to run on the queue (or partition in SLURM parlance) that you designate. Below we will provide an outline of how to submit jobs to SLURM, how SLURM decides when to schedule your job and how to monitor progress.</p><p>SLURM has a number of valuable features compared to other job management systems:</p><ul>
<li><em>Kill and Requeue</em> SLURM&rsquo;s ability to kill and requeue is superior to that of other systems. It waits for jobs to be cleared before scheduling the high priority job. It also does kill and requeue on memory rather than just on core count.</li>
<li><em>Memory</em> Memory requests are sacrosanct in SLURM. Thus the amount of memory you request at run time is guaranteed to be there. No one can infringe on that memory space and you cannot exceed the amount of memory that you request.</li>
<li><em>Accounting Tools</em> SLURM has a back end database which stores historical information about the cluster. This information can be queried by the users who are curious about how much resources they have used.</li>
</ul><p><strong>Summary of SLURM commands</strong></p><p>The table below shows a summary of SLURM commands. These commands are described in more detail below along with links to the SLURM doc site.</p><table>
<tbody>
<tr><th>&nbsp;</th><th>SLURM</th><th>SLURM Example</th></tr>
<tr>
<td>Submit a batch serial job</td>
<td><a href="http://slurm.schedmd.com/sbatch.html">sbatch</a></td>
<td><code>sbatch runscript.sh</code></td>
</tr>
<tr>
<td>Run a script interatively</td>
<td><a href="http://slurm.schedmd.com/srun.html">srun</a></td>
<td><code>srun --pty -p interact -t 10 --mem 1000 /bin/bash /bin/hostname</code></td>
</tr>
<tr>
<td>Kill a job</td>
<td><a href="http://slurm.schedmd.com/scancel.html">scancel</a></td>
<td><code>scancel 999999</code></td>
</tr>
<tr>
<td>View status of queues</td>
<td><a href="http://slurm.schedmd.com/squeue.html">squeue</a></td>
<td><code>squeue -u akitzmiller</code></td>
</tr>
<tr>
<td>Check current job by id</td>
<td><a href="http://slurm.schedmd.com/squeue.html">sacct</a></td>
<td><code>sacct -j 999999</code></td>
</tr>
</tbody>
</table>]]></description>
	<dc:creator>Radha Agarkar</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27461/maftools</guid>
	<pubDate>Sat, 21 May 2016 22:40:21 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27461/maftools</link>
	<title><![CDATA[mafTools]]></title>
	<description><![CDATA[<p><span>Bioinformatics tools for dealing with Multiple Alignment Format (MAF) files.</span></p><p>Address of the bookmark: <a href="https://github.com/dentearl/mafTools" rel="nofollow">https://github.com/dentearl/mafTools</a></p>]]></description>
	<dc:creator>Radha Agarkar</dc:creator>
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