Then I thaught it migh be a problem of graphical display and I opened the terminal out of curiosity, and I found out that there is no ~/Desktop folder at all. What happened? What do I need to do?

Then I google the problem and found this is a very common problem after updates. To fix this problem, follow these steps:

You need to edit the ~/.config/user-dirs.dirs file, and make sure the contents of the file are like the following:

XDG_DESKTOP_DIR="$HOME/Desktop"
XDG_DOWNLOAD_DIR="$HOME/Downloads"
XDG_TEMPLATES_DIR="$HOME/"
XDG_PUBLICSHARE_DIR="$HOME/Share"
XDG_DOCUMENTS_DIR="$HOME/Documents"
XDG_MUSIC_DIR="$HOME/Music"
XDG_PICTURES_DIR="$HOME/Pictures"
XDG_VIDEOS_DIR="$HOME/Videos"

Then restart nautilus:

killall nautilus

or

nautilus -q

Then, open nautilus via Unity menu (press the Super key) or using the run command (Alt+F2)

unzip blatSrc35.zip

to unpack the archive. This gives a directory blatSrc now move into that directory.

#cd blatSrc

before you begin read the README file that comes with the source code.

One thing about building blat is that you need to set the MACHTYPE variable so that the BLAT sources know what type of machine you are compiling the software on.

on most *nix machines, typing

echo $MACHTYPE

will return the machine architecture type.

On my CentOS 6 based system this gave:

x86_64-redhat-linux-gnu

However, what BLAT requires is the 'short value' (ie the first part of the MACHTYPE). To correct this, in the bash shell type (change this to the correct MACHTYPE for your system)

MACHTYPE=x86_64
export MACHTYPE

now running the command:

echo $MACHTYPE

should give the correct short form of the MACHTYPE:

x86_64

now create the directory lib/$MACHTYPE in the source tree. ie:

mkdir lib/$MACHTYPE

For my machine, lib/x86_64 already existed, so I did not have to do this, but this is not the case for all architectures.

The BLAT code assumes that you are compiling BLAT as a non-privileged (ie non-root) user. As a result, you must create the directory for the executables to go into:

mkdir ~/bin/$MACHTYPE

If you are installing as a normal user, edit your .bashrc to add the following (change the x86_64 to be your MACHTYPE):

export PATH=~/bin/x86_64::$PATH

For me, though, this was not good enough. I wanted the executables in /usr/local/bin where all my other code goes. As a result I did some hackery...

There is a master make template in the inc directory called common.mk and I edited this file with the command:

vi inc/common.mk

I replaced the line

    BINDIR=${HOME}/bin/${MACHTYPE}

with

    BINDIR=/usr/local/bin

saved and quit (as this is in my path, I do not need to do anything else)

All the preparation is now done and you can create the blat executables by going into the toplevel of the blat source tree (for me it was /usr/local/src/blat/blatSrc, but change to wherever you unpacked blat into).

Now simply run the command:

make

to compile the code.

Blat installed cleanly and the executables were all neatly placed in /usr/local/bin/x86_64, just like I wanted.

now simply running the command:

blat

on the command line gives me information on blat and sample usage.

Blat is installed and it's installed properly in my system code tree!!!

In this tutorial, we will show you how to install and configure Elgg social networking platform on Ubuntu 20.04.

Prerequisites

• A fresh Ubuntu 20.04 VPS on the Atlantic.net Cloud Platform
• A valid domain name pointed to your server IP
• A root password configured on your server

Step 1 – Create Atlantic.Net Cloud Server

First, log in to your Atlantic.Net Cloud Server. Create a new server, choosing Ubuntu 20.04 as the operating system with at least 2GB RAM. Connect to your Cloud Server via SSH and log in using the credentials highlighted at the top of the page.

Once you are logged in to your Ubuntu 20.04 server, run the following command to update your base system with the latest available packages.

apt-get update -y

Step 2 – Install Apache, MariaDB and PHP

Elgg runs on Apache web server, is written in PHP, and uses MySQL/MariaDB as a database backend, so you will need to install the Apache, MariaDB, PHP and other required PHP extensions to your server. You can install all of them with the following command:

apt-get install apache2 mariadb-server php libapache2-mod-php php-common php-sqlite3 php-curl 
php-intl php-mbstring php-xmlrpc php-mysql php-gd php-xml php-cli php-zip unzip wget -y

After installing all the packages, edit the php.ini file and change some recommended settings.

nano /etc/php/7.4/apache2/php.ini

Change the following values:

max_execution_time = 300
memory_limit = 512M
upload_max_filesize = 100M
date.timezone = Asia/Kolkata

Save and close the file, then restart the Apache service to apply the configuration changes.

systemctl restart apache2

Step 3 – Create a Database for Elgg

Next, you will need to create a database and user for Elgg. First, log in to MySQL shell with the following command:

mysql

Once logged in, create a database and user with the following command:

CREATE DATABASE elgg;
CREATE USER 'elgg'@'localhost' IDENTIFIED BY 'secure-password';

Next, grant all the privileges to the elgg database with the following command:

GRANT ALL ON elgg.* TO 'elgg'@'localhost' IDENTIFIED BY 'secure-password' WITH GRANT 
OPTION;

Next, flush the privileges and exit from the MariaDB shell with the following command:

FLUSH PRIVILEGES;
EXIT;

At this point, the MariaDB database is created for Elgg.

Step 4 – Install Elgg

First, download the latest version of Elgg from its official website using the following command:

wget https://elgg.org/download/elgg-3.3.13.zip

Once the download is completed, unzip the downloaded file with the following command:

unzip elgg-3.3.13.zip

Next, move the extracted directory to the Apache root directory:

mv elgg-3.3.13 /var/www/html/elgg

Next, create a data directory and set proper ownership and permissions to the Elgg directory:

mkdir /var/www/html/data
chown -R www-data:www-data /var/www/html/elgg
chown -R www-data:www-data /var/www/html/data
chmod -R 755 /var/www/html/elgg

Once you are finished, you can proceed to the next step.

Step 5 – Configure Apache for Elgg

Next, you will need to configure Apache to serve Elgg. You can configure it by creating a new Apache virtual host configuration file:

nano /etc/apache2/sites-available/elgg.conf

Add the following lines:

<VirtualHost *:80>
ServerAdmin admin@example.com
DocumentRoot /var/www/html/elgg/
ServerName elgg.example.com
Options FollowSymLinks
AllowOverride All
ErrorLog /var/log/apache2/elgg-error_log
CustomLog /var/log/apache2/elgg-access_log common
</VirtualHost>

Save and close the file, then enable the virtual host and Apache rewrite module with the following command:

a2ensite elgg.conf
a2enmod rewrite

Finally, restart the Apache service to apply the changes:

systemctl restart apache2

Step 6 – Access Elgg Web Interface

Now, open your web browser and access the Elgg web interface using the URL http://elgg.example.com. You should see the Elgg welcome screen:

http://biopython.org/DIST/docs/tutorial/Tutorial.html

Orange Bioinformatics provides access to publicly available data, like GEO data sets, Biomart, GO, KEGG, Atlas, ArrayExpress, and PIPAx database. As for the analytics, there is gene selection, quality control, scoring distances between experiments with multiple factors. All features can be combined with powerful visualization, network exploration and data mining techniques from the Orange data mining framework.

Address of the bookmark: https://pypi.python.org/pypi/Orange-Bioinformatics/2.5.34

Simple and efficient tools for data mining and data analysis
Accessible to everybody, and reusable in various contexts
Built on NumPy, SciPy, and matplotlib
Open source, commercially usable - BSD license

More at http://scikit-learn.org/stable/index.html

Address of the bookmark: http://scikit-learn.org/stable/auto_examples/index.html

Professionally, Python is great for backend web development, data analysis, artificial intelligence, and scientific computing. Many developers have also used Python to build productivity tools, games, and desktop apps, so there are plenty of resources to help you learn how to do those as well.

For pros and cons visit http://www.bestprogramminglanguagefor.me/why-learn-python and http://bioinformaticsonline.com/discussion/view/459/python-vs-perl

More resources at https://github.com/CodementorIO/Python-Learning-Resources

Following are the list of useful python programming resources:

• 20 Python Libraries You Aren't Using (But Should) (Just fill the fields with any values)
• A Beginner's Python Tutorial
• A Byte of Python (3.x) (HTML, PDF, EPUB, Mobi)
• A Guide to Python's Magic Methods - Rafe Kettler
• A Whirlwind Tour of Python - Jake VanderPlas (PDF) (EPUB, MOBI)
• Automate the Boring Stuff - Al Sweigart
• Biopython (PDF)
• Build applications in Python the antitextbook (3.x) (HTML, PDF, EPUB, Mobi)
• Building Machine Learning Systems with Python - Willi Richert & Luis Pedro Coelho, Packt. (Just fill the fields with any values)
• Building Skills in Object-Oriented Design (Python) (PDF) (2.1.1)
• Building Skills in Python (PDF) (2.6)
• Code Like a Pythonista: Idiomatic Python
• CodeCademy Python
• Composing Programs (3.x)
• Data Structures and Algorithms in Python - B. R. Preiss (PDF)
• Dive into Python 3 - Mark Pilgrim (3.0)
  • Dive into Python - Mark Pilgrim (2.3)
• From Python to NumPy
• Full Stack Python
• Functional Programming in Python (Just fill the fields with any values)
• Fundamentals of Python Programming - Richard L. Halterman (PDF) (3.2)
• Google's Python Class (2.4 - 2.x)
• Google's Python Style Guide
• Hacking Secret Cyphers with Python - Al Sweigart (3.3)
• Hadoop with Python (Just fill the fields with any values)
• High Performance Python (PDF)
• Hitchhiker's Guide to Python! (2.6)
• How to Make Mistakes in Python - Mike Pirnat (PDF) (1st edition)
• How to Think Like a Computer Scientist: Learning with Python, Interactive Edition (3.2)
  • How to Think Like a Computer Scientist: Learning with Python - Allen B. Downey, Jeff Elkner and Chris Meyers (2.4)
  • Think Python - Allen B. Downey (2.x & 3.0)
• Intermediate Python - Muhammad Yasoob Ullah Khalid (1st edition)
• Introduction to Programming with Python (3.3)
  • Introduction to Programming Using Python - Cody Jackson (1st edition) (2.3)
• Introduction to Python - Kracekumar (2.7.3)
• Invent Your Own Computer Games With Python - Al Sweigart (3.1)
• Learn Python, Break Python
• Learn Python in Y minutes
• Learn Python The Hard Way (2.5 - 2.6)
• Learn to Program Using Python - Cody Jackson (PDF)
• Learning Python - Fabrizio Romano, Packt. (Just fill the fields with any values)
• Learning to Program
• Lectures on scientific computing with python - J.R. Johansson (2.7)
• Making Games with Python & Pygame - Al Sweigart (2.7)
• Modeling Creativity: Case Studies in Python - Tom D. De Smedt (PDF)
• Natural Language Processing with Python (3.x)
• Non-Programmer's Tutorial for Python 3 (3.3)
  • Non-Programmer's Tutorial for Python 2.6 (2.6)
• Picking a Python Version: A Manifesto (Just fill the fields with any values)
• Porting to Python 3: An In-Depth Guide (2.6 - 2.x & 3.1 - 3.x)
• Practical Programming in Python - Jeffrey Elkner (PDF)
• Problem Solving with Algorithms and Data Structures using Python - Bradley N. Miller and David L. Ranum
• Program Arcade Games With Python And Pygame (3.3)
• Programming Computer Vision with Python (PDF)
• Python 2 Official Documentation (PDF, HTML, TEXT) (2.x)
• Python 2.7 quick reference - New Mexico Tech (2.7)
• Python 3 Official Documentation (PDF, EPUB, HTML, TEXT) (3.x)
• Python Cookbook - David Beazley
• Python Data Science Handbook - Jake VanderPlas (HTML, Jupyter Notebooks)
• Python for Econometrics - Kevin Sheppard (PDF) (2.7.5)
• Python for Everybody Exploring Data Using Python 3 - Charles Severance (PDF, EPUB, HTML)
  • Python for Informatics: Exploring Information (2.7.5)
• Python for you and me (2.7.3)
• Python for you and me (3.x)
• Python Idioms (PDF)
• Python in Education (Just fill the fields with any values)
• Python in Hydrology - Sat Kumar Tomer
• Python Koans (2.7 or 3.x)
• Python Module of the Week (3.x)
  • Python Module of the Week (2.x)
• Python Notes for Professionals - Compiled from StackOverflow documentation (3.x)
• Python Practice Book (2.7.1)
• Python Practice Projects
• Python Programming (PDF) (2.6)
• Scipy Lecture Notes
• SICP in Python (3.2)
• Snake Wrangling For Kids (3.x)
• Suporting Python 3: An In-Depth Guide (2.6 - 2.x & 3.1 - 3.x)
• Test-Driven Web Development with Python (3.3 - 3.x)
• Text Processing in Python - David Mertz (2.3 - 2.x)
• The Coder's Apprentice: Learning Programming with Python 3 - Pieter Spronck (PDF) (3.x)
• The Definitive Guide to Jython, Python for the Java Platform - Josh Juneau, Jim Baker, Victor Ng, Leo Soto, Frank Wierzbicki (2.5)
• The Little Book of Python Anti-Patterns (Source)
• The Programming Historian - William J. Turkel, Adam Crymble and Alan MacEachern
• The Python Ecosystem: An Introduction
• The Python GTK+ 3 Tutorial
• The Standard Python Library - Fredrik Lundh
• Think Complexity - Allen B. Downey (2nd Edition) (PDF, HTML)
• Web2py: Complete Reference Manual, 6th Edition (pre-release) (2.5 - 2.x)
• Wikibooks: Python Programming (2.7)

Other tools

https://github.com/shenwei356/taxonkit

• ETE, version: 3.1.1
• BioPython, version: 1.73
• taxadb, version: 0.10.1
• TaxonKit, version: 0.5.0

Address of the bookmark: https://pypi.org/project/ete3/3.1.1/

Address of the bookmark: https://github.com/wtmatlock/flanker

Address of the bookmark: http://scikit-bio.org/