BOL: Related items

Scientist B at AIIMS, New Delhi, Delhi

Thu, 03 Sep 2020 07:04:11 -0500

Scientist B at AIIMS, New Delhi, Delhi

Overview
Applications are invited from eligible candidates for the following position under Meity funded research project entitled: Artifical Intelligence in Oncology, Harnsessing big data and advanced computing to provide personalized diganosis and treatment for cancer patients purely on contractual basis

Scientist B

Salary: Rs.80,000/-

Qualification: 1st Class Masters Degree in Bioinformatics/ Computer Science/ Statistics with Ph.D in relevant subject from a recognized University with experience in Machine learning/ AI project plus two years research experience

Age: Upto 40 years

Details
Experience:2 Years
Location:New Delhi
Education:1st Class Masters Degree
SALARY: Rs.80,000/-
Key Skills: Research Fellowship
Desired Profile
Two years research experience

Company: AIIMS
All India Institute of Medical Sciences, New Delhi is a medical school, hospital and public medical research university

More at https://www.aiims.edu/en/notices/recruitment/aiims-recruitment.html?id=10844
PDF https://www.aiims.edu/images/pdf/recruitment/advertisement/Post_BioChem_22_08_20.PDF

Doctoral researcher (PhD) in Computational Biology / Biostatistics at Luxembourg Centre for Systems Biomedicine (LCSB)

Sun, 25 Oct 2020 22:59:54 -0500

Contract Type: Fixed Term Contract
Work Hours: Full Time 40.0 Hours per Week
Location: Belval
Student and employee status (36 months studies programme, as per university standards) with project funding available for up to 48 months
36 months fixed-term contract (renewable depending on thesis progress evaluation)
Job Reference: UOL03604
Further Information
Applications should be submitted online and include:

A detailed Curriculum vitae
A motivation letter, including a brief description of past research experience and future interests, as well as the earliest possible starting date
Copies of degree certificates and transcripts
Name and contact details of at least two referees
Early application is highly encouraged, as the applications will be processed upon reception. Please apply ONLINE formally through the HR system. Applications by email will not be considered.

*gn=gender neutral.

More at https://recruitment.uni.lu/en/details.html?id=QMUFK026203F3VBQB7V7VV4S8&nPostingID=54876&nPostingTargetID=74639&mask=karriereseiten&lg=UK

ProteoClade: A taxonomic toolkit for multi-species and metaproteomic analysis

Jit — Wed, 18 Mar 2020 14:27:20 -0500

ProteoClade is a Python library for taxonomic-based annotation and quantification of bottom-up proteomics data. It is designed to be user-friendly, and has been optimized for speed and storage requirements.

ProteoClade helps you analyze two general categories of experiments:

Targeted Database Searches: Experiments in which a limited number of species are defined ahead of time, such as those involving Patient-Derived Xenografts (PDXs) or host-pathogen interactions. Reference protein sequence databases are used for targeted searches (ex: using Mascot, MaxQuant).
De Novo Searches: Experiments in which the organisms are unspecified ahead of time or involve samples of high taxonomic complexity. Mass spectra are analyzed in the absence of a reference database (ex: using PEAKS, PepNovo).

ProteoClade scales from two organisms to every organism in UniProt. Please refer to the complete documentation at proteoclade.readthedocs.io for installation, a user's guide, and examples.

https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1007741

Address of the bookmark: https://github.com/HeldLab/ProteoClade

Two postdoc positions to study multiscale genome evolution and cephalopod gene regulation (University of Vienna, Austria)

Thu, 17 Dec 2020 11:45:16 -0600

Vienna Biocenter are seeking two postdoctoral researchers to join our team and work on the ERC funded project "METASCALE: Modes of genome evolution during major metazoan transitions". The task of both positions will be to study co-evolutionary trends within animal genomes and their association with the emergence of new gene regulation. Our group employs methods of comparative and regulatory genomics to study the regulatory impact of transitions in animal genome architecture. More recently, we have identified a major genome reorganization in the "smart" coleoid cephalopod molluscs (squid, octopus, cuttlefish) that, together with other genomic changes, potentially comprises a unique path or mode of genome evolution among animals. We are thus interested in quantifying these modes of genome evolution across all available animal genomes and to test whether their shifts are associated with the emergence of novel regulation (e.g., in cephalopods). One of our main model species is the Hawaiian bobtail squid species Euprymna scolopes. The tasks of the two candidates will be complimentary and highly collaborative with one position focusing on comparative genomics analyses across all metazoans and the other position on regulatory genomics in the squid. A solid background in in bioinformatics and comparative genomics is highly desired for the first position, whereas the second position will benefit from experience in molecular and regulatory genomics methods such as HiC, ATAC-seq, RNA-seq or single cell transcriptomics.

The postdocs will join an international group and network of researchers at the University of Vienna studying a diverse range of species and questions in molecular evolution, development, morphology and genomics. Our group is also part of the large evolVienna network of more than 50 evolutionary biology labs in Vienna, across several universities and research institutes. Our Faculty will be relocating to a new campus at the Vienna Biocenter in summer 2021 (https://biologiezentrum.univie.ac.at/en/). Vienna is a vibrant historic European capital with a high QOL. Information about postdoctoral salaries in Austria can be found on this webpage: https://www.fwf.ac.at/en/research-funding/personnel-costs/

Earliest start date will be after July 2021. Initial term of employment is for two years with the possibility of extension. Remote working, at least initially, is a possibility.

Requirements:
- PhD degree or equivalent by the start date
- Publishing record in peer-reviewed journals or evidence thereof
- At least 2 letters of support

Applications including a letter of motivation should be submitted via the Job Center to the University of Vienna (https://personalwesen.univie.ac.at/en/jobs-recruiting/job-center/,
job reference number 11615).

Application deadline: January 15th 2021.
Application link: https://univis.univie.ac.at/ebewerbung

Bioinformatics in Africa:- Part 1

BioStar — Sun, 31 Jan 2021 09:04:01 -0600

The Institut Pasteur de Côte d’Ivoire was created by the N°72511 law of July 27th, 1972 under the Presidency of his Excellency Felix Houphouët Boigny and Professor Jacques Monod, then Leading of the Pasteur institute of Paris.

The objectives of the Bioinformatics pole are:

• Encourage the access to innovations in research and the best exploitation of research data management.

• Develop the critical spirit of the researchers around their axis of research.

• Bring an active help to the improvement of the public health while having for constant worries to feed it by research and the innovation.

• Start training researchers to use bioinformatics as an indispensable tool to research.

• Encourage interdisciplinary creating a network of scientific information available to the researchers of the institute and partners

Longterm training activities:

• To integrate the bioinformatics in the training programs of academic scientists.

• Development of West Africa Centre training in bioinformatics and genome data analysis.

Shortterm training activities:

The IPCI will organize in the month of May 2007 a yearly regional course of initiation and using genome data analysis with the participation of the Centre Biotechnologique de Sfax, Tunisia (Pr Ahmed Rebaï, Department of bioinformatics).

More at https://www.pasteur.ci/

RNA-seq workflow: gene-level exploratory analysis and differential expression

Jit — Sat, 09 Oct 2021 07:59:23 -0500

Here we walk through an end-to-end gene-level RNA-seq differential expression workflow using Bioconductor packages. We will start from the FASTQ files, show how these were quantified to the reference transcripts, and prepare gene-level count datasets for downstream analysis. We will perform exploratory data analysis (EDA) for quality assessment and to explore the relationship between samples, perform differential gene expression analysis, and visually explore the results.

Address of the bookmark: http://master.bioconductor.org/packages/release/workflows/vignettes/rnaseqGene/inst/doc/rnaseqGene.html

Bioinformatics in Africa: Part5 - Nigeria

BioStar — Sat, 06 Feb 2021 21:13:47 -0600

Covenant University (CU)Ota:
Covenant University (with her enriching and growing stateoftheart laboratories in the area of science and technology, arts, business and social sciences) is presently the Best University in Nigeria (Private University category), based on the recent overall rating just concluded by the Nigeria University Commission (NUC). Recently, Covenant University has initiated the establishment of a Centre for Applied Biotech, BioInformatics and Microbiology (CBBM) to be situated at the University. The institute has been designed to be a PublicPrivate Partnership for a productive synergy b/w Academia, Industry and Government. The whole concept is still evolving and more details will be release soon. As regards CBBM, a dedicated computing lab is in plan, but even our computing capacity is presently enormous. In the department of Computer and Information Sciences, we have more than 250 Pentium 4 PCs set aside for teaching and research purposes. Furthermore, we have several moderate speed PCs at the Postgraduate research lab and our engineering departments and units. Our wet lab facilities is presently minimal (basic for teaching), the Centre requirement as it touches the wetlaboratories is also set to upgrade this to basic tools expected at an international centre of learning.

University of Ibadan (UIB)Ibadan:
There has been significant increase in the number of bioinformatics activities in Nigeria (and West Africa) since 2003 when the program was initiated by the West African Biotechnology Workshops Series (WABWS, http://www.wabw.org) at the University of Ibadan, Nigeria (in collaboration with the South African National Bioinformatics Institute (SANBI, http:/www.sanbi.ac.za). Workshops that were open to scientists from all African countries have seen a very high number of applications from scientists based in West Africa. The encouraging desire to acquire cuttingedge skills to computational process data and extract useful knowledge from genome projects led to the interest of the West African Biotechnology Workshops (WABW) to develop an agenda to address the bioinformatics skills gap among scientists in West Africa. An increased commitment from agencies like NEPAD would be required in the provision of infrastructure to establish and sustain regional and national networks.

University of Ilorin (UIL)Ilorin:
The University of Ilorin was established in 1976 by the Federal Government of Nigeria. Bioinformatics activities started at the University in February 2003 with the establishment of the West African Bioinformatics Research Initiative (WABRI). However, progress has been rather slow due to inadequate funding. We are mainly engaged in Bioinformatics training at the introductory level and proteomics studies on various species of malaria parasites. Recently, we became interested in comparative genome analysis of various species of Plasmodium and the comparison of chloroquine sensitive and chloroquine resistant strains of Plasmodium falciparum. Other activities and areas of interest can be seen on our website, http://www.wabri.org, although not all our proposed interests have been fully implemented due to our level of funding.

Training:
The University of Ilorin has introduced M.Sc. and Ph.D. programmes in Computer Science (with options in Bioinformatics). The programme is based in the Department of Computer Science and emphasis is on the development of algorithms to solve problems in bioinformatics. The Covenant University offers M.Sc. and Ph.D in Computer Science with option in Bioinformatics (Computational Biology). Furthermore, through affiliated departments, the CBBM is been design to award Diploma and Degree certificates in Biotechnology.

Web sites and links: http://www.covenantuniversity.com http://www.run.edu.ng http://www.uniben.edu http://www.wabri.org http://www.wabw.org http://www.unilorin.edu.ng http://www.wabri.org http://www.asopah.org

Tools for Differential expression analysis

Abhi — Tue, 08 Nov 2022 03:40:33 -0600

apeglm - https://bioconductor.org/packages/release/bioc/html/apeglm.html

ashr - https://github.com/stephens999/ashr, https://cran.r-project.org/web/packages/ashr/index.html

consensusDE - https://bioconductor.org/packages/release/bioc/html/consensusDE.html

DESeq2 - https://bioconductor.org/packages/release/bioc/html/DESeq2.html

edgeR - https://bioconductor.org/packages/release/bioc/html/edgeR.html

limma - https://kasperdanielhansen.github.io/genbioconductor/html/limma.html https://bioconductor.org/packages/release/bioc/html/limma.html

MetaCycle - https://cran.r-project.org/web/packages/MetaCycle/index.html, https://github.com/gangwug/MetaCycle

RUVSeq - https://bioconductor.org/packages/release/bioc/html/RUVSeq.html

SARTools - https://github.com/PF2-pasteur-fr/SARTools

tximport - https://github.com/mikelove/tximport

RA Bioinformatics at Sir Ganga Ram Hospital, New Delhi

Sun, 14 Mar 2021 10:40:18 -0500

Opportunities available at Institute of Medical Genetics & Genomics, Sir Ganga Ram Hospital, New Delhi.

1) Senior Research Fellow under ICMR Project: M.Sc. (Life Sciences) with 2 years of experience (preferable in the field of Bioinformatics) or MBBS Degree.

2) Research Associate under ICMR Project: . Ph.D.(Life Science/Biotechnology/Bioinformatics) or equivalent degree or having 3 years of research, teaching and design and development experience after M.Tech with at least one research paper in science Citation Indexed (SCI) Journal.
Work experience in the area of Human genomics/Next Generation Sequencing data analysis/Big data genomics would be preferred.
Application link:

https://sgrh.com/joblist

Post Code: 2023, 2024

Bactopia: a flexible pipeline for complete analysis of bacterial genomes

Abhi — Sat, 08 Jun 2024 16:25:08 -0500

Bactopia is a flexible pipeline for complete analysis of bacterial genomes. The goal of Bactopia is process your data with a broad set of tools, so that you can get to the fun part of analyses quicker!

Bactopia was inspired by Staphopia, a workflow we (Tim Read and myself) released that is targeted towards Staphylococcus aureus genomes. Using what we learned from Staphopia and user feedback, Bactopia was developed from scratch with usability, portability, and speed in mind from the start.

Bactopia uses Nextflow to manage the workflow, allowing for support of many types of environments (e.g. cluster or cloud). Bactopia allows for the usage of many public datasets as well as your own datasets to further enhance the analysis of your sequencing. Bactopia only uses software packages available from Bioconda and Conda-Forge to make installation as simple as possible for all users.

To highlight the use of Bactopia and Bactopia Tools, we performed an analysis of 1,664 public Lactobacillus genomes, focusing on Lactobacillus crispatus, a species that is a common part of the human vaginal microbiome. The results from this analysis are published in mSystems under the title: Bactopia: a flexible pipeline for complete analysis of bacterial genomes

Address of the bookmark: https://bactopia.github.io/latest/