BOL: Related items

NRCO Vacancies For Junior Research Fellow – Pakyong, Sikkim

Thu, 28 May 2015 19:10:07 -0500

Junior Research Fellow
Pay Scale:Rs 25,000/-
Educational Requirements:MSc (with NET qualification) / M.Tech degree (with or without NET) with minimum 55% marks in Biotechnology/ Bioinformatics/ Molecular Biology or any other related field.
Other Qualification:Computer Skills (Linux, Perl, Java, MySQL) with experience in advanced molecular Biology techniques.
No of Post: 01
How To Apply: Walk-in-Interviews will be held at ICAR-National Research Centre for Orchids,Pakyong 737106, Sikkim for the post of 01 (One) Junior Research Fellow and 01 (One) Project Attendant under Project ‘DBT’s Twinning programme for the NE’ titled “Assessment of chemical and genetic divergence of some fragrant orchids of north-east India for sustainable improvement of community livelihood” as indicated below. The appointment will be on contractual basis and the incumbents shall not have any claim for regular appointment in ICAR.

Details will be available at: http://nrcorchids.nic.in/Employments/Vacancy%20-%20JRF.pdf

Human Complete Genome

Shruti Paniwala — Wed, 06 Jul 2022 06:42:55 -0500

Telomere-to-telomere consortium

We have sequenced the CHM13hTERT human cell line with a number of technologies. Human genomic DNA was extracted from the cultured cell line. As the DNA is native, modified bases will be preserved. The data includes 30x PacBio HiFi, 120x coverage of Oxford Nanopore, 70x PacBio CLR, 50x 10X Genomics, as well as BioNano DLS and Arima Genomics HiC. Most raw data is available from this site, with the exception of the PacBio data which was generated by the University of Washington/PacBio and is available from NCBI SRA.

A UCSC browser is available for v2.0 (as well as legacy v1.0 and v1.1 versions). An interactive dotplot visualization of all genomic repeats is also available from resgen.io. Known issues identified in the assembly are tracked at CHM13 issues.

MORE at https://github.com/marbl/CHM13

Address of the bookmark: https://www.science.org/doi/10.1126/science.abj6987

Nicolas Corradi Lab

Tue, 26 May 2015 16:19:02 -0500

The goal of our research is to better understand the biology of microbial organisms of significant ecological, veterinary and medical importance.
To achieve this goal, our team combines the power of next generation DNA sequencing and bioinformatics with molecular biology and experimental procedures.

Main research topics:
- Comparative and Population Genomics of Plant Symbionts
- Parasite Genome Evolution
- Experimental Evolution of Microbial Symbionts and Parasites
- Phylogenomics of Early Branching Fungi

More at http://corradilab.weebly.com/

Genome Context Viewer (GCV)

LEGE — Sun, 21 May 2023 19:33:43 -0500

The Genome Context Viewer (GCV) is a web-app that visualizes genomic context data provided by third party services. Specifically, it uses functional annotations as a unit of search and comparison. By adopting a common set of annotations, data-store operators can deploy federated instances of GCV, allowing users to compare genomes from different providers in a single interface.

Address of the bookmark: https://github.com/legumeinfo/gcv

Assistant Professor, Central University of Himachal Pradesh, India

Thu, 28 May 2015 19:22:49 -0500

Central University of Himachal Pradesh

PO Box: 21

DHARAMSHALA, DISTRICT KANGRA, HIMACHAL PRADESH – 176215

EMPLOYMENT NOTICE NO.: 02 / 2015

APPOINTMENT TO VARIOUS TEACHING, NON-TEACHING AND OTHER ACADEMIC STAFF POSITIONS

Applications in the prescribed form are invited from the eligible candidates for the following Teaching, Non-Teaching and other Academic Staff positions to be filled up on regular basis: Details of teaching positions:

15. School of Life Sciences

Computational Biology & Bioinformatics

1 (ST - 1) 2 (UR - 2)

Last Date of receipt of applications: 22ND JUNE, 2015

http://www.cuhimachal.ac.in/download/2015/may-2015/emp-notice-eng/1.%20Employment%20Notice%20No.%2002-2015%20dated%2019.05.2015_for%20Website.pdf

Entire Human Genome Sequencing !

LEGE — Tue, 02 Apr 2024 01:19:29 -0500

Cost-effective whole human genome sequencing has revolutionized the landscape of genetic research and personalized medicine by making comprehensive genetic analysis accessible to a wider population. Through advancements in sequencing technologies, such as next-generation sequencing (NGS), costs have significantly decreased, enabling researchers and healthcare providers to analyze an individual's complete genetic makeup with greater efficiency and affordability. This has profound implications for disease diagnosis, prognosis, and treatment, as it allows for the identification of genetic predispositions and the customization of healthcare interventions based on an individual's unique genetic profile. Moreover, as the cost continues to decline, the potential for population-scale genomic studies and large-scale screening programs becomes increasingly feasible, promising to further enhance our understanding of human genetics and improve healthcare outcomes on a global scale.

Here are few companies:

https://mynucleus.com/

https://myome.com/

https://nebula.org/whole-genome-sequencing-dna-test/

RECRUITMENT FOR 6 POSITIONS OF JRF (Junior Research Fellow)

Thu, 04 Jun 2015 15:22:54 -0500

Institute of Bioresources and Sustainable Development (IBSD), a National Institute of the Department of Biotechnology, Government of India invites applications for 6 positions of JRF for 2015. The main mandate of IBSD is Conservation and Sustainable Utilization of Bioresources for the Socio-economic Development of the North East Region of India, which is a genetic treasure trove of plants, animals and microbial resources. This region falls among the World’s top 10 Biodiversity Hotspots. The broad areas of research are in Plant Bioresources, Microbial Resources, Natural Product Chemistry, Animal Bioresources and Bioinformatics and Database Management.

Minimum qualifications: M.Sc. with minimum 55% for general and OBD Category (55% for SC/St/PH) in the above-mentioned subject areas (viz. Biotechnology, Life Sciences, Microbiology, Botany, Plant Sciences, Chemistry, Zoology, Animal Sciences, Fishery Sciences and any other relevant branches).

Preference will be given to those holding valid CSIR-UGC NET JRF. DBT-JRF, ICAR-JRF, ICMR-JRF and DST-INSPIRE Fellowship while NET/SLET/SET qualified and GATE qualified candidates (90 or above percentile) are also encouraged to apply. Reservations of seats: 15% for SC, 7.5% for ST, 27% for OBC (noncreamy layer) and 3% for Physically Handicapped as per statutory norms.

Selection Procedure: If the number of JRF and INSPIRE qualified candidates is more, selection will be based on interview of the JRF and INSPIRE qualified candidates only. The selected candidates may be registered for Ph.D. in any of the recognized Universities in India.

Application Procedure: Application should be sent in the prescribed application form (available on the IBSD website). The candidate should send the completed and signed form along with self attested copies of all supporting certificates and marksheets along with an application fee of Rs.300/- (For GEN/OBC/PH) & Rs.150/- for (SC/ST), for which a Demand Draft in favour of ‘Institute of Bioresources and Sustainable Development, payable at Imphal, Manipur, should be attached with the application form. Candidates are advised to provide their email ID and mobile number as they would be contacted electronically by the Institute. Duly filled applications (with ‘Application for IBSD PhD Programme’ super scribed on the envelope) should be sent to ‘The Director, Institute of Bioresources and Sustainable Development, Takyelpat, Imphal-795001, Manipur so as to reach on or before 6th of July, 2015. Applications send by email with scan copy of required enclosures will also be accepted and can be sent to director.ibsd@nic.in. However, in such instances, the application will be processed only after the receipt of the mailed hard copies.

Advertisement: http://ibsd.gov.in/jobs/phd_2015/IBSD_JRF_2015.pdf

Application Form : http://ibsd.gov.in/jobs/phd_2015/APPLICATION_FORM.pdf

Early Genome Screening: The New Health Horoscope!

LEGE — Thu, 02 Jan 2025 19:44:36 -0600

In an era where precision medicine is reshaping healthcare, genome screening is emerging as the modern equivalent of a health horoscope. It offers insights into our biological "stars," unraveling predispositions to various conditions and empowering individuals with knowledge to navigate their health journeys proactively. But how reliable is this "horoscope," and how does it impact our lives?

Understanding Genome Screening

Genome screening involves analyzing an individual's DNA to identify genetic variations that may influence health and disease susceptibility. This can range from simple single-gene tests to comprehensive whole-genome sequencing. By peering into our genetic blueprint, we can uncover risks for conditions like cancer, diabetes, cardiovascular diseases, and even rare genetic disorders.

The process is straightforward: a saliva or blood sample is collected, and advanced sequencing technologies decipher the genetic code. The results provide a personalized health map, guiding lifestyle modifications, preventive measures, or medical interventions.

A Shift from Reactive to Proactive Healthcare

Traditional healthcare often focuses on treating diseases after they manifest. Genome screening flips this model on its head, enabling a shift toward prevention and early intervention. For instance:

Cancer Risk Management: Individuals with BRCA1 or BRCA2 gene mutations can opt for enhanced screening programs or preventive surgeries to mitigate their risk of breast and ovarian cancers.
Cardiovascular Health: Genetic predispositions to conditions like familial hypercholesterolemia can prompt early cholesterol monitoring and lifestyle adjustments.
Rare Diseases: Identifying carriers of genetic disorders can aid in family planning and reduce the incidence of inherited conditions.

The Ethical and Practical Concerns

While genome screening offers incredible promise, it is not without challenges:

Accuracy and Interpretation: Genetic predisposition does not guarantee disease. Misinterpretation of results can lead to unnecessary anxiety or unwarranted medical interventions.
Privacy and Data Security: Genetic data is highly sensitive. Ensuring robust data protection measures is crucial to prevent misuse.
Accessibility and Equity: High costs and limited availability may restrict access to genome screening, exacerbating health disparities.

Balancing Science and Pseudoscience

The comparison of genome screening to horoscopes isn’t entirely unfounded. Both offer predictive insights, but the scientific foundation of genome screening distinguishes it from astrology. Unlike the alignment of celestial bodies, genetic predictions are based on rigorous data and evidence. However, the probabilistic nature of genetic predispositions underscores the importance of interpreting results in conjunction with clinical and lifestyle factors.

The Road Ahead

As genome screening becomes more affordable and integrated into routine healthcare, its potential to transform lives is immense. Policymakers, healthcare providers, and genetic counselors must collaborate to ensure ethical implementation, public awareness, and equitable access.

Imagine a future where your genetic "horoscope" is a trusted guide, not just a prediction. Early genome screening could help chart a healthier path for generations, making it a cornerstone of personalized medicine. After all, our genes might just hold the key to unlocking a future of better health and well-being.

Rosalind Problem Solution with Perl

Jit — Tue, 09 Jun 2015 23:35:18 -0500

Rosalind is a platform for learning bioinformatics and programming through problem solving. Take a tour to get the hang of how Rosalind works.

Bioinformatics Textbook Track

Find more about Rosalind puzzle at http://rosalind.info/problems/list-view/?location=bioinformatics-textbook-track

I will provide solution of all the Rosalind problem with Perl for community.

Check out the right sidebar for more links ...

High Density Sheep SNP Genotyping Chip released!!!

Rahul Agarwal — Tue, 03 Sep 2013 13:58:04 -0500

If you are working on Sheep genomics then there is a good news for you. FarmIQ in conjunction with Illumina and the International Sheep Genomics Consortium (ISGC) are today announcing completion of the “Ovine Infinium® HD SNP BeadChip”, a high definition SNP chip for ship genome. The OvineSNP50 BeadChip features over 54,241 evenly spaced probes that target SNPs, offering more than sufficient SNP density for genome-wide association studies and other applications such as genome-wide selection, determination of genetic merit, identification of quantitative trait loci, and comparative genetic studies.

The BeadChip was developed in collaboration with leading ovine researchers from AgResearch, Baylor UCSC, CSIRO, and the USDA as part of the International Sheep Genomics Consortium. It features over 54,241 evenly spaced probes that target single nucleotide polymorphisms (SNPs). More than 18,000 of these markers were discovered through sequencing reduced representation libraries with the Illumina Genome Analyzer IIx. A set of 600 SNPs were identified by BAC end sequencing and validated with Illumina GoldenGate Genotyping Assays over 403 animals from 23 breeds. The remaining SNPs were derived from the draft ovine genome.