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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/11735?offset=720</link>
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<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/12111/internship-program-with-arraygen-technolgies</guid>
  <pubDate>Sun, 22 Jun 2014 23:18:31 -0500</pubDate>
  <link></link>
  <title><![CDATA[Internship program with ArrayGen Technolgies]]></title>
  <description><![CDATA[
<p>Internship Program for Bioinformatics / Biotechnology Professionals Currently we offer positions to outstanding students interested in Next Generation Sequencing (NGS) data analysis. Applications are accepted throughout the year. Accepted students will be listed on web with their schedules. Accepted students can attend our future workshops and trainings freely at the specified venue.</p>

<p>Interested candidates may email their resume along with a cover letter to careers@arraygen.com</p>

<p>Official website: http://www.arraygen.com/</p>
]]></description>
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<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/41043/postdoctoral-scientist-genome-analytics-genome-bioinformatics-mf</guid>
  <pubDate>Sun, 16 Feb 2020 02:57:40 -0600</pubDate>
  <link></link>
  <title><![CDATA[Postdoctoral scientist genome analytics/ genome bioinformatics (m/f/*)]]></title>
  <description><![CDATA[
<p>https://www.uksh.de/jobs/Stellenangebote-nr-20190570-p-8.html<br />Your profile:<br />Degree in bioinformatics, biostatistics, or equivalent<br />Experience in the processing and analysis of large-scale genomics data using compute clusters / high-performance computing<br />Strong competence in working in Unix/Linux environments (shell)<br />Strong programming skills (in particular: Python, R, Perl)<br />Experience with using git and snakemake<br />Fluent English language skills, both spoken and written<br />Strong communication skills and motivation to work in a young, interdisciplinary, dynamic team</p>

<p>Additional Information:</p>

<p>If you have any questions about scientific aspects of this position, please contact Prof. Lars Bertram, head of LIGA (lars.bertram@uni-luebeck.de).</p>

<p>Please contact Ms. Anna Wolbert for further questions about administrative details (recruiting@uksh.de).</p>

<p>Weitere Informationen erhalten Sie auch unter www.uksh.de/karriere.</p>

<p>Wir freuen uns auf Ihre Bewerbung bis zum 15.03.2020 unter Angabe unserer Ausschreibungsnummer 20190570.119.CL.</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/42003/perl-one-liner-for-beginners</guid>
	<pubDate>Fri, 24 Jul 2020 05:58:28 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/42003/perl-one-liner-for-beginners</link>
	<title><![CDATA[Perl one-liner for beginners !]]></title>
	<description><![CDATA[<p>I often use the following arguments to perl:</p><ul>
<li>-e Makes the line of code be executed instead of a script</li>
<li>-n Forces your line to be called in a loop. Allows you to take lines from the diamond operator (or stdin)</li>
<li>-p Forces your line to be called in a loop. Prints $_ at the end</li>
</ul><p>&nbsp;</p><ul>
<li>This counts the number of quotation marks in each line and prints it
<div>
<blockquote>
<div>perl -ne&nbsp;'$cnt = tr/"//;print "$cnt\n"'&nbsp;inputFileName.txt</div>
</blockquote>
</div>
</li>
</ul><ul>
<li>Adds string to each line, followed by tab
<div>
<blockquote>
<div>perl -pe&nbsp;'s/(.*)/string\t$1/'&nbsp;inFile &gt; outFile</div>
</blockquote>
</div>
</li>
</ul><ul>
<li>Append a new line to each line
<div>
<blockquote>
<div>perl -pe&nbsp;'s//\n/'&nbsp;all.sent.classOnly &gt; all.sent.classOnly.sep</div>
</blockquote>
</div>
</li>
</ul><ul>
<li>Replace all occurrences of pattern1 (e.g. [0-9]) with pattern2
<div>
<blockquote>
<div>perl -p -i.bak -w -e&nbsp;'s/pattern1/pattern2/g'&nbsp;inputFile</div>
</blockquote>
</div>
</li>
</ul><ul>
<li>Go through file and only print words that do not have any uppercase letters.
<div>
<blockquote>
<div>perl -ne&nbsp;'print unless m/[A-Z]/'&nbsp;allWords.txt &gt; allWordsOnlyLowercase.txt</div>
</blockquote>
</div>
</li>
</ul><ul>
<li>Go through file, split line at each space and print words one per line.
<div>
<blockquote>
<div>perl -ne&nbsp;'print join("\n", split(/ /,$_));print("\n")'&nbsp;someText.txt &gt; wordsPerLine.txt</div>
</blockquote>
</div>
</li>
</ul><ul>
<li>or in other words, delete every character that is not a letter, white space or line end (replace with nothing)
<div>
<blockquote>
<div>perl -pne&nbsp;'s/[^a-zA-Z\s]*//g'&nbsp;text_withSpecial.txt &gt; text_lettersOnly.txt</div>
</blockquote>
</div>
</li>
</ul><ul>
<li>
<div>
<div>perl -pne&nbsp;'tr/[A-Z]/[a-z]/'&nbsp;textWithUpperCase.txt &gt; textwithoutuppercase.txt;</div>
</div>
</li>
</ul><ul>
<li>Print only the second column of the data when using tabular as a separator
<div>
<blockquote>
<div>perl -ne&nbsp;'@F = split("\t", $_); print "$F[1]";'&nbsp;columnFileWithTabs.txt &gt; justSecondColumn.txt</div>
</blockquote>
</div>
</li>
</ul><ul>
<li>
<div>One-Liner: Sort lines by their length
<blockquote>
<div>perl -e&nbsp;'print sort {length $a &lt;=&gt; length $b} &lt;&gt;'&nbsp;textFile</div>
</blockquote>
</div>
</li>
</ul><ul>
<li>One-Liner: Print second column, unless it contains a number
<blockquote>
<div>perl"&gt;perl -lane&nbsp;'print $F[1] unless $F[1] =~ m/[0-9]/'&nbsp;wordCounts.txt</div>
</blockquote>
</li>
</ul>]]></description>
	<dc:creator>BioStar</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/2791/ncbi-psi-blast-tutorial</guid>
	<pubDate>Fri, 23 Aug 2013 02:25:02 -0500</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/2791/ncbi-psi-blast-tutorial</link>
	<title><![CDATA[NCBI PSI-BLAST Tutorial]]></title>
	<description><![CDATA[<iframe width="" height="" src="https://www.youtube-nocookie.com/embed/T3kHEieyylk" frameborder="0" allowfullscreen></iframe>http:--www.biotechnology.jhu.edu-
Tutorial for PSI-BLAST, an extension of BLAST that uses matrix algebra. BLAST is a cornerstone bioinformatics tool at NCBI. BLAST is the
Basic Local Alignment Search tool and will protein and DNA sequences that
are related to a sequence that the user provides.]]></description>
	
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/14215/the-8000-years-old-tibetian-gene-mutation</guid>
	<pubDate>Wed, 20 Aug 2014 21:57:44 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/14215/the-8000-years-old-tibetian-gene-mutation</link>
	<title><![CDATA[The 8000 years old Tibetian gene mutation !!!]]></title>
	<description><![CDATA[<p>A new study has provided insight into how gene mutation around 8,000 years ago helped Tibetans' to survive in the thin air on the Tibetan Plateau, where an average elevation is of 14,800 feet.<br /><br />A study led by University of Utah scientists is the first to find a genetic cause for the adaptation, a single DNA base pair change that dates back 8,000 years and demonstrate how it contributes to the Tibetans' ability to live in low oxygen conditions.</p><p>About 8,000 years ago, the gene EGLN1 changed by a single DNA base pair. Today, a relatively short time later on the scale of human history, 88 percent of Tibetans have the genetic variation, and it was virtually absent from closely related lowland Asians. The findings indicate the genetic variation endows its carriers with an advantage.<br /><br />In those without the adaptation, low oxygen caused their blood to become thick with oxygen-carrying red blood cells, an attempt to feed starved tissues, which could cause long-term complications such as heart failure. The researchers found that the newly identified genetic variation protected Tibetans by decreasing the over-response to low oxygen.</p><p>Reference: http://www.nature.com/nature/journal/v512/n7513/abs/nature13408.html</p>]]></description>
	<dc:creator>Neel</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/44559/metagraph-ultra-scalable-framework-for-dna-search-alignment-assembly</guid>
	<pubDate>Sat, 08 Jun 2024 16:15:25 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/44559/metagraph-ultra-scalable-framework-for-dna-search-alignment-assembly</link>
	<title><![CDATA[MetaGraph: Ultra Scalable Framework for DNA Search, Alignment, Assembly]]></title>
	<description><![CDATA[<p><span>The MetaGraph framework</span><span>&nbsp;is designed to work with a wide range of input data sets, indexing from a few samples up to the contents of entire archives with hundreds of thousands of records. The indexing workflow always follows the same principle, transforming single input samples into error-removed, refined sample graphs, which are then merged into a joint metagraph index. Each input sample is annotated in the joint index as a subgraph. This graph index enriched with metadata can then be used for downstream applications such as&nbsp;</span><a href="https://metagraph.ethz.ch/#query">sequence search</a><span>&nbsp;or&nbsp;</span><a href="https://metagraph.ethz.ch/#assembly">differential assembly</a><span>.</span></p>
<p><span>Searcg link&nbsp;https://metagraph.ethz.ch/search&nbsp;</span></p>
<p><span>Pre-print&nbsp;https://www.biorxiv.org/content/10.1101/2020.10.01.322164v4&nbsp;</span></p><p>Address of the bookmark: <a href="https://metagraph.ethz.ch/" rel="nofollow">https://metagraph.ethz.ch/</a></p>]]></description>
	<dc:creator>Abhi</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/36026/mmseqs20-ultra-fast-and-sensitive-protein-search-and-clustering-suite</guid>
	<pubDate>Thu, 22 Mar 2018 10:40:51 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/36026/mmseqs20-ultra-fast-and-sensitive-protein-search-and-clustering-suite</link>
	<title><![CDATA[MMseqs2.0: ultra fast and sensitive protein search and clustering suite]]></title>
	<description><![CDATA[<p>MMseqs2 (Many-against-Many sequence searching) is a software suite to search and cluster huge protein sequence sets. MMseqs2 is open source GPL-licensed software implemented in C++ for Linux, MacOS, and (as beta version, via cygwin) Windows. The software is designed to run on multiple cores and servers and exhibits very good scalability. MMseqs2 can run 10000 times faster than BLAST. At 100 times its speed it achieves almost the same sensitivity. It can perform profile searches with the same sensitivity as PSI-BLAST at over 400 times its speed.</p>
<p>The MMseqs2 user guide is available as&nbsp;<a href="https://github.com/soedinglab/mmseqs2/wiki">Github Wiki</a>&nbsp;or as&nbsp;<a href="https://mmseqs.com/latest/userguide.pdf">PDF file</a>&nbsp;(Thanks to&nbsp;<a href="https://github.com/jgm/pandoc">pandoc</a>!)</p>
<p>Please cite:&nbsp;<a href="https://www.nature.com/nbt/journal/vaop/ncurrent/full/nbt.3988.html">Steinegger M and Soeding J. MMseqs2 enables sensitive protein sequence searching for the analysis of massive data sets. Nature Biotechnology, doi: 10.1038/nbt.3988 (2017)</a>.</p><p>Address of the bookmark: <a href="https://github.com/soedinglab/MMseqs2" rel="nofollow">https://github.com/soedinglab/MMseqs2</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/43439/mmseqs2-ultra-fast-and-sensitive-sequence-search-and-clustering-suite</guid>
	<pubDate>Wed, 06 Oct 2021 07:01:14 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/43439/mmseqs2-ultra-fast-and-sensitive-sequence-search-and-clustering-suite</link>
	<title><![CDATA[MMseqs2: ultra fast and sensitive sequence search and clustering suite]]></title>
	<description><![CDATA[<p><span>MMseqs2 (Many-against-Many sequence searching) is a software suite to search and cluster huge protein and nucleotide sequence sets. MMseqs2 is open source GPL-licensed software implemented in C++ for Linux, MacOS, and (as beta version, via cygwin) Windows. The software is designed to run on multiple cores and servers and exhibits very good scalability. MMseqs2 can run 10000 times faster than BLAST. At 100 times its speed it achieves almost the same sensitivity. It can perform profile searches with the same sensitivity as PSI-BLAST at over 400 times its speed.</span></p><p>Address of the bookmark: <a href="https://github.com/soedinglab/MMseqs2" rel="nofollow">https://github.com/soedinglab/MMseqs2</a></p>]]></description>
	<dc:creator>Abhi</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/14024/grapher</guid>
	<pubDate>Thu, 14 Aug 2014 14:02:17 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/14024/grapher</link>
	<title><![CDATA[GrapheR !!!]]></title>
	<description><![CDATA[<p>What a wonderful gem <em>GrapheR</em> is.... Oh yes it is. <em>GrapheR</em> is a GUI for base graphics in R by http://www.maximeherve.com/. The package provides a graphical user interface for creating base charts in R. It is ideal for beginners in R, as the user interface is very clear and the code is written along side into a text file, allowing users to recreate the charts directly in the console. <br /><br />Adding and changing legends? Messing around with the plotting window settings? It is much easier/quicker with this GUI than reading the help file and trying to understand the various parameters.<br />Here is a little example using the iris data set.<br /><br />library(GrapheR)<br />data(iris)<br />run.GrapheR()<br /><br />This will bring up a window that helps me to create the chart and tweak the various parameters.</p><p><img src="http://4.bp.blogspot.com/-NbnCM1dPh3E/U9aW9YxJ9oI/AAAAAAAABgo/gEPzPhOpf2Y/s1600/GrapheR.png" alt="image" width="878" height="868" style="border: 0px; border: 0px;"><br /><br />Finally, I find the underlying R code in a file created by <em>GrapheR</em>. For more details read also the <a href="http://cran.r-project.org/web/packages/GrapheR/index.html" target="_blank">package vignette</a>, which is available in <a href="http://cran.r-project.org/web/packages/GrapheR/vignettes/manual_en.pdf" target="_blank">English</a>, <a href="http://cran.r-project.org/web/packages/GrapheR/vignettes/manual_fr.pdf" target="_blank">French</a> and <a href="http://cran.r-project.org/web/packages/GrapheR/vignettes/manual_de.pdf" target="_blank">German</a>!</p>]]></description>
	<dc:creator>John Parker</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/14186/pybedtools</guid>
	<pubDate>Wed, 20 Aug 2014 01:03:41 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/14186/pybedtools</link>
	<title><![CDATA[pybedtools]]></title>
	<description><![CDATA[<p>pybedtools is a Python wrapper for Aaron Quinlan's BEDtools programs (https://github.com/arq5x/bedtools), which are widely used for genomic interval manipulation or "genome algebra". pybedtools extends BEDTools by offering feature-level manipulations from with Python. See full online documentation, including installation instructions, at http://pythonhosted.org/pybedtools/.</p><p>More at http://pythonhosted.org/pybedtools/</p><p>A powerful toolset for genome arithmetic.http://code.google.com/p/bedtools/</p>]]></description>
	<dc:creator>Shruti Paniwala</dc:creator>
</item>

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