BOL: Related items

Fools guide

Poonam Mahapatra — Sun, 02 Apr 2017 14:31:18 -0500

This website and accompaning documents are intended as a tool to help researchers dealing with non-model organisms acquire and process transcriptomic high-throughput sequencing data without having to learn extensive bioinformatics skills. It covers all steps from tissue collection, sample preparation and computer setup, through addressing biological questions with gene expression and SNP data.

http://sfg.stanford.edu/denovo.html

http://sfg.stanford.edu/sequencing.html

http://sfg.stanford.edu/BLAST.html

http://sfg.stanford.edu/denovo.html

Address of the bookmark: http://sfg.stanford.edu/guide.html

IBL laboratory

Mon, 12 Aug 2013 02:02:29 -0500

The IBL laboratory focuses on the multi-disciplinary analyses of the global responses of model microorganisms, cyanobacteria (mainly Synechocystis PCC6803) and yeasts (mainly Saccharomyces cerevisae) to environmental stresses triggered by oxidative agents, heavy metals, or drastic changes in nutrients availability. The genome-wide responses studied with the "omics" techniques (transcriptomics, proteomics, metabolomics and genetics) generate a wealth of experimental data, which are processed, archived, integrated and represented as working models through bioinformatics and mathematics.

Link : http://www-dsv.cea.fr/en/instituts/institut-de-biologie-et-de-technologies-de-saclay-ibitec-s/unites-de-recherche/service-de-biologie-integrative-et-genetique-moleculaire-sbigem/laboratoire-de-biologie-integrative-lbi/presentation__1

Mapping NGS

Abhimanyu Singh — Tue, 02 May 2017 07:58:07 -0500

NGS data are just a bunch of sequences, you have no idea which region in the genome each sequences comes from, which gene it represents...
To know that you have to align the sequences to the reference sequence. The reference sequence is in most cases the full genome sequence but sometimes, a library of EST sequences is used.
In either way, aligning your sequence reads to the reference sequence is called mapping.

The most used mappers of DNA-seq data are BWA and Bowtie for DNA-Seq data and Tophat, STAR or HISAT for RNA-Seq data. Mappers differ in which options they can take in, how fast and how accurate they are. Bowtie is faster than BWA, but looses some sensitivity (does not map an equal amount of reads to the correct position in the genome).

Address of the bookmark: http://wiki.bits.vib.be/index.php/Mapping_of_NGS_data

Computational Proteomics : Lets remember the basics

Jitendra Narayan — Thu, 01 Aug 2013 17:24:20 -0500

I spend some of my valuable time in computational drug designing sector. I remember my initial proteomics days, playing with interactive protein visualization software and dreaming big. Fortunately or unfortunately, I switched to genomics and handling the genomic floods in Petabytes which is expected to be in Brontobytes in coming years. Did I mention Brontobytes ??? Let me call to my server personnel … it gonna tsunami !!!!!

Today, refreshing my old memories I decided to blog about the basic knowledge of biochemistry and computational proteomics skills, but after I found several article on internet saying exactly what I had wanted to say I thought I might as well just redirect BOL's blog readers there instead:

Here is the list of website and videos links which provide a good resource for you basic chemistry need:

http://tecreativ.blogspot.co.uk/2012/09/funny-shortcut-remember-periodic-table.html

This blog have some specific hindi word to remember entire periodic table. I really like

Group 14 (C Si Ge Sn Pb) -> Sentence “Chemistry Sir Gives Sanki Problems”

Sanki is a hindi word which mean crazy :P

I found this link useful as well http://www.wikihow.com/Memorise-the-Periodic-Table

The eagle genomics group provide an element of bioinformatics in periodic tables. Yes you got it, this is not periodic table rather bioinformatics tools with periodicals

http://elements.eaglegenomics.com/

You can also try this video links, which provide you an overview with tricks on periodic tables:

http://www.youtube.com/watch?v=fLSfgNxoVGk

http://www.youtube.com/user/periodicvideos

For drug design educational material, software, tools, databses, viewer, file format and many more stuff at one place http://www.allfordrugs.com/drug-design/ I highly recommend you all computational drug designer to bookmark this page for future studies as well.

I just remember one of my mini project in which I use my flash knowledge (flash .. oh ya flash) to explain amino acids in interactive and user friendly manner. I can’t provide It right now, but promise you to provide a link in near future. I hope that you will enjoy my flashy creative skills :).

Moreover, I found some of very interesting tricks to remember all amino acids chemical formulae on youtube at

http://www.youtube.com/watch?v=gqrWb0fmzQ&list=PL6132651E70BB5575

http://www.youtube.com/watch?v=C2GfoGXfySQ&list=PL6132651E70BB5575

Key points for computer added drug designers?
1. A shortage of biochemistry skills means that you absolutely nowhere in understanding the key concept and do research.
2. Keep handy with complex mathematical formula, before merely running tools or software.
3. Dig it better and deeper guys .. design it.

Salzberg lab

Mon, 15 May 2017 05:14:01 -0500

We are a computational biology lab that develops novel methods for analysis of DNA and RNA sequences. Our research includes software for aligning and assembling RNA-seq data, whole-genome assembly, and microbiome analysis. We work closely with biomedical scientists to apply these methods to current problems arising in a broad spectrum of biological and medical research areas. We’re also part of the Center for Computational Biology, a group of 20+ faculty members and their labs at Johns Hopkins working on computational, statistical, and mathematical methods that can turn massive genomic data sets into biologically and clinically useful information.

https://salzberg-lab.org/

IMTECH Lab

Sun, 15 Sep 2013 09:41:04 -0500

Computer Aided Protein Structure Prediction; Identification of Vaccine
Candidates (T-Epitope prediction); Analysis of Nucleotide/Protein Sequences; Development of Web Server/

Software; Creation of Public Domain Resources in Biology
Present Status::

Developing prediction methods for gene, beta-turn, secondary structure and MHC-binding sites.
Area of Interest ::

Comparison of force field simulations. Analysis of DNA-protein interactions using molecular mechanics methods.Drug Target Identification using in silico biology.

More @ http://www.imtech.res.in/bic/index.php?option=com_content&view=article&id=65

PIs: http://www.imtech.res.in/bic/index.php?option=com_content&view=article&id=69

3rd Annual Next Generation Sequencing Asia Congress 2013 at Singapore, Singapore

Wed, 14 Aug 2013 09:55:04 -0500

The 3rd Annual Next Generation Sequencing Asia Congress is to be held on the 22nd and 23rd of October 2013 in Singapore. Over the 2 days, the conference will provide an overview of the current options of next-generation sequencing platforms, technologies, applications and the newest computational tools for the analysis of next-generation sequencing data and analytical genomics as well as overcoming data management problems. The event will attract over 200 senior-level decision makers working in areas such as next generation sequencing, analytical genomics, computational biology, oncology, RNA profiling, molecular genomics, biomarkers, bioinformatics & data management and clinical & diagnostics development.

Dated : 22 Nov 2013 -23 Nov 2013

http://www.ngsasia-congress.com/

Taverna Workflow Management System

Madhvan Reddy — Thu, 15 Aug 2013 19:34:32 -0500

Taverna is an open source domain independent Workflow Management System – a suite of tools used to design and execute scientific workflows. Taverna has been created by the myGrid project and is funded through a range of organisations and projects.

The Taverna suite is written in Java and includes the Taverna Engine(used for enacting workflows) that powers both the Taverna Workbench(the desktop client application) and the Taverna Server (which allows remote execution of workflows). Taverna is also available as a Command Line Tool for a quick execution of workflows from a terminal.

Address of the bookmark: http://www.taverna.org.uk/

Bioinformatics Infrastructure Facility (BIF), Gargi College, University of Delhi @ Traineeship

Mon, 19 Aug 2013 18:43:03 -0500

Gargi College was established in the year 1967 and is a leading South Campus college of the University of Delhi. It is a college for women and offers education in Arts and Humanities, Commerce, Science and Education.

Gargi believes in its mission statement that every student who passes through the portals of the college emerges as a wholly developed individual symbolizing the spirit of enterprise and inquiry that characterizes Gargi.

Bioinformatics Infrastructure Facility (BIF), Gargi College, University of Delhi invites candidates for filling up the following purely temporary positions sponsored by DBT, New Delhi.

1. Name of the post: Traineeship
Essential Qualification: Post Graduate degree in Bioinformatics or any other branch of Life Sciences preferably with dissertation in Bioinformatics.
Desirable Qualification: Prior knowledge of programming languages such as C, VB, SQL etc. and software/database development.

2. Name of the post: Research Associate
Essential Qualification: PhD in Bioinformatics/Biological Sciences/Computer Science or allied sciences with proven experience in bioinformatics.

3. Name of the post: Studentship
Essential Qualifications: Final year Post Graduate students pursuing a degree in Bioinformatics or any branch of Life Science with knowledge of bioinformatics.

How to apply:
Interested candidates are required to appear for the walk in interview on 29th Aug, 2013 at 10.00 AM in Principal’s Office, Gargi College, Sirifort Road, N. Delhi-110049, with their CVs, original documents and a set of Photostat copies of all original documents.

http://www.du.ac.in/fileadmin/DU/students/Pdf/du/advt/2013/16082013_Gargi_RAplus2_Advt.pdf

CSIR-INSTITUTE OF GENOMICS & INTEGRATIVE BIOLOGY

Thu, 29 Aug 2013 05:22:03 -0500

CSIR-INSTITUTE OF GENOMICS & INTEGRATIVE BIOLOGY, Mall Road, Delhi 110007

POSITIONS OPEN FOR TEMPORARY RESEARCH PROJECT POSTS

(Date of interview 23rd September 2013 at 10:30 AM)

CSIR-Institute of Genomics & Integrative Biology (IGIB), desires to engage qualified incumbents on purely temporary basis as detailed below:

Project Code/Title (Project Code BSC0123)

Genome dynamics in Cellular Organization, Differentiation and Enantiostasis (GENCODE)

Project Fellow

First Class M.Sc./M.Tech in bioinformatics/Human Genetics/Genomics

Rs. 16,000/- + 30 % HRA per month

Sr. Project Fellow

First Class M.Sc./M.Tech in bioinformatics/Human Genetics/Genomics

With two years of experience in NGS data analysis.

Rs. 18,000/- + 30 % HRA per month

Age relaxation as per Govt. of India instructions.

Engagement is for the project and on behalf of the funding agency and the tenure shall be as mentioned above. The duration of the post is initially for One year or till the closing date of the project, whichever is earlier. Tenure may be extendable up to project duration. Contract may be terminated at any time by giving one-month notice by either side. The applicants will have no claim implicit or explicit for consideration against any CSIR/IGIB post.

How to Apply:

It is mandatory for eligible applicants to apply by both the processes as given below:

1. Sending the resume in MS Word format directly to hrd@igib.res.in (Mentioning the Project Code-Post Code in the Subject Line of the email example:GAP0059-1)

2. They also need to fill up proforma by clicking on the following link HR Online Form.

3. Candidate cannot apply for more than two posts.

Last date of receiving application is 02-09-2013.

No application would be entertained with result awaited status or after due date.

The email will be sent to the short listed candidates.

No TA/DA will be paid to the candidates to attend the interview. The engagement shall be as per guidelines of CSIR/Funding agency. Candidates will have an option to give reply in Hindi.

Note: The shortlisted candidates, who will receive the email for interview, have to report at 09:00 AM on the day of interview along with any Photo ID card and original certificates for entry purpose. Entry will be closed by 10:00 AM.

More @ http://www.igib.res.in/sites/default/files/23092013.htm